Low-level lifetime exposure to cadmium decreases skeletal mineralization and enhances bone loss in aged rats

Bone

Volumn 35, Issue 5, 2004, Pages 1180-1191

  Brzoska M M ^a   Moniuszko Jakoniuk, J ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Bone loss; Bone mineral status; Bone turnover; Cadmium; Female rats

Indexed keywords

ALKALINE PHOSPHATASE; CADMIUM; COLLAGEN TYPE 1; OSTEOCALCIN; TELOPEPTIDE;

AGING; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE DISEASE; BONE GROWTH; BONE METABOLISM; BONE MINERAL; BONE MINERALIZATION; CALCIUM BLOOD LEVEL; CALCIUM URINE LEVEL; CONTROLLED STUDY; DENSITOMETRY; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME CHEMISTRY; EXPERIMENTAL MODEL; FEMALE; FEMUR; LONG TERM EXPOSURE; LUMBAR SPINE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPENIA; OSTEOPOROSIS; POLLUTION; RAT; RISK FACTOR; SKELETON; TRABECULAR BONE;

ALKALINE PHOSPHATASE; ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE DISEASES, METABOLIC; BONE REMODELING; CADMIUM; CALCIFICATION, PHYSIOLOGIC; CALCIUM; COLLAGEN; COLLAGEN TYPE I; DRINKING; EATING; ENVIRONMENTAL EXPOSURE; FEMALE; FEMUR; LUMBAR VERTEBRAE; OSTEOPOROSIS; PEPTIDES; RANDOM ALLOCATION; RATS; RATS, WISTAR; TIME FACTORS;

EID: 8444249612     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.07.010     Document Type: Article

References (48)

1. K. Aoshima, J. Fan, Y. Cai, T. Katoh, H. Teranishi, and M. Kasuya Assessment of bone metabolism in cadmium-induced renal tubular dysfunction by measurements of biochemical markers Toxicol. Lett. 136 2003 183 192
2. T. Kjellström Mechanism and epidemiology of bone effects of cadmium IARC Sci. Publ. 118 1992 301 310
3. G. Nordberg, T. Jin, A. Bernard, S. Fierens, J.P. Buchet, and T. Ye Low bone density and renal dysfunction following environmental cadmium exposure in China Ambio 31 2002 478 481
4. H. Wang, G. Zhu, Y. Shi, S. Weng, T. Jin, and Q. Kong Influence of environmental cadmium exposure on forearm bone density J. Bone Miner. Res. 18 2003 553 560
5. I.D. Blainey, R.G. Adams, D.B. Brewer, and T.C. Harvey Cadmium-induced osteomalacia Br. J. Ind. Med. 37 1980 278 284
6. K. Kajikawa, I. Nakanishi, and K. Kuroda Morphological changes of the kidney and bone of rats in chronic cadmium poisoning Exp. Mol. Pathol. 34 1981 9 24
7. T. Kjellström Effects on bone, on vitamin D and calcium metabolism L. Friberg C.G. Elinder T. Kjellström G.F. Nordberg Cadmium and health: a toxicological and epidemiological appraisal 1986 CRC Press Boca Raton, FL 111 158
8. H. Ohta, Y. Yamauchi, M. Nakakita, H. Tanaka, S. Asami, and Y. Seki Relationship between renal dysfunction and bone metabolism disorder in male rats after long-term oral quantitative cadmium administration Ind. Health 38 2000 339 355
9. K. Uriu, I. Morimoto, K. Kai, Y. Okazaki, Y. Okada, and Y.L. Qie Uncoupling between bone formation and resorption in ovariectomized rats with chronic cadmium exposure Toxicol. Appl. Pharmacol. 164 2000 264 272
10. T. Alfvén, C.G. Elinder, M.D. Carlsson, A. Grubb, L. Hellström, and B. Persson Low-level cadmium exposure and osteoporosis J. Bone Miner. Res. 15 2000 1579 1586
11. R. Honda, I. Tsuritani, Y. Noborisaka, H. Suzuki, and M. Ishizaki Urinary cadmium excretion is correlated with calcaneal bone mass in Japanese women living in an urban area Environ. Res. 91 2003 63 70
12. L. Järup, T. Alfvén, B. Persson, G. Toss, and C.G. Elinder Cadmium may be a risk factor for osteoporosis Occup. Environ. Med. 55 1998 435 439
13. J.A. Staessen, H.A. Roels, D. Emelianov, T. Kuznetsova, L. Thijs, and J. Vangronsveld Environmental exposure to cadmium, forearm bone density, and risk of fractures: prospective population study Lancet 353 1999 1140 1144
14. Y. Dohi, K. Sugimoto, T. Yoshikawa, H. Ohgushi, T. Katsuda, and S. Tabata Effect of cadmium on osteogenesis within diffusion chambers by bone marrow cells: biochemical evidence of decreased bone formation capacity Toxicol. Appl. Pharmacol. 120 1993 274 280
15. K. Iwami, and T. Moriyama Comparative effect of cadmium on osteoblastic cells and osteoclastic cells Arch. Toxicol. 67 1993 352 357
16. M.M. Brzóska, J. Rogalska, and J. Moniuszko-Jakoniuk The concentration of vitamin D metabolites in the serum of cadmium-exposed female rats Osteoporosis Int. 14 Suppl 6 2003 22 23 (abstract)
17. M.M. Brzóska, K. Majewska, and J. Moniuszko-Jakoniuk Mineral status and mechanical properties of lumbar spine of female rats chronically exposed to various levels of cadmium Bone 34 2004 517 526
18. M.M. Brzóska, and J. Moniuszko-Jakoniuk Disorders in bone metabolism of female rats chronically exposed to cadmium Toxicol. Appl. Pharmacol. 2004 (in press)
19. S. Satarug, J.R. Baker, S. Urbenjapol, M. Haswell-Elkins, P.E. Reilly, and D.J. Williams A global perspective on cadmium pollution and toxicity in non-occupationally exposed population Toxicol. Lett. 137 2003 65 83
20. A.R. Giles Guidelines for the use of animals in biomedical research Thromb. Haemostasis 58 1987 1078 1084
21. R. Swaminathan Biochemical markers of bone turnover Clin. Chim. Acta 313 2001 95 105
22. WHO Study Group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Technical Report 843. World Health Organization, Geneva 1994.
23. G.L. Peterson A simplification of the protein assay method of Lowry et al, which is more generally applicable Anal. Biochem. 83 1977 346 356
24. D. Schapira, S. Linn, M. Sarid, S. Mokadi, A. Kabala, and M. Silbermann Calcium and vitamin D enriched diets increase and preserve vertebral mineral content in aging laboratory rats Bone 16 1995 575 582
25. J.A. Kanis Calcium nutrition and its implications for osteoporosis. Part II. After menopause Eur. J. Clin. Nutr. 48 1994 833 841
26. M.P. Akhter, U.T. Iwaniec, G.R. Haynatzki, Y.K. Fung, D.M. Cullen, and R.R. Recker Effects of nicotine on bone mass and strength in aged female rats J. Orthop. Res. 21 2003 14 19
27. C. García-Moreno, O.M. Calvo, S. Herrero, E. Martín, B. Suquía, and J.I. san Román Heterogenous decrease of bone mineral density in the vertebral column of ovariectomized rats Bone 16 1995 295S 300S (Suppl)
28. H.W. Sampson Alcohol and other factors affecting osteoporosis risk in women Alcohol Res. Health 26 2002 292 298
29. I.M. Olsson, I. Bensryd, T. Lundh, H. Ottosson, S. Skarfving, and A. Oskarsson Cadmium in blood and urine-impact of sex, age, dietary intake, iron status, and former smoking-association of renal effects Environ. Health Perspect. 110 2002 1185 1190
30. G.J. Long The effect of cadmium on cytosolic free calcium, protein kinase C, and collagen synthesis in rat osteosarcoma (ROS 17/2.8) cells Toxicol. Appl. Pharmacol. 143 1997 189 195
31. T. Miyahara, H. Yamada, M. Takeuchi, T. Kato, and H. Sudo Inhibitory effects of cadmium on in vitro calcification of a clonal osteogenic cell, MC3T3-E1 Toxicol. Appl. Pharmacol. 96 1988 52 59
32. J.A. Kanis Calcium nutrition and its implications for osteoporosis. I. Part, Children and healthy adults Eur. J. Clin. Nutr. 48 1994 757 767
33. R. Shapiro, and R.P. Heaney Co-dependence of calcium and phosphorus for growth and bone development under conditions of varying deficiency Bone 32 2003 532 540
34. S.L. Morgan Calcium and vitamin D in osteoporosis Osteoporosis 27 2001 101 130
35. 109Cd accumulation in the calcified parts of rat bones Toxicology 159 2001 1 10
36. K. Ogoshi, T. Moriyama, and Y. Nanzai Decrease in the mechanical strength of bones of rats administered cadmium Arch. Toxicol. 63 1989 320 324
37. B.J. Riss The role of bone turnover in the pathophysiology of osteoporosis Br. J. Obstet. Gynaecol. 103 Suppl 13 1996 9 15
38. I. Tsuritani, R. Honda, M. Ishizaki, Y. Yamada, K. Aoshima, and M. Kasuya Serum bone-type alkaline phosphatase activity in women living in a cadmium-polluted area Toxicol. Lett. 71 1994 209 216
39. M.M. Brzóska, M. Kamiński, D. Supernak-Bobko, K. Zwierz, and J. Moniuszko-Jakoniuk Changes in the structure and function of the kidney of rats chronically exposed to cadmium. I. Biochemical and histopathological studies Arch. Toxicol. 77 2003 344 352
40. M.M. Brzóska, M. Kamiński, W. Dziki, and J. Moniuszko-Jakoniuk Changes in the structure and function of the kidney of rats chronically exposed to cadmium. II. Histoenzymatic studies Arch. Toxicol. 78 2004 226 231
41. B. Piłat-Marcinkiewicz, B. Sawicki, M.M. Brzóska, and M. Zabel Preliminary immunohistochemical study of C cells of the thyroid and endocrine cells of the parathyroid glands in rats after prolonged exposure to cadmium Folia Histochem. Cytobiol. 39 2001 191 192
42. B. Piłat-Marcinkiewicz, B. Sawicki, M.M. Brzóska, and J. Moniuszko-Jakoniuk Effect of chronic administration of cadmium on the rat thyroid: radioimmunological and immunohistochemical studies Folia Histochem. Cytobiol. 40 2002 95 96
43. H. Ohta, M. Ichikawa, and Y. Seki Effects of cadmium intake on bone metabolism of mothers during pregnancy and lactation Tohoku J. Exp. Med. 96 2002 33 42
44. M.H. Bhattacharyya, N.A. Sacco-Gibson, and D.P. Peterson Cadmium-induced bone loss: increased susceptibility in female beagles after ovariectomy IARC Sci. Publ. 118 1992 279 286
45. 45Ca in non-pregnant mice on a calcium-deficient diet: evidence of direct effect of cadmium on bone Toxicol. Appl. Pharmacol. 120 1993 228 239
46. A.K. Wilson, and M.H. Bhattacharyya Effects of cadmium on bone: an in vivo model for the early response Toxicol. Appl. Pharmacol. 145 1997 68 73
47. N. Sacco-Gibson, S. Chaudhry, A. Brock, A.B. Sickles, B. Palet, and R. Hegstad Cadmium effects on bone metabolism: accelerated resorption in ovariectomized, aged beagles Toxicol. Appl. Pharmacol. 113 1992 274 283
48. J.H. Choi, I.K. Rhee, K.Y. Park, K.Y. Park, J.K. Kim, and S.J. Rhee Action of green tea catechin on bone metabolic disorders in chronic cadmium-poisoned rats Life Sci. 73 2003 1479 1489