Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates

ChemMedChem

Volumn 7, Issue 1, 2012, Pages 57-61

  Splith, Katrin ^b   Bergmann, Ralf ^c   Pietzsch, Jens ^c   Neundorf, Ines ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

Author keywords

Antitumor agents; Cell penetrating peptides; Drug delivery; Hypoxia; Tumor targeting

Indexed keywords

ANTINEOPLASTIC AGENT; BETA ALANINE; CARBOXYFLUORESCEIN; CARBOXYFLUORESCEIN SC18; CARBOXYFLUORESCEIN SC18 2 (2 NINITROIMIDAZOL 1 YL)ACETIC ACID; CELL PENETRATING PEPTIDE; DIAGNOSTIC AGENT; TETRAXETAN SC18; TETRAXETAN SC18 2 (2 NINITROIMIDAZOL 1 YL)ACETIC ACID; TRIFLUOROETHANOL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENDOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPOXEMIA; NONHUMAN; PRIORITY JOURNAL; RAT;

AMINO ACID SEQUENCE; ANIMALS; ANOXIA; CELL-PENETRATING PEPTIDES; DRUG DELIVERY SYSTEMS; METRONIDAZOLE; MOLECULAR SEQUENCE DATA; NEOPLASMS; RADIATION-SENSITIZING AGENTS; RATS; RATS, WISTAR;

EID: 84555186730     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100401     Document Type: Article

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