Hippocampus/amygdala alterations, loss of heparan sulfates, fractones and ventricle wall reduction in adult BTBR T+ tf/J mice, animal model for autism

Neuroscience Letters

Volumn 506, Issue 2, 2012, Pages 208-213

  Mercier, Frederic ^a   Kwon, Youngsu Cho ^a   Douet, Vanessa ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

Amygdala; Autism; Choroid plexus; Heparan sulfate proteoglycans; Hippocampus; Meninges

Indexed keywords

LAMININ; PROTEOHEPARAN SULFATE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN; BRAIN VENTRICLE; CELL NUCLEUS; CHOROID PLEXUS; DENTATE GYRUS; FEMALE; HIPPOCAMPUS; HISTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; MALE; MENINX; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMYGDALA; ANIMALS; AUTISTIC DISORDER; CEREBRAL VENTRICLES; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HEPARITIN SULFATE; HIPPOCAMPUS; MALE; MICE; MICE, NEUROLOGIC MUTANTS;

EID: 84655164274     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.11.007     Document Type: Article

References (28)

1. Ashwell K.W., White P.M., Marotte L. Ontogeny of the projection tracts and commissural fibres in the forebrain of the tammar wallaby (Macropus Eugenii): timing in comparison with other mammals. Brain Behav. Evol. 1996, 47:8-22.
2. Aviezer D., Hecht D., Safran M., Elsinger M., David G., Yayon A. Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis and angiogenesis. Cell 1994, 79:1005-1013.
3. Bachevalier J. Medial temporal lobe structures and autism: a review of clinical and experimental findings. Neuropsychologia 1994, 32:627-648.
4. Barnea-Goraly N., Kwon H., Menon V., Eliez S., Lotspeich L., Reiss A.L. White mater structures in autism: preliminary evidence from diffusion tensor imaging. Biol. Psychiatry 2004, 55:323-326.
5. Baron-Cohen S., Ring H.A., Bullmore E.T., Wheelwright S., Ashwin C., Williams S.C.R. The amygdala theory of autism. Neurosci. Biobehav. Rev. 2000, 24:355-364.
6. Brickman Y.G., Ford M.D., Small D.H., Bartlett P.F., Nurcombe V. Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cells. J. Biol. Chem. 1995, 270:24941-24948.
7. Courchesne E., Pierce K. Brain development in autism: early overgrowth followed by premature arrest of growth. Ment. Retard. Dev. Disabil. Res. Rev. 2004, 10:106-111.
8. David G., Mei Bai X., Van Der Schueren B., Cassiman J.J., Van Den Berghe H. Developmental changes in heparan sulfate expression: in situ detection with mAbs. J. Cell Biol. 1992, 119:961-975.
9. Finley B.L., Darlington R.B. Linked regularities in the development and evolution of mammalian brains. Science 1995, 268:1578-1584.
10. Howard M.A., Cowell P.E., Boucher J., Broks P., Mayes A., Farrant A., Roberts N. Convergent neuroanatomical and behavioural evidence of an amygdala hypothesis of autism. Neuroreport 2000, 11:2931-2935.
11. Kaufmann M.H. The Atlas of Mouse Development 2005, Elsevier, Acad. Press, Amsterdam, p. 525.
12. Kerever A., Schnack J., Vellinga D., Ichikawa N., Moon C., Arikawa-Hirasawa E., Efird J.T., Mercier F. Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor FGF-2 from the extracellular milieu. Stem Cells 2007, 25:2146-2157.
13. McFarlane H.G., Kusek G.K., Yang M., Phoenix J.L., Bolivar V.J., Crawley J.N. Autism-like behavioral phenotypes in BTBR T+ tf/J mice. Genes Brain Behav. 2008, 7:152-163.
14. Mercier F., Cho Kwon Y.Y., Kodama Rich R. Meningeal/vascular alterations and loss of extracellular matrix in the neurogenic zone of the adult brain BTBR T+ tf/J mice, animal model for autism. Neurosci. Lett. 2011, 498:173-178.
15. Mercier F., Hatton G.I. Immunocytochemical basis for a meningeo-glial network. J. Comp. Neurol. 2000, 420:445-465.
16. Mercier F., Kitasako J.T., Hatton G.I. Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast/macrophage network. J. Comp. Neurol. 2002, 451:170-188.
17. Mercier F., Kitasako J.T., Hatton G.I. Fractones and other basal laminae in the hypothalamus. J. Comp. Neurol. 2003, 455:324-340.
18. Mercier F., Shnack J., Saint Georges Chaumet M. Fractones: home and conductors of the neural stem cell niche. Neurogenesis in the Adult Brain 2011, Springer Verlag Pub., (Chapt. 4). A. Alvarez-Buylla, J.M. Parent, K. Sawamoto, T. Seki (Eds.).
19. Moy S.S., Nadler J.J., Young N.B., Perez A., Holloway L.P., Barbaro R.P., Barbaro J.R., Wilson L.M., Threadgill D.W., Lauder J.M., Magnuson T.R., Crawley J.N. Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav. Brain Res. 2007, 176:4-20.
20. Pardo C.A., Eberhart C.G. The neurobiology of autism. Brain Pathol. 2007, 17:24-30.
21. Roberts R., Ghallager J., Spooncer E., Allen T.D., Bloomfield F., Dexter T.M. Heparan-sulfate bound growth factors: a mechanism for stromal cell mediated hematopoesis. Nature 1988, 332:376-378.
22. Schumann C.M., Hamstra J., Goodlin-Jones B.L., Lotspeich L.J., Kwon H., Buonocore M.H., Lammers C.R., Reiss A.L., Amaral D.G. The amygdala is enlarged in children but not adolescents with autism: the hippocampus is enlarged in all ages. J. Neurosci. 2004, 24:6392-6401.
23. Siegenthaler J.A., Asthique A.M., Zarbalis K., Patterson K.P., Hecht J.H., Kane M.A., Folias A.M., Choe Y., May S.R., Kume T., Napoli J.L., Peterson A.S., Pleasure S.J. Retinoic acid from the meninges regulates cortical neuron generation. Cell 2009, 139:597-609.
24. Sievers J., Pehlemann J., Berry M. Influences of meningeal cells on brain development. Findings and hypothesis. Naturwissenshaften 1986, 73:188-194.
25. Stephenson D.T., O'Neill S.M., Narayan S., Tiwari A., Arnold E., Samaroo H.D., Du F., Ring H., Campbell B., Pletcher M., Vaidya V.A., Morton D. Histopathological characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis. Mol. Autism 2011, 2:7.
26. Sturrock R.R. A morphological study of the development of the mouse choroid plexus. J. Anat. 1979, 129:777-793.
27. Wahlsten D. Growth of the mouse corpus callosum. Dev. Brain Res. 1984, 5:59-67.
28. Wahlsten D., Metten P., Crabbe J.C. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res. 2003, 971:47-54.