메뉴 건너뛰기




Volumn 16, Issue 4, 2011, Pages 603-606

Emerging pharmacotherapy of tinnitus

Author keywords

Animal models; Anticonvulsants; Antidepressants; Anxiolytics; Auditory system; GABA; Glutamate; Hearing; Inner ear; NMDA; Pain; Phantom perception; Randomized clinical trials

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; AM 101; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIDIURETIC AGENT; ANTIHISTAMINIC AGENT; ANXIOLYTIC AGENT; BCG 492A; CALCIUM CHANNEL BLOCKING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CILOSTAZOL; CLONAZEPAM; DEXAMETHASONE; FLINDOKALNER; FLUPENTIXOL; GABAPENTIN; MELITRACEN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NERAMEXANE; NEUROLEPTIC AGENT; OTO 104; PAROXETINE; PLACEBO; SODIUM CHANNEL BLOCKING AGENT; TAURINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VESTIPITANT; VIGABATRIN;

EID: 84555191744     PISSN: 14728214     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728214.2011.644273     Document Type: Review
Times cited : (12)

References (23)
  • 1
    • 77955501743 scopus 로고    scopus 로고
    • Prevalence and characteristics of tinnitus among US adults
    • Shargorodsky J, Curhan GC, Farwell WR. Prevalence and characteristics of tinnitus among US adults. Am J Med 2010;123(8):711-18
    • (2010) Am J Med , vol.123 , Issue.8 , pp. 711-718
    • Shargorodsky, J.1    Curhan, G.C.2    Farwell, W.R.3
  • 2
    • 79960449693 scopus 로고    scopus 로고
    • A review of tinnitus symptoms beyond 'ringing in the ears': A call to action
    • Langguth B. A review of tinnitus symptoms beyond 'ringing in the ears': a call to action. Curr Med Res Opin 2011;27(8):1635-43
    • (2011) Curr Med Res Opin , vol.27 , Issue.8 , pp. 1635-1643
    • Langguth, B.1
  • 4
    • 78149489680 scopus 로고    scopus 로고
    • Ringing ears: The neuroscience of tinnitus
    • Roberts LE, Eggermont JJ, Caspary DM, et al. Ringing ears: the neuroscience of tinnitus. J Neurosci 2010;30(45):14972-9
    • (2010) J Neurosci , vol.30 , Issue.45 , pp. 14972-14979
    • Roberts, L.E.1    Eggermont, J.J.2    Caspary, D.M.3
  • 5
    • 80052584469 scopus 로고    scopus 로고
    • Homeostatic plasticity drives tinnitus perception in an animal model
    • Yang S, Weiner BD, Zhang LS, et al. Homeostatic plasticity drives tinnitus perception in an animal model. Proc Natl Acad Sci USA 2011;108(36):14974-9
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.36 , pp. 14974-14979
    • Yang, S.1    Weiner, B.D.2    Zhang, L.S.3
  • 6
    • 77953924882 scopus 로고    scopus 로고
    • Tuning out the noise: Limbic-auditory interactions in tinnitus
    • Rauschecker JP, Leaver AM, Muhlau M. Tuning out the noise: limbic-auditory interactions in tinnitus. Neuron 2010;66(6):819-26
    • (2010) Neuron , vol.66 , Issue.6 , pp. 819-826
    • Rauschecker, J.P.1    Leaver, A.M.2    Muhlau, M.3
  • 7
    • 79957689803 scopus 로고    scopus 로고
    • Phantom percepts: Tinnitus and pain as persisting aversive memory networks
    • De Ridder D, Elgoyhen AB, Romo R, Langguth B. Phantom percepts: Tinnitus and pain as persisting aversive memory networks. Proc Natl Acad Sci USA 2011;108(20):8075-80
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.20 , pp. 8075-8080
    • De Ridder, D.1    Elgoyhen, A.B.2    Romo, R.3    Langguth, B.4
  • 8
    • 80052741589 scopus 로고    scopus 로고
    • Inhibitory neurotransmission in animal models of tinnitus: Maladaptive plasticity
    • Wang H, Brozoski TJ, Caspary DM. Inhibitory neurotransmission in animal models of tinnitus: maladaptive plasticity. Hear Res 2011;279(1-2):111-17
    • (2011) Hear Res , vol.279 , Issue.1-2 , pp. 111-117
    • Wang, H.1    Brozoski, T.J.2    Caspary, D.M.3
  • 9
    • 77955106753 scopus 로고    scopus 로고
    • The tinnitus research initiative (TRI) database: A new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome
    • Landgrebe M, Zeman F, Koller M, et al. The Tinnitus Research Initiative (TRI) database: a new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome. BMC Med Inform Decis Mak 2010;10:42
    • (2010) BMC Med Inform Decis Mak , vol.10 , pp. 42
    • Landgrebe, M.1    Zeman, F.2    Koller, M.3
  • 10
    • 79956300057 scopus 로고    scopus 로고
    • Mice with behavioral evidence of tinnitus exhibit dorsal cochlear nucleus hyperactivity because of decreased gabaergic inhibition
    • Middleton JW, Kiritani T, Pedersen C, et al. Mice with behavioral evidence of tinnitus exhibit dorsal cochlear nucleus hyperactivity because of decreased GABAergic inhibition. Proc Natl Acad Sci USA 2011;108(18):7601-6
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.18 , pp. 7601-7606
    • Middleton, J.W.1    Kiritani, T.2    Pedersen, C.3
  • 11
    • 78649878918 scopus 로고    scopus 로고
    • The effect of SUPPL.emental dietary taurine on tinnitus and auditory discrimination in an animal model
    • Brozoski TJ, Caspary DM, Bauer CA, Richardson BD. The effect of SUPPL.emental dietary taurine on tinnitus and auditory discrimination in an animal model. Hear Res 2010;270(1-2):71-80
    • (2010) Hear Res , vol.270 , Issue.1-2 , pp. 71-80
    • Brozoski, T.J.1    Caspary, D.M.2    Bauer, C.A.3    Richardson, B.D.4
  • 12
    • 79952269348 scopus 로고    scopus 로고
    • Physiological activation of cholinergic inputs controls associative synaptic plasticity via modulation of endocannabinoid signaling
    • Zhao Y, Tzounopoulos T. Physiological activation of cholinergic inputs controls associative synaptic plasticity via modulation of endocannabinoid signaling. J Neurosci 2011;31(9):3158-68
    • (2011) J Neurosci , vol.31 , Issue.9 , pp. 3158-3168
    • Zhao, Y.1    Tzounopoulos, T.2
  • 13
    • 77955768983 scopus 로고    scopus 로고
    • The effects of the synthetic cannabinoid receptor agonists, win55,212-2 and cp55,940, on salicylate-induced tinnitus in rats
    • Zheng Y, Stiles L, Hamilton E, et al. The effects of the synthetic cannabinoid receptor agonists, WIN55,212-2 and CP55,940, on salicylate-induced tinnitus in rats. Hear Res 2010;268(1-2):145-50
    • (2010) Hear Res , vol.268 , Issue.1-2 , pp. 145-150
    • Zheng, Y.1    Stiles, L.2    Hamilton, E.3
  • 14
    • 80053053909 scopus 로고    scopus 로고
    • Effects of the potassium ion channel modulators bms-204352 maxipost and its r-enantiomer on salicylate-induced tinnitus in rats
    • Lobarinas E, by-Brown W, Stolzberg D, et al. Effects of the potassium ion channel modulators BMS-204352 Maxipost and its R-enantiomer on salicylate-induced tinnitus in rats. Physiol Behav 2011;104(5):873-9
    • (2011) Physiol Behav , vol.104 , Issue.5 , pp. 873-879
    • Lobarinas, E.1    By-Brown, W.2    Stolzberg, D.3
  • 15
    • 78650735047 scopus 로고    scopus 로고
    • Oto-104: A sustained-release dexamethasone hydrogel for the treatment of otic disorders
    • Piu F, Wang X, Fernandez R, et al. OTO-104: a sustained-release dexamethasone hydrogel for the treatment of otic disorders. Otol Neurotol 2011;32(1):171-9
    • (2011) Otol Neurotol , vol.32 , Issue.1 , pp. 171-179
    • Piu, F.1    Wang, X.2    Fernandez, R.3
  • 16
    • 79960004946 scopus 로고    scopus 로고
    • A randomized, controlled study comparing the effects of vestipitant or vestipitant and paroxetine combination in subjects with tinnitus
    • Roberts C, Inamdar A, Koch A, et al. A randomized, controlled study comparing the effects of vestipitant or vestipitant and paroxetine combination in subjects with tinnitus. Otol Neurotol 2011;32(5):721-7
    • (2011) Otol Neurotol , vol.32 , Issue.5 , pp. 721-727
    • Roberts, C.1    Inamdar, A.2    Koch, A.3
  • 17
    • 79551545294 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of neramexane in patients with moderate to severe subjective tinnitus
    • Suckfuell M, Althaus M, Ellers-Lenz B, et al. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of neramexane in patients with moderate to severe subjective tinnitus. BMC Ear Nose Throat Disord 2011;11(1):1
    • (2011) BMC Ear Nose Throat Disord , vol.11 , Issue.1 , pp. 1
    • Suckfuell, M.1    Althaus, M.2    Ellers-Lenz, B.3
  • 18
    • 84855723943 scopus 로고    scopus 로고
    • Available from http://clinicaltrials.gov/ct2/show/NCT00772980, http://clinicaltrials. gov/ct2/show/NCT00827008
    • Neramexane: Clin Trial. Available from: http://clinicaltrials.gov/ct2/ show/NCT00739635, http://clinicaltrials.gov/ct2/show/NCT00772980, http://clinicaltrials. gov/ct2/show/NCT00827008 2011
    • (2011) Neramexane Clin Trial
  • 19
    • 84855745478 scopus 로고    scopus 로고
    • Available from
    • BGG492A Clin Trial. Available from: http://clinicaltrials.gov/ct2/show/ NCT01302873. 2011
    • (2011) BGG492A Clin Trial
  • 20
    • 84855733224 scopus 로고    scopus 로고
    • Available from
    • Cilostazol Clin Trial. Available from: http://clinicaltrials.gov/ct2/ show/NCT01378650. 2011
    • (2011) Cilostazol Clin Trial
  • 21
    • 79957998101 scopus 로고    scopus 로고
    • Administration of the combination clonazepam-Deanxit as treatment for tinnitus
    • Meeus O, De RD, Van de HP. Administration of the combination clonazepam-Deanxit as treatment for tinnitus. Otol Neurotol 2011;32(4):701-9
    • (2011) Otol Neurotol , vol.32 , Issue.4 , pp. 701-709
    • Meeus, O.1    De, R.D.2    Van De, H.P.3
  • 22
    • 78651558187 scopus 로고    scopus 로고
    • Safety of intratympanic injection of am-101 in patients with acute inner ear tinnitus
    • Muehlmeier G, Biesinger E, Maier H. Safety of Intratympanic Injection of AM-101 in Patients with Acute Inner Ear Tinnitus. Audiol Neurootol 2011;16(6):388-97
    • (2011) Audiol Neurootol , vol.16 , Issue.6 , pp. 388-397
    • Muehlmeier, G.1    Biesinger, E.2    Maier, H.3
  • 23
    • 84855742937 scopus 로고    scopus 로고
    • Available from
    • NST001 Clin Trial. Available from: http://clinicaltrials.gov/ct2/show/ NCT00957788 2011
    • (2011) NST001 Clin Trial


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.