Acute glucocorticoid administration rapidly suppresses basal and stress-induced hypothalamo-pituitary-adrenal axis activity

Endocrinology

Volumn 153, Issue 1, 2012, Pages 200-211

  Andrews, Marcus H ^a   Wood, Susan A ^a   Windle, Richard J ^b   Lightman, Stafford L ^a   Ingram, Colin D ^c  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; DEXAMETHASONE; GLUCOCORTICOID; METHYLPREDNISOLONE SODIUM SUCCINATE; MIFEPRISTONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CIRCADIAN RHYTHM; CORTICOSTERONE RELEASE; DOSE RESPONSE; DRUG EFFECT; FEMALE; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MENTAL STRESS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CIRCADIAN RHYTHM; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DEXAMETHASONE; FEEDBACK, PHYSIOLOGICAL; FEMALE; GLUCOCORTICOIDS; HORMONE ANTAGONISTS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; METHYLPREDNISOLONE; MIFEPRISTONE; PITUITARY-ADRENAL SYSTEM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; STRESS, PHYSIOLOGICAL;

EID: 84455160754     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1434     Document Type: Article

References (53)

1. Jingami H, Matsukura S, Numa S, Imura H 1985 Effects of adrenalectomy and dexamethasone administration on the level of prepro-corticotropin-releasing factor messenger ribonucleic acid (mRNA) in the hypothalamus and adrenocorticotropin/β-lipotropin precursor mRNA in the pituitary in rats. Endocrinology 117:1314-1320 (Pubitemid 15238105)
2. Kovács KJ, Mezey E 1987 Dexamethasone inhibits corticotropinreleasing factor gene expression in the rat paraventricular nucleus. Neuroendocrinology 46:365-368 (Pubitemid 17144487)
3. Drouin J, Sun YL, Nemer M 1989 Glucocorticoid repression of pro-opiomelanocortin gene transcription. J Steroid Biochem 34: 63-69 (Pubitemid 20061767)
4. Lightman SL, Young 3rd WS 1989 Influence of steroids on the hypothalamic corticotropin-releasing factor and preproenkephalin mRNA responses to stress. Proc Natl Acad Sci USA 86:4306-4310 (Pubitemid 19154784)
5. Nakai Y, Usui T, Tsukada T, Takahashi H, Fukata J, Fukushima M, Senoo K, Imura H 1991 Molecular mechanisms of glucocorticoid inhibition of human proopiomelanocortin gene transcription. J Steroid Biochem Mol Biol 40:301-306
6. Ma XM, Aguilera G 1999 Differential regulation of corticotropin-releasing hormone and vasopressin transcription by glucocorticoids. Endocrinology 140:5642-5650 (Pubitemid 30645352)
7. Dallman MF 2005 Fast glucocorticoid actions on brain: back to the future. Front Neuroendocrinol 26:103-108 (Pubitemid 41772649)
8. Spiga F, Harrison LR, Wood SA, MacSweeney CP, Thomson FJ, Craighead M, Grassie M, Lightman SL 2008 Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release. J Endocrinol 196:323-330 (Pubitemid 351298517)
9. Atkinson HC, Wood SA, Castrique ES, Kershaw YM, Wiles CCR, Lightman SL 2008 Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary- adrenal axis via the mineralocorticoid receptor. Am J Physiol 294:E1011-E1022
10. Russell GM, Henley DE, Leendertz J, Douthwaite JA, Wood SA, Stevens A, Woltersdorf WW, PeetersBWMM,Ruigt GSF, White A, Veldhuis JD, Lightman SL 2010 Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary- adrenal ultradian activity in healthy males. J Neurosci 30:6106-6115
11. Cole MA, Kim PJ, Kalman BA, Spencer RL 2000 Dexamethasone suppression of corticosteroid secretion: evaluation of the site of action by receptor measures and functional studies. Psychoneuroendocrinology 25:151-167 (Pubitemid 29525388)
12. Hinz B, Hirschelmann R 2000 Rapid non-genomic feedback effects of glucocorticoids on CRF-induced ACTH secretion in rats. Pharm Res 17:1273-1277
13. Sapolsky RM, Krey LC, McEwen BS 1984 Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response. Proc Natl Acad Sci USA 81:6174-6177 (Pubitemid 15220802)
14. Ginsberg AB, Campeau S, Day HE, Spencer RL 2003 Acute glucocorticoid pretreatment suppresses stress-induced hypothalamic-pituitary- adrenal axis hormone secretion and expression of corticotropin-releasing hormone hnRNA but does not affect c-fos mRNA or Fos protein expression in the paraventricular nucleus of the hypothalamus. J Neuroendocrinol 15:1075-1083 (Pubitemid 37369169)
15. Jacobson L, Sapolsky R 1991 The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis. Endocr Rev 12:118-134
16. Feldman S, Weidenfeld J 1995 Neural mechanisms involved in the corticosteroid feedback effects on the hypothalamo-pituitary-adrenocortical axis. Prog Neurobiol 45:129-141
17. Herman JP, Ostrander MM, Mueller NK, Figueiredo H 2005 Limbic system mechanisms of stress regulation: Hypothalamo-pituitary- adrenocortical axis. Prog Neuro-Psychopharmacol Biol Psychiatry 29:1201-1213 (Pubitemid 41674635)
18. Keenan DM, Licinio J, Veldhuis JD 2001 A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis. Proc Natl Acad Sci USA 98:4028-4033 (Pubitemid 32249892)
19. Walker JJ, Terry JR, Lightman SL 2010 Origin of ultradian pulsatility in the hypothalamic-pituitary-adrenal axis. Proc R Soc B 277: 1627-1633
20. Abe K, Critchlow V 1977 Effects of corticosterone, dexamethasone and surgical isolation of the medial basal hypothalamus on rapid feedback control of stress-induced corticotropin secretion in female rats. Endocrinology 101:498-505 (Pubitemid 8162321)
21. Keller-WoodM1990 Fast feedback control of canine corticotropin by cortisol. Endocrinology 126:1959-1966
22. Young EA, Akana S, Dallman MF 1990 Decreased sensitivity to glucocorticoid fast feedback in chronically stressed rats. Neuroendocrinology 51:536-542 (Pubitemid 20152649)
23. Nolan LA, Windle RJ, Wood SA, Kershaw YM, Lunness HR, Lightman SL, Ingram CD, Levy A 2000 Chronic iodine deprivation attenuates stress-induced and diurnal variation in corticosterone secretion in female Wistar rats. J Neuroendocrinol 12:1149-1159
24. Thrivikraman KV, Nemeroff CB, Plotsky PM 2000 Sensitivity of glucocorticoid-mediated fast-feedback regulation of the hypothalamic- pituitary-adrenal axis is dependent upon stressor specific neurocircuitry. Brain Res 870:87-101 (Pubitemid 30408407)
25. Spiga F, Harrison LR, Wood SA, Atkinson HC, MacSweeney CP, Thomson F, Craighead M, Grassie M, Lightman SL 2007 Effect of the glucocorticoid receptor antagonist Org 34850 on basal and stress-induced corticosterone secretion. J Neuroendocrinol 19:891-900 (Pubitemid 47555234)
26. Rotsztejn W, Lalonde J, Normand M, Fortier C 1975 Feedback inhibition of adrenocorticotropin release by corticosterone infusions in the adrenalectomised rat. Can J Physiol Pharmacol 53:475-478
27. Cowan JS, Windle WJ 1978 Progressive suppression of adrenocorticotropin secretion in resting adrenalectomized dogs by low stepwise infusions of cortisol. Endocrinology 103:1173-1182 (Pubitemid 9048003)
28. Cowan JS, Layberry RA 1983 Feedback suppression of ACTH secretion by cortisol in dogs: Lags after large signals equal those following very small signals. Can J Physiol Pharmacol 61:1281-1288 (Pubitemid 14222173)
29. Reader SC, Alaghband-Zadeh J, Daly JR, Robertson WR 1982 Negative, rate-sensitive feedback effects on adrenocorticotrophin secretion by cortisol in normal subjects. J Endocrinol 92:443-448 (Pubitemid 12183724)
30. Young EA, Haskett RF, Murphy-Weinberg V, Watson SJ, Akil H 1991 Loss of glucocorticoid fast feedback in depression. Arch Gen Psychiatry 48:693-699
31. Goodwin GM, Muir WJ, Seckl JR, Bennie J, Carroll S, Dick H, Fink G 1992 The effects of cortisol infusion upon hormone secretion from the anterior pituitary and subjective mood in depressive illness and in controls. J Affect Disord 26:73-83
32. Kellner M, Holsboer F, Heuser I 1995 Intermediate glucocorticoid feedback of corticotropin secretion in patients with major depression. Psychiatry Res 59:157-160 (Pubitemid 26024513)
33. Posener JA, Schildkraut JJ, Williams GH, Schatzberg AF 1997 Cortisol feedback effects on plasma corticotropin levels in healthy subjects. Psychoneuroendocrinology 22:169-176 (Pubitemid 27293622)
34. Boscaro M, Paoletta A, Scarpa E, Barzon L, Fusaro P, Fallo F, Sonino N 1998 Age-related changes in glucocorticoid fast feedback inhibition of adrenocorticotropin in man. J Clin Endocrinol Metab 83:1380-1383 (Pubitemid 28496423)
35. Boudinot FD, Jusko WJ 1986 Dose-dependent pharmacokinetics of prednisolone in normal and adrenalectomized rats. J Pharmacokinet Biopharm 14:453-467 (Pubitemid 17201333)
36. Seale JV,Wood SA, Atkinson HC, Bate E, Lightman SL, Ingram CD, Jessop DS, Harbuz MS 2004 Gonadectomy reverses the sexually diergic patterns of circadian and stress-induced hypothalamic-pituitary- adrenal axis activity in male and female rats. J Neuroendocrinol 16:516-524 (Pubitemid 38878283)
37. Windle RJ, Wood SA, Shanks N, Lightman SL, Ingram CD 1998 Ultradian rhythm of basal corticosterone release in the female rat: dynamic interaction with the response to acute stress. Endocrinology 139:443-450 (Pubitemid 28513187)
38. Lightman SL, Windle RJ, Julian MD, Harbuz MS, Shanks N, Wood SA, Kershaw YM, Ingram CD 2000 Significance of pulsatility in the HPA axis. Novartis Foundation Symp 227:244-257
39. Windle RJ,WoodSA, KershawYM,Lightman SL, Ingram CD 2010 Reduced stress responsiveness in pregnancy: Relationship with pattern of forebrain c-fos mRNA expression. Brain Res 1358:102-109
40. Jones MT, Brush FR, Neame RL 1972 Characteristics of fast feedback control of corticotrophin release by corticosteroids. J Endocrinol 55:489-497
41. Jones MT, Hillhouse EW, Burden JL 1977 Dynamics and mechanisms of corticosteroid feedback at the hypothalamus and anterior pituitary gland. J Endocrinol 73:405-417 (Pubitemid 8118841)
42. Kaneko M, Hiroshige T 1978 Fast, rate-sensitive corticosteroid negative feedback during stress. Am J Physiol 234:R39-R45 (Pubitemid 9133195)
43. Krishnan KR, Ritchie JC, Manepalli AN, Saunders W, Li SW, Venkataraman S, Nemeroff CB, Carroll BJ 1991 Fast feedback regulation of ACTH by cortisol. Prog Neuropsychopharmacol Biol Psychiatry 15:523-529
44. Hess GD, Riegle GD 1972 Effects of chronic ACTH stimulation on adrenocortical function in young and aged rats. Am J Physiol 222: 1458-1461
45. Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW 2003 Structural determinants of P-glycopro-tein-mediated transport of glucocorticoids. Pharm Res 20:1794-1803 (Pubitemid 37449453)
46. Livesey JH, Evans MJ, Mulligan R, Donald RA 2000 Interactions of CRH, AVP and cortisol in the secretion of ACTH from perifused equine anterior pituitary cells: "permissive" roles for cortisol and CRH. Endocr Res 26:445-463
47. Grossmann C, Scholz T, Rochel M, Bumke-Vogt C, Oelkers W, Pfeiffer AF, Diederich S, Bahr V 2004 Transactivation via thehuman glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties. Eur J Endocrinol 151:397-406 (Pubitemid 39307329)
48. Peterson ME, Graves TK 1988 Effects of low dosages of intravenous dexamethasone on serum cortisol concentrations in the normal cat. Res Vet Sci 44:38-40 (Pubitemid 18034536)
49. Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, Pooley JR, Johnson TA, Voss TC, Lightman SL, Hager GL 2009 Ultradian hormone stimulation induces glucocorticoid receptor- mediated pulses of gene transcription. Nat Cell Biol 11:1093-1102
50. Osterlund C, Spencer RL 2011 Corticosterone pretreatment suppresses stress-induced hypothalamic-pituitary-adrenal axis activity via multiple actions that vary with time, site of action and de novo protein synthesis. J Endocrinol 208:311-322
51. Weidenfeld J, Feldman S 1993 Glucocorticoid feedback regulation of adrenocortical responses to neural stimuli: role of CRF-41 and corticosteroid type I and type II receptors. Neuroendocrinology 58: 49-56 (Pubitemid 23279070)
52. Karssen AM, Meijer OC, van der Sandt IC, De Boer AG, De Lange EC, De Kloet ER 2002 The role of the efflux transporter P-glycoprotein in brain penetrance of prednisolone. J Endocrinol 175:251-260 (Pubitemid 35276604)
53. Evanson NK, Tasker JG, Hill MN,Hillard CJ, Herman JP 2010 Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signalling. Endocrinology 151:4811-4819