Simulation of survivorship bias in observational studies on plasma to red blood cell ratios in massive transfusion for trauma

British Journal of Surgery

Volumn 99, Issue SUPPL. 1, 2012, Pages 132-139

  Ho, A M H ^a   Dion, P W ^e   Yeung, J H H ^a   Joynt, G M ^a   Lee, A ^a   Ng, C S H ^b   Chang, A ^b   So, F L ^c   Cheung, C W ^d  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b QUEEN ELIZABETH HOSPITAL   (Hong Kong)

^c TUEN MUN HOSPITAL   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e St Catharines General Site   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BLEEDING; BLOOD TRANSFUSION; EPIDEMIOLOGY; ERYTHROCYTE TRANSFUSION; FEMALE; HONG KONG; HUMAN; INJURY; MALE; MIDDLE AGED; MORTALITY; PLASMA; PROGNOSIS;

ADULT; BLOOD TRANSFUSION; EPIDEMIOLOGIC METHODS; ERYTHROCYTE TRANSFUSION; FEMALE; HEMORRHAGE; HONG KONG; HUMANS; MALE; MIDDLE AGED; PLASMA; PROGNOSIS; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 84555195375     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.7732     Document Type: Article

References (33)

1. Thorsen K, Ringdal KG, Strand K, Søreide E, Hagemo J, Søreide K,. Clinical and cellular effects of hypothermia, acidosis and coagulopathy in major injury. Br J Surg 2011; 98: 894-907.
2. Callum JL, Nascimento B, Tien H, Rizoli S,. Editorial: 'Formula-driven' versus 'lab-driven' massive transfusion protocols: at a state of clinical equipoise. Transfus Med Rev 2009; 23: 247-254.
3. Ho AMH, Dion PW, Yeung JHH, Ng CSH, Karmakar MK, Critchley LA, et al., Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common sense and sensibility. Resuscitation 2010; 81: 1079-1081.
4. American College of Surgeons. Advanced Trauma Life Support Program for Doctors (8th edn). American College of Surgeons: Chicago, 2008.
5. Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, et al., Management of bleeding following major trauma: an updated European guideline. Crit Care 2010; 14: R52.
6. American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology 2006; 105: 198-208.
7. Gaarder C, Naess PA, Christensen EF, Hakala P, Handolin L, Heier HE, et al., Scandinavian guidelines-'The massively bleeding patient'. Scand J Surg 2008; 97: 15-36. (Pubitemid 351449961)
8. Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, et al.,; Inflammation the Host Response to Injury Investigators. An FFP: PRBC transfusion ratio > / = 1: 1·5 is associated with a lower risk of mortality after massive transfusion. J Trauma 2008; 65: 986-993.
9. Holcomb JB, Wade CE, Michalek JE, Chisholm GB, Zarzabal LA, Schreiber MA, et al., Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg 2008; 248: 447-458.
10. Mitra B, Moria A, Cameron PA, Fitzgerald M, Paul E, Street A,. Fresh frozen plasma (FFP) use during massive blood transfusion in trauma resuscitation. Injury 2010; 41: 35-39.
11. Borgman MA, Spinella PC, Holcomb JB, Blackbourne LH, Wade CE, Lefering R, et al., The effect of FFP: RBC ratio on morbidity and mortality in trauma patients based on transfusion prediction score. Vox Sang 2011; 101: 44-54.
12. Kashuk JL, Moore EE, Johnson JL, Haenel J, Wilson M, Moore JB, et al., Postinjury life threatening coagulopathy: is 1: 1 fresh frozen plasma: packed red blood cells the answer? J Trauma 2008; 65: 261-270.
13. Teixeira PG, Inaba K, Shulman I, Salim A, Demetriades D, Brown C, et al., Impact of plasma transfusion in massively transfused trauma patients. J Trauma 2009; 66: 693-697.
14. Munro AR, Ferguson C,. Towards evidence based emergency medicine: best BETS from the Manchester Royal Infirmary. BET 1: blood component therapy in trauma patients requiring massive transfusion. Emerg Med J 2010; 27: 53-55.
15. Snyder CW, Weinberg JA, McGwin G Jr, Melton SM, George RL, Reiff DA, et al., The relationship of blood product ratio to mortality: survival benefit or survival bias? J Trauma 2009; 66: 358-362.
16. Sonnenberg FA, Beck JR,. Markov models in medical decision making: a practical guide. Med Decis Making 1993; 13: 322-338. (Pubitemid 24013155)
17. Riskin DJ, Tsai TC, Riskin L, Hernandiz-Boussard T, Purtill M, Maggio PM, et al., Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction. J Am Coll Surg 2009; 209: 198-205.
18. Fuller G, Bouamra O, Woodford M, Jenks T, Stanworth S, Allard S, et al., Recent massive blood transfusion practice in England and Wales: view from a trauma registry. Emerg Med J 2011; [Epub ahead of print].
19. Hoyt DB, Dutton RP, Hauser CJ, Hess JR, Holcomb JB, et al., Management of coagulopathy in the patients with multiple injuries: results from an international survey of clinical practice. J Trauma 2008; 65: 755-764.
20. Maegele M, Lefering R, Paffrath T, Tjardes T, Simanski C, Bouillon B, et al., Red-blood-cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiple injury: a retrospective analysis from the Trauma Registry of the Deutsche Gesellschaft für Unfallchirurgie. Vox Sang 2008; 952: 112-119. (Pubitemid 351951900)
21. Gonzalez EA, Moore FA, Holcomb JB, Miller CC, Kozar RA, Todd SR, et al., Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma 2007; 62: 112-119. (Pubitemid 46102840)
22. Duchesne JC, Hunt JP, Wahl G, Marr AB, Wang Y-Z, Weintraub SE, et al., Review of current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years? J Trauma 2008; 65: 272-276.
23. Stansbury LG, Dutton DP, Stein DM, Bochicchio GV, Scalea TM, Hess JR,. Controversy in trauma resuscitation: do ratios of plasma to red cells matter. Transfus Med Rev 2009; 23: 255-265.
24. Scalea TM, Bochiocchio KM, Lumpkins K, Hess JR, Dutton R, Pyle A, et al., Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients. Ann Surg 2008; 248: 578-584.
25. Cotton BA, Au BK, Nunez TC, Gunter OL, Robertson AM, Young PP,. Damage control hematology: the impact of a trauma exsanguination protocol on survival and blood product utilization. J Trauma 2008; 64: 1177-1182. (Pubitemid 351671208)
26. Zaydfudim V, Dutton WD, Feurer ID, Au BK, Pinson CW, Cotton BA,. Exsanguination protocol improves survival after major hepatic trauma. Injury 2010; 41: 30-34.
27. Duchesne JC, Barbeau JM, Islam TM, Wahl G, Greiffenstein P, McSwain NE Jr,. Damage control resuscitation: from emergency department to the operating room. Am Surg 2011; 77: 201-206.
28. Gunter OL Jr, Au BK, Isbell JM, Mowery NT, Young PP, Cotton BA,. Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival. J Trauma 2008; 65: 527-534.
29. Dente CJ, Shaz BH, Nicholas JM, Harris RS, Wyrzykowski AD, Patel S, et al., Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian level I trauma center. J Trauma 2009; 66: 1616-1624.
30. Suissa S,. Immortal time bias in pharmaco-epidemiology. Am J Epidemiol 2008; 167: 492-499.
31. Lévesque LE, Hanley JA, Kezouh A, Suissa S,. Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ 2010; 340: 907-911.
32. Rainer TH, Ho AMH, Yeung JHH, Cheung NK, Wong RS, Tang N, et al., Early risk stratification of patients with major trauma requiring massive blood transfusion. Resuscitation 2011; 82: 724-729.
33. Perkins JG, Andrew P, Spinella PC, Blackbourne LH, Grathwohl KW, Repine TB, et al., An evaluation of the impact of apheresis platelets used in the setting of massively transfused trauma patients. J Trauma 2009; 66: S77-S85.