Cyclodextrins: Efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems

International Journal of Pharmaceutics

Volumn 422, Issue 1-2, 2012, Pages 349-355

  Stojanov, Mladen ^a   Nielsen, Hanne Mørck ^b   Larsen, Kim L ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Bromhexine; Cellular viability; Complex formation; Cyclodextrin; DLS; ITC; Solubility; Stoichiometry; Structure

Indexed keywords

ALPHA CYCLODEXTRIN; BETA CYCLODEXTRIN SULFOBUTYL ETHER; BROMHEXINE; GAMMA CYCLODEXTRIN;

AQUEOUS SOLUTION; ARTICLE; BIOCOMPATIBILITY; CALORIMETRY; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STRUCTURE; EXCIPIENT COMPATIBILITY; PRIORITY JOURNAL; SIGNAL NOISE RATIO; SOLUBILIZATION;

ALPHA-CYCLODEXTRINS; ANIMALS; BETA-CYCLODEXTRINS; BIOCOMPATIBLE MATERIALS; BROMHEXINE; CALORIMETRY; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; EXCIPIENTS; EXPECTORANTS; GAMMA-CYCLODEXTRINS; HELA CELLS; HEMOLYSIS; HORSES; HUMANS; PARTICLE SIZE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 84655169992     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.10.023     Document Type: Article

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