In vitro and in vivo activity of frenolicin B against Plasmodium falciparum and P berghei

Journal of Antibiotics

Volumn 64, Issue 12, 2011, Pages 799-801

  Fitzgerald, Jay T ^a   Henrich, Philipp P ^a   O'Brien, Connor ^b   Krause, Michael ^c   Ekland, Eric H ^b   Mattheis, Corinna ^b   Sá, Juliana M ^c   Fidock, David ^b   Khosla, Chaitan ^a,d  

^a STANFORD UNIVERSITY   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d Stanford University   (United States)

Author keywords

frenolicin; malaria; plasmodium9; polyketide

Indexed keywords

AMODIAQUINE; ANTIMALARIAL AGENT; CHLOROQUINE; DEOXYFRENOLICIN; FRENOLICIN A; FRENOLICIN B; PIPERAQUINE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; DRUG BIOAVAILABILITY; DRUG INHIBITION; DRUG ISOLATION; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA, FALCIPARUM; MICE; NAPHTHOQUINONES; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 84255195154     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.94     Document Type: Article

References (13)

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