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Volumn 18, Issue 1, 2012, Pages 76-79

Enantioselective one-pot synthesis of α-amino esters by a phosphine-catalyzed [3+2]-cycloaddition reaction

Author keywords

amino esters; asymmetric synthesis; cycloaddition; organocatalysis; phosphines

Indexed keywords

ALLENES; AMINO ESTERS; ASYMMETRIC SYNTHESIS; AZLACTONES; CYCLOADDITION REACTION; ENANTIOSELECTIVE; HIGH ENANTIOSELECTIVITY; KETOESTER; ONE POT; ONE-POT SYNTHESIS; ORGANOCATALYSIS; PHOSPHINES; REGIOISOMERS; RING OPENING;

EID: 84555196459     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201103502     Document Type: Article
Times cited : (69)

References (53)
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    • For recent reviews, see
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    • For a review on azlactones in organocatalysis, see
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    • A.-N. R. Alba, R. Rios, Chem. Asian J. 2011, 6, 720. For an example of olefinic azlactones in organocatalysis, see
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    • Alba, A.-N.R.1    Rios, R.2
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    • During the work on this project, a racemic version of this transformation, including one enantioselective example, albeit with a low enantiomeric excess, was published:, Y.-Q. Zou, C. Li, J. Rong, H. Yan, J.-R. Chen, W.-J. Xiao, Synlett 2011, 1000.
    • (2011) Synlett , pp. 1000
    • Zou, Y.-Q.1    Li, C.2    Rong, J.3    Yan, H.4    Chen, J.-R.5    Xiao, W.-J.6
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    • For transformations on similar systems, see
    • For transformations on similar systems, see
  • 44
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    • The identity of the minor isomer was determined by NMR studies (see the Supporting Information)
    • The identity of the minor isomer was determined by NMR studies (see the Supporting Information).
  • 48
    • 38349137146 scopus 로고    scopus 로고
    • Kα radiation it is possible to determine the absolute configuration of the molecule in the crystal structure: The Flack parameter is 0.04(30) and the Hooft y parameter (, W. W. R. Hooft, L. H. Straver, A. L. Spek, J. Appl. Crystallogr. 2008, 41, 96-103) is 0.06(12), while the probability for the correct determination of the absolute configuration (P2) is 1.0. Ortep-3 wsa use for the X-ray plot
    • (2008) J. Appl. Crystallogr. , vol.41 , pp. 96-103
    • Hooft, W.W.R.1    Straver, L.H.2    Spek, A.L.3
  • 49
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    • L. J. Farrugia, J. Appl. Crystallogr. 1997, 30, 565. CDC-845884 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via.
    • (1997) J. Appl. Crystallogr. , vol.30 , pp. 565
    • Farrugia, L.J.1
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    • For related oxidations, see
    • For related oxidations, see


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.