-
1
-
-
0036983115
-
The Ras-Raf-MEK-ERK pathway in the treatment of cancer
-
Hilger RA, Scheulen ME, Strumberg D. The Ras-Raf-MEK-ERK pathway in the treatment of cancer. Onkologie. 2002; 25: 511-518.
-
(2002)
Onkologie
, vol.25
, pp. 511-518
-
-
Hilger, R.A.1
Scheulen, M.E.2
Strumberg, D.3
-
2
-
-
1342271451
-
ERK1/2 phosphorylation: A biomarker analysis within a phase I study with the new Raf kinase inhibitor BAY43-9006
-
Hilger RA, Kredtke S, Hedley D, Moeller JG, Bauer RJ, Stellberg W, Seeber S, Scheulen ME, Strumberg D. ERK1/2 phosphorylation: a biomarker analysis within a phase I study with the new Raf kinase inhibitor BAY43-9006. Int J Clin Pharmacol Ther. 2002; 40: 567-568.
-
(2002)
Int J Clin Pharmacol Ther
, vol.40
, pp. 567-568
-
-
Hilger, R.A.1
Kredtke, S.2
Hedley, D.3
Moeller, J.G.4
Bauer, R.J.5
Stellberg, W.6
Seeber, S.7
Scheulen, M.E.8
Strumberg, D.9
-
3
-
-
1542437244
-
Circadian rhythm in the regulation of the MAP kinase pathway - pitfall in the determination of surrogate parameters?
-
Hilger RA, Díaz-Carballo D, Bauer S, Kredtke S, Scheulen ME, Seeber S, Strumberg D. Circadian rhythm in the regulation of the MAP kinase pathway - pitfall in the determination of surrogate parameters? Int J Clin Pharmacol Ther. 2003; 41: 614-615.
-
(2003)
Int J Clin Pharmacol Ther
, vol.41
, pp. 614-615
-
-
Hilger, R.A.1
Díaz-Carballo, D.2
Bauer, S.3
Kredtke, S.4
Scheulen, M.E.5
Seeber, S.6
Strumberg, D.7
-
4
-
-
16644389620
-
Correlation of ERK-phosphorylation and toxicities in patients treated with the Raf kinase inhibitor BAY 43-9006
-
Hilger RA, Kredtke S, Scheulen ME, Seeber S, Strumberg D. Correlation of ERK-phosphorylation and toxicities in patients treated with the Raf kinase inhibitor BAY 43-9006. Int J Clin Pharmacol Ther. 2004; 42: 648-649.
-
(2004)
Int J Clin Pharmacol Ther
, vol.42
, pp. 648-649
-
-
Hilger, R.A.1
Kredtke, S.2
Scheulen, M.E.3
Seeber, S.4
Strumberg, D.5
-
5
-
-
32944478104
-
Results of a phase I trial of sorafenib (BAY 43-9006) in combination with oxaliplatin in patients with refractory solid tumors, including colorectal cancer
-
Kupsch P, Henning BF, Passarge K, Richly H, Wiesemann K, Hilger RA, Scheulen ME, Christensen O, Brendel E, Schwartz B, Hofstra E, Voigtmann R, Seeber S, Strumberg D. Results of a phase I trial of sorafenib (BAY 43-9006) in combination with oxaliplatin in patients with refractory solid tumors, including colorectal cancer. Clin Colorectal Cancer. 2005; 5: 188-196.
-
(2005)
Clin Colorectal Cancer
, vol.5
, pp. 188-196
-
-
Kupsch, P.1
Henning, B.F.2
Passarge, K.3
Richly, H.4
Wiesemann, K.5
Hilger, R.A.6
Scheulen, M.E.7
Christensen, O.8
Brendel, E.9
Schwartz, B.10
Hofstra, E.11
Voigtmann, R.12
Seeber, S.13
Strumberg, D.14
-
6
-
-
33645648696
-
Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics
-
Lathia C, Lettieri J, Cihon F, Gallentine M, Radtke M, Sundaresan P. Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics. Cancer Chemother Pharmacol. 2006; 57: 685-692.
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 685-692
-
-
Lathia, C.1
Lettieri, J.2
Cihon, F.3
Gallentine, M.4
Radtke, M.5
Sundaresan, P.6
-
7
-
-
1542542000
-
-
Mross K, Steinbild S, Baas F, Reil M, Buss P, Mersmann S, Voliotis D, Schwartz B, Brendel E. Drug-drug interaction pharmacokinetic study with the Raf kinase inhibitor (RKI) BAY43-9006 administered in combination with irinotecan (CPT-11) in patients with solid tumors. Int J Clin Pharmacol Ther. 2003; 41: 618-619.
-
Mross K, Steinbild S, Baas F, Reil M, Buss P, Mersmann S, Voliotis D, Schwartz B, Brendel E. Drug-drug interaction pharmacokinetic study with the Raf kinase inhibitor (RKI) BAY43-9006 administered in combination with irinotecan (CPT-11) in patients with solid tumors. Int J Clin Pharmacol Ther. 2003; 41: 618-619.
-
-
-
-
8
-
-
33746556990
-
Syntheses of [2H3,15N], [14C]NexavarTM and its labelled metabolites
-
Pleiss U, Gerisch M, Seidel D. Syntheses of [2H3,15N], [14C]NexavarTM and its labelled metabolites. J Label Comp Radiopharm. 2006; 49: 603-613.
-
(2006)
J Label Comp Radiopharm
, vol.49
, pp. 603-613
-
-
Pleiss, U.1
Gerisch, M.2
Seidel, D.3
-
9
-
-
33646204716
-
Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors
-
Richly H, Henning BF, Kupsch P, Passarge K, Grubert M, Hilger RA, Christensen O, Brendel E, Schwartz B, Ludwig M, Flashar C, Voigtmann R, Scheulen ME, Seeber S, Strumberg D. Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors. Ann Oncol. 2006; 17: 866-873.
-
(2006)
Ann Oncol
, vol.17
, pp. 866-873
-
-
Richly, H.1
Henning, B.F.2
Kupsch, P.3
Passarge, K.4
Grubert, M.5
Hilger, R.A.6
Christensen, O.7
Brendel, E.8
Schwartz, B.9
Ludwig, M.10
Flashar, C.11
Voigtmann, R.12
Scheulen, M.E.13
Seeber, S.14
Strumberg, D.15
-
10
-
-
20044382799
-
Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
Strumberg D, Richly H, Hilger RA, Schleucher N, Korfee S, Tewes M, Faghih M, Brendel E, Voliotis D, Haase CG, Schwartz B, Awada A, Voigtmann R, Scheulen ME, Seeber S. Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol. 2005; 23: 965-972.
-
(2005)
J Clin Oncol
, vol.23
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
Schleucher, N.4
Korfee, S.5
Tewes, M.6
Faghih, M.7
Brendel, E.8
Voliotis, D.9
Haase, C.G.10
Schwartz, B.11
Awada, A.12
Voigtmann, R.13
Scheulen, M.E.14
Seeber, S.15
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