Clinical reagents of GM-CSF and IFN-α induce the generation of functional chronic myeloid leukemia dendritic cells in vitro

Cytotechnology

Volumn 64, Issue 1, 2012, Pages 75-81

  Weng, Kaizhi ^a   Xie, Xiaobao ^b   Qiu, Guoqiang ^b   Gu, Weiying ^b  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

Chronic myeloid leukemia; Clinical reagents; Dendritic cells

Indexed keywords

ALPHA INTERFERON; B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 4;

ARTICLE; CELL FUNCTION; CELL STRUCTURE; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL FEATURE; CONCENTRATION RESPONSE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPHENOTYPING; IN VITRO STUDY; PROTEIN INDUCTION; UPREGULATION;

EID: 84655167126     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-011-9393-2     Document Type: Article

References (19)

1. J Banchereau AK Palucka 2005 Dendritic cells as therapeutic vaccines against cancer Nat Rev Immunol 5 296 306 10.1038/nri1592 1:CAS:528: DC%2BD2MXivVaku7c%3D (Pubitemid 40516155)
2. F Belardelli M Ferrantini 2002 Cytokines as a link between innate and adaptive antitumor immunity Trends Immunol 23 201 208 10.1016/S1471-4906(02) 02195-6 1:CAS:528:DC%2BD38XitlGhs7k%3D (Pubitemid 34260936)
3. F Belardelli M Ferrantini E Proietti JM Kirkwood 2002 Interferon-alpha in tumor immunity and immunotherapy Cytokine Growth Factor Rev 13 119 134 10.1016/S1359-6101(01)00022-3 1:CAS:528:DC%2BD38XitFWhsrk%3D (Pubitemid 34229387)
4. C Carbonneil H Saidi V Donkova-Petrini L Weiss 2004 Dendritic cells generated in the presence of interferon-alpha stimulate allogeneic CD4 + T-cell proliferation: modulation by autocrine IL-10, enhanced T-cell apoptosis and T regulatory type 1 cells Int Immunol 16 1037 1052 10.1093/intimm/dxh106 1:CAS:528:DC%2BD2cXltVWntb4%3D (Pubitemid 38960882)
5. J Cortes H Kantarjian S O'Brien R Kurzroch M Keating M Talpaz 1998 GM-CSF can improve the cytogenetic response obtained with interferon-alpha therapy in patients with chronic myelogenous leukemia Leukemia 12 860 864 10.1038/sj.leu.2401033 1:CAS:528:DyaK1cXkt1Kiurs%3D (Pubitemid 28287206)
6. M Dauer B Obermaier J Herten C Haerle K Pohl S Rothenfusser M Schnurr S Endres A Eigler 2003 Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors J Immunol 170 4069 4076 1:CAS:528:DC%2BD3sXisleku70%3D (Pubitemid 36428169)
7. M Dauer K Schad J Junkmann C Bauer J Herten R Kiefl M Schnurr S Endres A Eigler 2006 IFN-alpha promotes definitive maturation of dendritic cells generated by short-term culture of monocytes with GM-CSF and IL-4 J Leukoc Biol 80 278 286 10.1189/jlb.1005592 1:CAS:528:DC%2BD28Xot1OnsLs%3D (Pubitemid 44835501)
8. L Gabriele P Borghi C Rozera P Sestili M Andreotti A Guarini E Montefusco R Foà F Belardelli 2004 IFN-alpha promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment Blood 103 980 987 10.1182/blood-2003-03-0981 1:CAS:528:DC%2BD2cXhtVaksrg%3D (Pubitemid 38129560)
9. D Gabrilovich 2004 Mechanisms and functional significance of tumour-induced dendritic-cell defects Nat Rev Immunol 4 941 952 10.1038/nri1498 1:CAS:528:DC%2BD2cXhtVarsb7P (Pubitemid 39620069)
10. SM Kiertscher MD Roth 1996 Human CD14 + leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4 J Leukoc Biol 59 208 218 1:CAS:528:DyaK28XhtlKgu70%3D (Pubitemid 26097650)
11. M Korthals N Safaian R Kronenwett D Maihöfer M Schott C Papewalis E Diaz Blanco M Winter A Czibere R Haas G Kobbe R Fenk 2007 Monocyte derived dendritic cells generated by IFN-alpha acquire mature dendritic and natural killer cell properties as shown by gene expression analysis J Transl Med 5 46 10.1186/1479-5876-5-46 (Pubitemid 350066534)
12. C Lapenta SM Santini M Spada S Donati F Urbani D Accapezzato D Franceschini M Andreotti V Barnaba F Belardelli 2006 IFN-alpha-conditioned dendritic cells are highly efficient in inducing cross-priming CD8(+) T cells against exogenous viral antigens Eur J Immunol 36 2046 2060 10.1002/eji. 200535579 1:CAS:528:DC%2BD28XovFGgtbo%3D (Pubitemid 44251751)
13. A Le Bon G Schiavoni G D'Agostino I Gresser F Belardelli DF Tough 2001 Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo Immunity 14 461 470 10.1016/S1074-7613(01)00126-1 1:CAS:528:DC%2BD3MXjsVent74%3D (Pubitemid 32441598)
14. SH Lim S Coleman R Bailey-Wood 1998 In vitro cytokine-primed leukaemia cells induce in vivo T cell responsiveness in chronic myeloid leukaemia Bone Marrow Transplant 22 1185 1190 10.1038/sj.bmt.1701511 1:STN:280: DyaK1M7htVSisQ%3D%3D (Pubitemid 29021128)
15. M Mohty D Jarrossay M Lafage-Pochitaloff C Zandotti F Brière XN de Lamballeri D Isnardon D Sainty D Olive B Gaugler 2001 Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment Blood 98 3750 3756 10.1182/blood.V98.13.3750 1:CAS:528:DC%2BD3MXptFOjtLg%3D
16. ES Trombetta I Mellman 2005 Cell biology of antigen processing in vitro and in vivo Annu Rev Immunol 23 975 1028 10.1146/annurev.immunol.22.012703. 104538 1:CAS:528:DC%2BD2MXktFOisr4%3D (Pubitemid 40563191)
17. C Wang HM Al-Omar L Radvanyi A Banerjee D Bouman J Squire HA Messner 1999 Clonal heterogeneity of dendritic cells derived from patients with chronic myeloid leukemia and enhancement of their T-cells stimulatory activity by IFN-alpha Exp Hematol 27 1176 1184 10.1016/S0301-472X(99)00055-7 1:CAS:528:DyaK1MXktlSgsbk%3D (Pubitemid 29284325)
18. TL Whiteside C Odoux 2004 Dendritic cell biology and cancer therapy Cancer Immunol Immunother 53 240 248 10.1007/s00262-003-0468-6 (Pubitemid 38328047)
19. CY Wu LS Zhang YF Zhang Y Chai LC Yi FX Song 2005 In vitro inducing differentiation of bone marrow mononuclear cells of chronic myeloid leukemia Ai Zheng 24 425 431 1:CAS:528:DC%2BD28Xit1Wgsrg%3D