Uncoupling between bone formation and resorption in ovariectomized rats with chronic cadmium exposure

Toxicology and Applied Pharmacology

Volumn 164, Issue 3, 2000, Pages 264-272

  Uriu, Kohei ^a   Morimoto, Isao ^a   Kai, Keiko ^a   Okazaki, Yuichi ^a   Okada, Yusuke ^a   Qie, Yue Ling ^a   Okimoto, Nobukazu ^a   Kaizu, Kazo ^a   Nakamura, Toshitaka ^a   Eto, Sumiya ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; DEOXYPYRIDINOLINE; OSTEOCALCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE DISEASE; BONE MINERAL; BONE STRENGTH; BONE STRUCTURE; CADMIUM POISONING; CONTROLLED STUDY; FEMALE; LONG TERM EXPOSURE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OVARIECTOMY; PATHOGENESIS; RAT; TOXICOKINETICS;

ANIMALIA;

EID: 0034193644     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2000.8908     Document Type: Article

References (47)

1. 3 in rats. Toxicol. Appl. Pharmacol. 89:1987;158-164.
2. Bernard A., Lauwerys R., Gengoux P. Characterization of the proteinuria induced by prolonged oral administration of cadmium in female rats. Toxicology. 20:1981;345-357.
3. Bhattacharyya M. H., Whelton B. D., Stern P. H., Peterson D. P. Cadmium accelerates bone loss in ovariectomized mice and fetal rat limb bones in culture. Proc. Natl. Acad. Sci. USA. 85:1988;8761-8765.
4. Bikle D. D. Bone disease due to nutritional, gastrointestinal, and hepatic disorders. Coe F. L., Favus M. J. Disorders of Bone and Mineral Metabolism. 1992;951-976 Raven Press, New York.
5. Blainey J. D., Adams R. G., Brewer D. B., Harvey T. C. Cadmium-induced osteomalacia. Br. J. Ind. Med. 37:1980;278-284.
6. Blumenthal N. C., Cosma V., Skyler D., LeGeros J., Walters M. The effect of cadmium on the formation and properties of hydroxyapatite in vitro and its relation to cadmium toxicity in the skeletal system. Calcif. Tissue Int. 56:1995;316-322.
7. Christoffersen J., Christoffersen M. R., Larsen R., Rostrup E., Tingsgaard P., Andersen O., Grandjean P. Interaction of cadmium ions with calcium hydroxyapatite crystals: A possible mechanism contributing to the pathogenesis of cadmium-induced bone diseases. Calcif. Tissue Int. 42:1988;331-339.
8. Dalton R. E., Wiseman M. J., Turner C., Viberti G. Measurement of urinary para-aminohippuric acid in glycosuric diabetics. Kidney Int. 34:1988;117-120.
9. Dempster D. W., Cosman F., Parisien M., Shen V., Lindsay R. Anabolic actions of parathyroid hormone on bone. Endocr. Rev. 14:1993;690-709.
10. Dohi Y., Sugimoto K., Yoshikawa T., Ohgushi H., Katsuda T., Tabata S., Moriyama T. Effect of cadmium on osteogenesis within diffusion chambers by bone marrow cells: Biochemical evidence of decreased bone formation capacity. Toxicol. Appl. Pharmacol. 120:1993;274-280.
11. Felson D. T., Zhang Y., Hannan M. T., Anderson J. J. Effects of weight and body mass index on bone mineral density in men and women: The Framingham Study. J. Bone Miner. Res. 8:1993;567-573.
12. Friberg L., Elinder C. G., Kjellstrom T., Nordberg G. F. Cadmium and Health: A Toxicological and Epidemiological Appraisal. 1985;CRC Press, Boca Raton.
13. Goulding A., Taylor R. W. Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in postmenopausal women. Calcif. Tissue Int. 63:1998;456-458.
14. Hiratsuka H., Katsuta O., Toyota N., Tsuchitani M., Akiba T., Marumo F., Umemura T. Iron deposition at mineralization fronts and osteoid formation following chronic cadmium exposure in ovariectomized rats. Toxicol. Appl. Pharmacol. 143:1997;348-356.
15. Hosoda K., Eguchi H., Nakamoto T., Kubota T., Honda H., Jindai S., Hasegawa R., Kiyoki M., Yamaji T., Shiraki M. Sandwich immunoassay for intact human osteocalcin. Clin. Chem. 38:1992;2233-2238.
16. Hyldstrup L., Andersen T., McNair P., Breum L., Transbol I. Bone metabolism in obesity: Changes related to severe overweight and dietary weight reduction. Acta Endocrinol. 129:1993;393-398.
17. Itokawa Y., Abe T., Tabei R., Tanaka S. Renal and skeletal lesions in experimental cadmium poisoning. Arch. Environ. Health. 28:1974;149-154.
18. Jarup L., Alfven T., Persson B., Toss G., Elinder C. G. Cadmium may be a risk factor for osteoporosis. Occup. Environ. Med. 55:1998a;435-439.
19. Jarup L., Berglund M., Elinder C. G., Norberg G., Vahter M. Health effects of cadmium exposure - a review of the literature and a risk estimate. Scand. J. Work Environ. Health. 24:1998b;7-51.
20. Kajikawa K., Nakanishi I., Kuroda K. Morphological changes of the kidney and bone of rats in chronic cadmium poisoning. Exp. Mol. Pathol. 34:1981;9-24.
21. Katsuta O., Hiratsuka H., Matsumoto J., Iwata H., Toyama N., Tsuchitani M., Umemura T., Marumo F. Cadmium-induced osteomalatic and osteopetrotic lesions in ovariectomized rats. Toxicol. Appl. Pharmacol. 126:1994;58-68.
22. Kido T., Nogawa K., Yamada Y., Honda R., Tsuritani I., Ishizaki M., Yamaya H. Osteopenia in inhabitants with renal dysfunction induced by exposure to environmental cadmium. Int. Arch. Occup. Environ. Health. 61:1989;271-276.
23. Kjellstrom T. Mechanism and epidemiology of bone effects of cadmium. Nordberg G. F., Herber R. F. M., Alessio L. Cadmium in the Human Environment: Toxicity and Carcinogenicity. 1992;301-310 International Agency for Research on Cancer (IARC), Lyon.
24. Li J. P., Akiba T., Marumo F. Long-term, low-dose, cadmium-induced nephropathy with renal osteopathy in ovariectomized rats. J. Toxicol. Sci. 22:1997;185-198.
25. Lorentzon T., Larsson S. E. Vitamin D metabolism in adult rats at low and normal calcium intake and the effect of cadmium exposure. Clin. Sci. Mol. Med. 30:1977;559-562.
26. Malluche H., Faugere M.-C. Renal bone disease 1990: An unmet challenge for nephrologist. Kidney Int. 38:1990;193-211.
27. Miyahara T., Yamada H., Takeuchi M., Kozuka H., Kato T., Sudo H. Inhibitory effects of cadmium on in vitro calcification of a clonal osteogenic cell, MC3T3-E1. Toxicol. Appl. Pharmacol. 96:1988;52-59.
28. Miyahara T., Takata M., Miyata M., Nagai M., Sugure A., Kozuka H., Kuzu S. Cadmium stimulates osteoclast-like multinucleated cell formation in mouse bone marrow cell cultures. Bull. Environ. Contam. Toxicol. 47:1991;283-287.
29. Mosekilde L., Danielsen C. C., Knudsen U. B. The effects of aging and ovariectomy on the vertebral bone mass and biomechanical properties of mature rats. Bone. 14:1993;1-6.
30. Motoie H., Nakamura T., O'uchi N., Nishikawa H., Kanoh H., Abe H., Kawashima H. Effects of YM175 on bone mineral density, strength, structure, and turnover in ovariectomized beagles on concomitant dietary calcium restriction. J. Bone Miner. Res. 10:1995;910-920.
31. Murakami H., Nakamura T., Tsurukami H., Abe M., Barbier A., Suzuki K. Effects of tiludronate on bone mass, structure, and turnover at the epiphyseal, primary, and secondary spongiosa in the proximal tibia of growing rats after sciatic neurectomy. J. Bone Miner. Res. 9:1994;1355-1364.
32. Noda M., Kitagawa M. A quantitative study of iliac bone histopathology on 62 cases with Itai-Itai disease. Calcif. Tissue Int. 47:1990;66-74.
33. Nogawa K., Tsuritani I., Kido T., Honda R., Ishizaki M., Yamada Y. Serum vitamin D metabolites in cadmium-exposed persons with renal damage. Int. Arch. Occup. Environ. Health. 62:1990;189-193.
34. Ogoshi K., Moriyama T., Nanzai Y. Decrease in the mechanical strength of bones of rats administered cadmium. Arch. Toxicol. 63:1989;320-324.
35. Ogoshi K., Nanzai Y., Moriyama T. Decrease in bone strength of cadmium-treated young and old rats. Arch. Toxicol. 66:1992;315-320.
36. Okimoto N., Tsurukami H., Okazaki Y., Nishida S., Sakai A., Ohnishi H., Hori M., Yasukawa K., Nakamura T. Effects of a weekly injection of human parathyroid hormone (1-34) and withdrawal on bone mass, strength, and turnover in mature ovariectomized rats. Bone. 22:1998;523-531.
37. Parfitt A. M., Podenphant J., Villanueva A. R., Frame B. Metabolic bone disease with and without osteomalacia after intestinal bypass surgery: A bone histomorphometric study. Bone. 6:1985;211-220.
38. Tsunenari T., Fukase M., Fujita T. Bone histomorphometric analysis for the cause of osteopenia in vitamin C-deficient rat (ODS rat). Calcif. Tissue Int. 48:1991;18-27.
39. 3 (ED-71), increases bone mass by stimulating the bone formation in normal and ovariectomized rats. Calcif. Tissue Int. 54:1994;142-149.
40. Uriu K., Kaizu K., Komine N., Ikeda M., Qie Y. L., Hashimoto O., Matsuoka A., Eto S. Renal hemodynamics in rats with cadmium-induced nephropathy. Toxicol. Appl. Pharmacol. 150:1998;76-85.
41. Wang C., Bhattacharyya M. H. Effect of cadmium on bone calcium and 45Ca in non-pregnant mice on a calcium-deficient diet: Evidence of direct effect of cadmium on bone. Toxicol. Appl. Pharmacol. 120:1993;228-239.
42. Waugh W. H. Photometry of inulin and polyfructosan by use of a cysteine/tryptophan reaction. Clin. Chem. 23:1977;639-645.
43. Wilson A. K., Cerny E. A., Smith B. D., Wagh A., Bhattacharyya M. H. Effects of cadmium on osteoclast formation and activity in vitro. Toxicol. Appl. Pharmacol. 140:1996;451-460.
44. Wilson A. K., Bhattarchayya M. H. Effects of cadmium on bone: An in vivo model for early response. Toxicol. Appl. Pharmacol. 145:1997;68-73.
45. Yamashita H., Kitagawa M. Histomorphometric study of ribs with Looser zones in Itai-Itai disease. Calcif. Tissue Int. 58:1996;170-176.
46. Yamaura M., Nakamura T., Tsurukami H., Hijioka A., Narusawa K., Ohnishi H., Ohta K., Hosoda K. Local bone turnover in the metaphysis of the proximal tibia and the lumbar vertebra during the early periods after ovariectomy in rats. Calcif. Tissue Int. 58:1996;52-59.
47. Yoshiki S., Yanagisawa T., Kimura M., Otaki N., Suzuki M., Suda T. Bone and kidney lesions in experimental cadmium intoxication. Arch. Environ. Health. 30:1975;559-562.