Nanotube action between human mesothelial cells reveals novel aspects of inflammatory responses

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Ranzinger, Julia ^a   Rustom, Amin ^a,b   Abel, Marcus ^a,b   Leyh, Julia ^a   Kihm, Lars ^a   Witkowski, Margarete ^c   Scheurich, Peter ^c   Zeier, Martin ^a   Schwenger, Vedat ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAX PLANCK INSTITUTE FOR INTELLIGENT SYSTEMS   (Germany)

^c UNIVERSITY OF STUTTGART   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CHOLESTEROL; FILIPIN; NANOTUBE; RAPAMYCIN; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

ACTIN FILAMENT; ARTICLE; CELL COUNT; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; FILOPODIUM; HUMAN; HUMAN CELL; MESOTHELIUM CELL; PERITONEAL DIALYSIS; PERITONITIS; UREMIA; EPITHELIUM; FLUORESCENCE MICROSCOPY; IMMUNOLOGY; INFLAMMATION; LYMPHOCYTE ACTIVATION; MICROINJECTION; PATHOLOGY; PERITONEAL CAVITY; PHYSIOLOGY; SCANNING ELECTRON MICROSCOPY; T LYMPHOCYTE;

EPITHELIUM; HUMANS; INFLAMMATION; LYMPHOCYTE ACTIVATION; MICROINJECTIONS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; NANOTUBES; PERITONEAL CAVITY; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84455169890     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029537     Document Type: Article

References (26)

1. Flessner MF, Credit K, Henderson K, Vanpelt HM, Potter R, et al. (2007) Peritoneal changes after exposure to sterile solutions by catheter. J Am Soc Nephrol 18: 2294-2302.
2. Flessner MF, Credit K, Richardson K, Potter R, Li X, et al. (2010) Peritoneal inflammation after twenty-week exposure to dialysis solution: effect of solution versus catheter-foreign body reaction. Perit Dial Int 30: 284-293.
3. Witowski J, Korybalska K, Wisniewska J, Breborowicz A, Gahl GM, et al. (2000) Effect of glucose degradation products on human peritoneal mesothelial cell function. J Am Soc Nephrol 11: 729-739.
4. Wang X, Veruki ML, Bukoreshtliev NV, Hartveit E, Gerdes HH, (2010) Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels. Proc Natl Acad Sci U S A 107: 17194-17199.
5. Hurtig J, Chiu DT, Onfelt B, (2011) Intercellular nanotubes: insights from imaging studies and beyond. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2: 260-276.
6. Dubey GP, Ben-Yehuda S, (2011) Intercellular nanotubes mediate bacterial communication. Cell 144: 590-600.
7. Sowinski S, Jolly C, Berninghausen O, Purbhoo MA, Chauveau A, et al. (2008) Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nat Cell Biol 10: 211-219.
8. Chauveau A, Aucher A, Eissmann P, Vivier E, Davis DM, (2010) Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells. Proc Natl Acad Sci U S A 107: 5545-5550.
9. Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, et al. (2009) M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex. Nat Cell Biol 11: 1427-1432.
10. Chinnery HR, Pearlman E, McMenamin PG, (2008) Cutting edge: Membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 180: 5779-5783.
11. Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH, (2004) Nanotubular highways for intercellular organelle transport. Science 303: 1007-1010.
12. Abel MP, Riese SR, Schlicker O, Bukoreshtliev NV, Gerdes HH, et al. (2011) Microstructured platforms to study nanotube-mediated long-distance cell-to-cell connections. Biointerphases 6: 22-31.
13. Wang Y, Cui J, Sun X, Zhang Y, (2011) Tunneling-nanotube development in astrocytes depends on p53 activation. Cell Death Differ 18: 732-742.
14. Koukouritaki SB, Vardaki EA, Papakonstanti EA, Lianos E, Stournaras C, et al. (1999) TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase. Mol Med 5: 382-392.
15. Yonemura Y, Endou Y, Nojima M, Kawamura T, Fujita H, et al. (1997) A possible role of cytokines in the formation of peritoneal dissemination. Int J Oncol 11: 349-358.
16. Puls A, Eliopoulos AG, Nobes CD, Bridges T, Young LS, et al. (1999) Activation of the small GTPase Cdc42 by the inflammatory cytokines TNF(alpha) and IL-1, and by the Epstein-Barr virus transforming protein LMP1. J Cell Sci 112 (Pt 17): 2983-2992.
17. Bukoreshtliev NV, Wang X, Hodneland E, Gurke S, Barroso JF, et al. (2009) Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells. FEBS Lett 583: 1481-1488.
18. Gousset K, Zurzolo C, (2009) Tunnelling nanotubes: a highway for prion spreading? Prion 3: 94-98.
19. Eugenin EA, Gaskill PJ, Berman JW, (2009) Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: a potential mechanism for intercellular HIV trafficking. Cell Immunol 254: 142-148.
20. Pewzner-Jung Y, Brenner O, Braun S, Laviad EL, Ben-Dor S, et al. (2010) A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. J Biol Chem 285: 10911-10923.
21. Aarons CB, Cohen PA, Gower A, Reed KL, Leeman SE, et al. (2007) Statins (HMG-CoA reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytic activity. Ann Surg 245: 176-184.
22. Haslinger B, Goedde MF, Toet KH, Kooistra T, (2002) Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering. Kidney Int 62: 1611-1619.
23. Haslinger B, Kleemann R, Toet KH, Kooistra T, (2003) Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells. Kidney Int 63: 2065-2074.
24. Araujo FA, Rocha MA, Ferreira MA, Campos PP, Capettini LS, et al. (2011) Implant-induced intraperitoneal inflammatory angiogenesis is attenuated by fluvastatin. Clin Exp Pharmacol Physiol 38: 262-268.
25. Lee JE, Oh KH, Choi KH, Kim SB, Kim YS, et al. (2011) Statin therapy is associated with improved survival in incident peritoneal dialysis patients: propensity-matched comparison. Nephrol Dial Transplant.
26. Kumar S, Raftery M, Yaqoob M, Fan SL, (2007) Anti-inflammatory effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors (statins) in peritoneal dialysis patients. Perit Dial Int 27: 283-287.