Sustained response following sorafenib therapy in an older adult patient with advanced renal cancer on hemodialysis: A case report

Medical Oncology

Volumn 28, Issue 4, 2011, Pages 1384-1388

  Castagneto, B ^a   Stevani, I ^a   Giorcelli, L ^a   Montefiore, F ^a   Bigatti, G L ^a   Pisacco, P ^a   Cosimi, M F ^a  

^a San Giacomo Hospital Novi Ligure   (Italy)

Author keywords

Hemodialysis; Kidney cancer; Older; Sorafenib; Targeted therapy

Indexed keywords

IBANDRONIC ACID; SORAFENIB;

AGED; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DRUG DOSE REDUCTION; FOLLOW UP; HAND FOOT SYNDROME; HEMODIALYSIS; HUMAN; IRRADIATION; KIDNEY CANCER; LUNG METASTASIS; MALE; PRIORITY JOURNAL; TREATMENT RESPONSE;

AGED; ANTINEOPLASTIC AGENTS; BENZENESULFONATES; CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; MALE; NEOPLASM METASTASIS; PYRIDINES; RENAL DIALYSIS;

EID: 84655165066     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9595-z     Document Type: Article

References (12)

1. LJ Costa HA Drabkin 2007 Renal cell carcinoma: new developments in molecular biology and potential for targeted therapies Oncologist 12 1404 1415
2. RJ Motzer NH Bander DM Nanus 1996 Renal-cell carcinoma N Engl J Med 335 865 875
3. SM Wihelm 2004 BAY 43-9006 exhibits broad spectrum oral antitumour activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumour progression and angiogenesis Cancer Res 64 7099 7109
4. MM Oken 1982 Toxicity and response criteria of the Eastern Cooperative Oncology Group Am J Clin Oncol 5 649 655
5. B Escudier 2007 Sorafenib in advanced clear-cell renal-cell carcinoma N Engl Med 356 125 134
6. RJ Motzer 2007 Sunitinib versus interferon alfa in metastatic renal cell carcinoma N Engl Med 356 115 124
7. C Lathia 2006 Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics Cancer Chemother Pharmacol 57 685 692
8. AA Miller 2009 Phase I and Pharmacokinetic Study of Sorafenib in patients with Hepatic or Renal Dysfunction: CALGB 60301 J Clin Oncol 27 1800 1805
9. G Papi 2007 Metastases to the thyroid gland: prevalence, clinicopathological aspects and prognosis: a 10 year experience Clin Endocrinol (Oxf) 66 565 571
10. N Wada 2005 Solitary metachronous metastasis to the thyroid from renal clear cell carcinoma 19 years after nephrectomy: report of a case Surg Today 35 483 487
11. RA Hilger 2009 Pharmacokinetics in patients with renal impairment undergoing hemodialysis Int J Clin Pharmacol Ther 47 61 64
12. R Bernabei V Venturiero P Tarsitani G Gambassi 2000 The comprehensive geriatric assessment: when, where, how Crit Rev Oncol Hematol 33 45 56