Quantitative histological analysis of SM22α (Transgelin) in an adriamycin-induced focal segmental glomerulosclerosis model

Nephron - Experimental Nephrology

Volumn 120, Issue 1, 2012, Pages

  Wang, Xingzhi ^a   Sakatsume, Minoru ^a   Sakamaki, Yuichi ^a   Inomata, Shigeru ^a   Yamamoto, Tadashi ^a   Narita, Ichiei ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Adriamycin nephropathy; Focal segmental glomerulosclerosis; Interstitial cell; Podocyte; SM22 ; Transgelin; Tubulointerstitium

Indexed keywords

DOXORUBICIN; MONOCLONAL ANTIBODY; TRANSGELIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; FOCAL GLOMERULOSCLEROSIS; GLOMERULUS; HISTOPATHOLOGY; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY DYSFUNCTION; LEYDIG CELL; MALE; MICROFILAMENT; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT;

ANIMALS; DISEASE MODELS, ANIMAL; DOXORUBICIN; EPITHELIAL CELLS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY GLOMERULUS; KIDNEY TUBULES; MALE; MICROFILAMENT PROTEINS; MICROSCOPY, IMMUNOELECTRON; MUSCLE PROTEINS; PODOCYTES; RATS; RATS, WISTAR;

EID: 84455205116     PISSN: None     EISSN: 16602129     Source Type: Journal    
DOI: 10.1159/000329664     Document Type: Article

References (26)

1. Lees-Miller JP, Heeley DH, Smillie LB: An abundant and novel protein of 22 kDa (SM22) is widely distributed in smooth muscles. Purification from bovine aorta. Biochem J 1987; 244:705-709.
2. Shapland C, Hsuan JJ, Totty NF, Lawson D: Purification and properties of transgelin: a transformation and shape change sensitive actin-gelling protein. J Cell Biol 1993; 121: 1065-1073. (Pubitemid 23154267)
3. Almendral JM, Santaren JF, Perera J, Zerial M, Bravo R: Expression, cloning and CDNA sequence of a fibroblast serum-regulated gene encoding a putative actin-associated protein (p27). Exp Cell Res 1989; 181: 518-530. (Pubitemid 19096416)
4. Duband JL, Gimona M, Scatena M, Sartore S, Small JV: Calponin and SM22 as differentiation markers of smooth muscle: spatiotempo-ral distribution during avian embryonic development. Differentiation 1993; 55:1-11.
5. Pearlstone JR, Weber M, Lees-Miller JP, Carpenter MR, Smillie LB: Amino acid sequence of chicken gizzard smooth muscle SM22a. J Biol Chem 1987; 262: 5985-5991.
6. Lawson D, Harrison M, Shapland C: Fibroblast transgelin and smooth muscle SM22a are the same protein, the expression of which is down-regulated in many cell lines. Cell Motil Cytoskeleton 1997; 38:250-257. (Pubitemid 27484089)
7. Assinder SJ, Stanton JA, Prasad PD: Transgelin: An actin-binding protein and tumour suppressor. Int J Biochem Cell Biol 2009; 41: 482-486.
8. Fu Y, Liu HW, Forsythe SM, Kogut P, Mc-Conville JF, Halayko AJ, Camoretti-Merca-do B, Solway J: Mutagenesis analysis of human SM22: characterization of actin binding. J Appl Physiol 2000; 89: 1985-1990.
9. Zhang JC, Kim S, Helmke BP, Yu WW, Du KL, Lu MM, Strobeck M, Yu Q, Parmacek MS: Analysis of SM22a-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function. Mol Cell Biol 2001; 21: 1336-1344. (Pubitemid 32114981)
10. Feil S, Hofmann F, Feil R: SM22a modulates vascular smooth muscle cell phenotype during atherogenesis. Circ Res 2004; 94: 863-865. (Pubitemid 38490062)
11. Shields JM, Rogers-Graham K, Der CJ: Loss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent pathways. J Biol Chem 2002; 277:9790-9799. (Pubitemid 34968082)
12. Wulfkuhle JD, Sgroi DC, Krutzsch H, McLean K, McGarvey K, Knowlton M, Chen S, Shu H, Sahin A, Kurek R, Wallwiener D, Merino MJ, Petricoin EF 3rd, Zhao Y, Steeg PS: Proteomics of human breast ductal carcinoma in situ. Cancer Res 2002; 62: 6740-6749. (Pubitemid 35364146)
13. Yu H, Konigshoff M, Jayachandran A, Hand-ley D, Seeger W, Kaminski N, Eickelberg O: Transgelin is a direct target of TGF-fV Smad3-dependent epithelial cell migration in lung fibrosis. FASEB J 2008; 22:1778-1789. (Pubitemid 351811455)
14. Nair RR, Solway J, Boyd DD: Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collage-nase (MMP-9) expression. J Biol Chem 2006; 281: 26424-26436. (Pubitemid 44401851)
15. Zhao L, Wang H, Deng YJ, Wang S, Liu C, Jin H, Ding YQ: Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients. Mod Pathol 2009; 22: 786-796.
16. Schnaper HW: Idiopathic focal segmental glomerulosclerosis. Semin Nephrol 2003; 23: 183-193. (Pubitemid 36397100)
17. O'Donnell MP, Michels L, Kasiske B, Raij L, Keane WF: Adriamycin-induced chronic proteinuria: a structural and functional study. J Lab Clin Med 1985; 106: 62-67. (Pubitemid 16046644)
18. Ogawa A, Sakatsume M, Wang X, Sakamaki Y, Tsubata Y, Alchi B, Kuroda T, Kawachi H, Narita I, Shimizu F, Gejyo F: SM22a: the novel phenotype marker of injured glomerular epithelial cells in anti-glomerular basement membrane nephritis. Nephron Exp Nephrol 2007; 106:e77-e87. (Pubitemid 47026176)
19. Kaneko Y, Sakatsume M, Xie Y, Kuroda T, Igashima M, Narita I, Gejyo F: Macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritis. J Immunol 2003; 170: 3377-3385. (Pubitemid 36302217)
20. Inomata S, Sakatsume M, Sakamaki Y, Wang X, Goto S, Yamamoto T, Gejyo F, Narita I: Expression of SM22a (transgelin) in glomerular and interstitial renal injury. Nephron Exp Nephrol 2010; 117:e104-e113.
21. Saga D, Sakatsume M, Ogawa A, Tsubata Y, Kaneko Y, Kuroda T, Sato F, Ajiro J, Kondo D, Miida T, Narita I, Gejyo F: Bezafibrate suppresses rat antiglomerular basement membrane crescentic glomerulonephritis. Kidney Int 2005; 67:1821-1829. (Pubitemid 40577717)
22. Tsubata Y, Sakatsume M, Ogawa A, Alchi B, Kaneko Y, Kuroda T, Kawachi H, Narita I, Yamamoto T, Gejyo F: Expression of allograft inflammatory factor-1 in kidneys: a novel molecular component of podocyte. Kidney Int 2006; 70: 1948-1954. (Pubitemid 44863383)
23. Kuzuhara T, Kise D, Shirakawa Y, Sasada K, Suganuma M, Fujiki H: Generation of mouse monoclonal antibody against (-)-epigallo-catechin gallate. Biol Pharm Bull 2008; 31: 816-819. (Pubitemid 351731967)
24. Kuhara M, Yoshino T, Shiokawa M, Okabe T, Mizoguchi S, Yabuhara A, Takeyama H, Matsunaga T: Magnetic separation of human podocalyxin-like protein 1 (hPCLP1)-posi-tive cells from peripheral blood and umbilical cord blood using anti-hPCLP1 monoclonal antibody and protein a expressed on bacterial magnetic particles. Cell Struct Funct 2009; 34: 23-30.
25. Tyagi P, Chen X, Hayashi Y, Yoshimura N, Chancellor MB, de Miguel F: Proteomic investigation on chronic bladder irritation in the rat. Urology 2008; 71: 536-540. (Pubitemid 351374731)
26. Shirato I, Sakai T, Kimura K, Tomino Y, Kriz W: Cytoskeletal changes in podocytes associated with foot process effacement in Masugi nephritis. Am J Pathol 1996; 148:1283-1296. (Pubitemid 26111083)