Association analyses of single nucleotide polymorphisms in bovine stearoyl-CoA desaturase and fatty acid synthase genes with fatty acid composition in commercial cross-bred beef steers

Animal Genetics

Volumn 43, Issue 1, 2012, Pages 93-97

  Li, C ^a,b   Aldai, N ^a,d   Vinsky, M ^a   Dugan, M E R ^a   McAllister, T A ^c  

^a LACOMBE RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c LETHBRIDGE RESEARCH CENTRE   (Canada)

^d Instituto de Ganadería de Montana   (Spain)

Author keywords

fatty acid composition in beef cattle; fatty acid synthase; single nucleotide polymorphism; Stearoyl CoA desaturase

Indexed keywords

ACYL COENZYME A DESATURASE; FATTY ACID; FATTY ACID SYNTHASE; UNSATURATED FATTY ACID;

ANIMAL; ARTICLE; CATTLE; GENETICS; MEAT;

ANIMALS; CATTLE; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; FATTY ACIDS, UNSATURATED; MEAT; STEAROYL-COA DESATURASE;

BOS; BOVINAE;

EID: 84555163810     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2011.02217.x     Document Type: Article

References (17)

1. Abe T., Saburi J., Hasebe H., Nakagawa T., Misumi S., Nade T., Nakajima H., Shoji N., Kobayashi M., &, Kobayashi E., (2009) Novel mutations of the FASN gene and their effect on fatty acid composition in Japanese Black beef. Biochemical Genetics 47, 397-411.
2. Aldai N., Dugan M.E., Kramer J.K., Mir P.S., &, McAllister T.A., (2008) Nonionophore antibiotics do not affect the trans-18:1 and conjugated linoleic acid composition in beef adipose tissue. Journal of Animal Science 86, 3522-32.
3. Barton L., Kott T., Bures D., Rehak D., Zahradkova R., &, Kottova B., (2010) The polymorphisms of stearoyl-CoA desaturase (SCD) and sterol regulatory element binding protein-1 (SREBP-1) genes and their association with the fatty acid profile of muscle and subcutaneous fat in Fleckvieh bulls. Meat Science 85, 15-20.
4. Canadian Council on Animal Care (CCAC). (1993) Guide to the Care and Use of Experimental Animals, Vol.1. (Edited by, E.D. Olfert, B.M. Cross, &, A.A. McWilliams,), CCAC, Ottawa, ON.
5. Chakravarty N., Gu Z., Chirala S.S., Wakil S.J., &, Quiocho F.A., (2004) Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proceedings of the National Academy of Sciences of the United States of America 101, 15567-72. (Pubitemid 39473528)
6. Falconer D.S., &, Mackay T.F.C., (1996) Introduction to Quantitative Genetics, 4th edn. Longman Scientific and Technical, New York, NY.
7. Jiang Z., Michal J.J., Tobey D.J., Daniels T.F., Rule D.C., &, Macneil M.D., (2008) Significant associations of stearoyl-CoA desaturase (SCD) gene with fat deposition and composition in skeletal muscle. International Journal of Biological Sciences 25, 345-51.
8. Jiang Z., Michal J.J., Chen J., et al. (2009) Discovery of novel genetic networks associated with 19 economically important traits in beef cattle. International Journal of Biological Sciences 29, 528-42.
9. Kim Y.C., &, Ntambi J.M., (1999) Regulation of stearoyl-CoA desaturase genes: role in cellular metabolism and preadipocyte differentiation. Biochemical and Biophysical Research Communications 266, 1-4. (Pubitemid 30028757)
10. Li C., Vinsky M., Aldai N., Osoro K., &, Dugan M.E.R., (2010) Associations of a bovine SCD SNP with fatty acid composition in concentrate-finished yearling bulls of different muscular hypertrophy genotypes. Proceedings of 9th World Congress on Genetics Applied to Livestock Production (WCGALP), Leipzig, Germany, 505.
11. Lin C.Y., &, Smith S., (1978) Properties of the thioesterase component obtained by limited trypsinization of the fatty acid synthetase multienzyme complex. The Journal of Biological Chemistry 253, 1954-62. (Pubitemid 8299522)
12. Ohsaki H., Tanaka A., Hoashi S., Sasazaki S., Oyama K., Taniguchi M., Mukai F., &, Mannen H., (2009) Effect of SCD and SREBP genotypes on fatty acid composition in adipose tissue of Japanese Black cattle herds. Animal Science Journal 80, 225-32.
13. SAS Institute Inc. (2001) SAS User's guide: Statistics. SAS for Windows, Version 8.2. SAS Institute, Inc., Cary, NC.
14. Taniguchi M., Utsugi T., Oyama K., Mannen H., Kobayashi M., Tanabe Y., Ogino A., &, Tsuji S., (2004) Genotype of stearoyl-CoA desaturase is associated with fatty acid composition in Japanese Black cattle. Mammalian Genome 15, 142-8. (Pubitemid 38147274)
15. Ulbricht T.L., &, Southgate D.A., (1991) Coronary heart disease: seven dietary factors. The Lancet 338, 985-92.
16. Zhang S., Knight T.J., Reecy J.M., &, Beitz D.C., (2008) DNA polymorphisms in bovine fatty acid synthase are associated with beef fatty acid composition. Animal Genetics 39, 62-70. (Pubitemid 351178362)
17. Zhang S., Knight T.J., Reecy J.M., Wheeler T.L., Shackelford S.D., Cundiff L.V., &, Beitz D.C., (2010) Associations of polymorphisms in the promoter I of bovine acetyl-CoA carboxylase-alpha gene with beef fatty acid composition. Animal Genetics 41, 417-20.