Novel immunomodulators based on an oxazolin-2-one-4-carboxamide scaffold

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 553-557

  He, Xinhua ^a   Wang, Lili ^a   Zheng, Zhibing ^a   Xiao, Junhai ^a   Zhong, Wu ^a   Li, Song ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Immunosuppressive agent; Oxazolidin 2 one 4 carboxylic amide; S1P 1 receptor

Indexed keywords

FINGOLIMOD; IMMUNOSUPPRESSIVE AGENT; MOLECULAR SCAFFOLD; OXAZOLIN 2 ONE 4 CARBOXAMIDE; OXAZOLINE DERIVATIVE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IMMUNOMODULATION; IN VITRO STUDY; MOLECULAR MODEL; NONHUMAN;

AMIDES; AMINO ACIDS; BENZAMIDES; CATALYTIC DOMAIN; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HUMANS; HYDROGEN BONDING; IMMUNOLOGIC FACTORS; IMMUNOSUPPRESSIVE AGENTS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OXAZOLONE; PROPYLENE GLYCOLS; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE;

EID: 84655161360     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.10.088     Document Type: Article

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