Nestin + cells and healing the infarcted heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 1, 2012, Pages

  Calderone, Angelino ^a  

^a MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Cardiac regeneration; Ischemia; Myofibroblasts; Stem cells

Indexed keywords

SMOOTH MUSCLE ACTIN;

CELL CULTURE; CELL ISOLATION; CELL POPULATION; CELL TYPE; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE FIBROSIS; HEART TRANSPLANTATION; HUMAN; MYOFIBROBLAST; NESTIN CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVASCULARIZATION; REVIEW; STEM CELL; TISSUE REGENERATION; WOUND HEALING;

ANIMALS; COLLAGEN; FIBROSIS; HUMANS; INTERMEDIATE FILAMENT PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOFIBROBLASTS; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE REGENERATION; NERVE TISSUE PROTEINS; RECOVERY OF FUNCTION; STEM CELLS; WOUND HEALING;

EID: 84255167185     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00716.2011     Document Type: Review

References (68)

1. Aihara M, Sugawara K, Torii S, Hosaka M, Kurihara H, Saito N, Takeuchi T. Angiogenic endothelium-specific nestin expression is enhanced by the first intron of the nestin gene. Lab Invest 84: 1581-1592, 2004.
2. Amoh Y, Li L, Yang M, Moossa AR, Katsuoka K, Penman S, Hoffman RM. Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells. Proc Natl Acad Sci USA 101: 13291-13295, 2004.
3. Barandon L, Couffinhal T, Ezan J, Dufourcq P, Costet P, Alzieu P, Leroux L, Moreau C, Dare D, Duplaa C. Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA. Circulation 108: 2282-2289, 2003.
4. Béguin P, Gosselin H, Mamarbachi M, Calderone A. Nestin expression is lost in ventricular fibroblasts during postnatal development of the rat heart and re-expressed in scar myofibroblasts. J Cell Physiol. 2011 Apr 18. doi:10.1002/jcp.22794. [Epub ahead of print].
5. + cardiac myocyte-like cells following infarction. J Appl Physiol 107: 1241-1248, 2009.
6. (+) stem cells independently contribute to neural remodelling of the ischemic heart. J Cell Physiol 226: 1157-1165, 2011.
7. Bellafiore M, Sivverini G, Cappello F, Palma DA, Farina F, Zummo G. Research of cardiomyocyte precursors in adult rat heart. Tissue Cell 38: 345-351, 2006.
8. Birbrair A, Wang ZM, Messi ML, Enikolopov GN, Delbono O. Nestin-GFP transgene reveals neural precursor cells in adult skeletal muscle (Abstract). PLoS One 6: e16816, 2011.
9. Calderone A, Bel-Hadj S, Drapeau J, El-Helou V, Gosselin H, Clement R Villeneuve L. Scar myofibroblasts of the infarcted rat heart express natriuretic peptides. J Cell Physiol 207: 165-173, 2006.
10. Callegari A, Bollini S, Iop L, Chiavegato A, Torregrossa G, Pozzobon Gerosa G M, De Coppi P, Elvassore N, Sartore S. Neovascularization induced by porous collagen scaffold implanted on intact and cryoinjured rat hearts. Biomaterials 28: 5449-5461, 2007.
11. Cao JM, Chen LS, KenKnight BH, Ohara T, Lee MH, Tsai J, Lai WW, Karagueuzian HS, Wolf PL, Fishbein MC, Chen PS. Nerve sprouting and sudden cardiac death. Circ Res 86: 816-821, 2000.
12. Carlsson L, Li Z, Paulin D, Thornell LE. Nestin is expressed during development and in myotendinous and neuromuscular junctions in wild type and desmin knock-out mice. Exp Cell Res 251: 213-223, 1999.
13. Cimini M, Fazel S, Zhuo S, Xaymardan M, Fujii H, Weisel RD, Li RK. c-Kit dysfunction impairs myocardial healing after infarction. Circulation 116, Suppl 11: I77-I82, 2007.
14. Communal C, Colucci WS. The control of cardiomyocyte apoptosis via the beta-adrenergic signaling pathways. Arch Mal Coeur Vaiss 98: 236-241, 2005.
15. Crespel A, Rigau V, Coubes P, Rousset MC, de Bock F, Okano H, Baldy-Moulinier M, Bockaert J, Lerner-Natoli M. Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiol Dis 19: 436-450, 2005.
16. Dahlstrand J, Zimmerman LB, McKay RD, Lendahl U. Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments. J Cell Sci 103: 589-597, 1992.
17. Dai W, Wold LE, Dow JS, Kloner RA. Thickening of the infarcted wall by collagen injection improves left ventricular function in rats. J Am Coll Cardiol 46: 714-719, 2005.
18. Drapeau J, El-Helou V, Clement R, Bel-Hadj S, Gosselin H, Trudeau LE, Villeneuve L, Calderone A. Nestin-expressing neural stem cells identified in the scar following myocardial infarction. J Cell Physiol 204: 51-62, 2005.
19. Du XJ. Sympathoadrenergic mechanisms in functional regulation and development of cardiac hypertrophy and failure: findings from genetically engineered mice. Cardiovasc Res 50: 443-453, 2001.
20. El-Helou V, Béguin PC, Assimakopoulos J, Clement R, Gosselin H, Brugada R, Aumont A, Biernaskie J, Villeneuve L, Leung TK, Fer-nandes KJ, Calderone A. The rat heart contains a neural stem cell population; role in sympathetic sprouting and angiogenesis. J Mol Cell Cardiol 45: 694-702, 2008.
21. + neural-like stem cells and fibres were detected in the normal and damaged rat myocardium. Hypertension 46: 1219-1225, 2005.
22. El-Helou V, Proulx C, Assimakopoulos J, Béguin P, Gosselin H, Clement R, Villeneuve L, Huot-Marchand JÉ; Deblois D, Lajoie C, Calderone A. The cardiac neural stem cell phenotype is compromised in streptozotocin-induced diabetic cardiomyopathy. J Cell Physiol 220: 440-449, 2009.
23. + cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest 116: 1865-1877, 2006.
24. Fernandes KJ, McKenzie IA, Mill P, Smith KM, Akhavan M, Barnabé-Heider F, Biernaskie J, Junek A, Kobayashi NR Toma JG, Kaplan DR Labosky PA, Rafuse V, Hui CC, Miller FD. A dermal niche for skin-derived precursor cells. Nat Cell Biol 6: 1082-1093, 2004.
25. Frangogiannis NG, Smith CW, Entman ML. The inflammatory response in myocardial infarction. Cardiovasc Res 53: 31-47, 2002.
26. Galli R, Gritti A, Bonfanti L, Vescovi AL. Neural stem cells: an overview. Circ Res 92: 598-608, 2003.
27. Ha Y, Choi JU, Yoon DH, Cho YE, Kim TS. Nestin and small heat shock protein expression on reactive astrocytes and endothelial cells in cerebral abscess. Neurosci Res 44: 207-212, 2002.
28. Huang YL, Shi GY, Lee H, Jiang M, Huang BM, Wu HL, Yang HY. Thrombin induces nestin expression via the transactivation of EGFR signalling in rat vascular smooth muscle cells. Cell Signal 21: 954-968, 2009.
29. Ishiwata T, Matsuda Y, Naito Z. Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis. World J Gastroenterol 17: 409-418, 2011.
30. Kachinsky AM, Dominov JA, Miller JB. Intermediate filaments in cardiac myogenesis: nestin in the developing mouse heart. J Histochem Cytochem 43: 843-847, 1995.
31. Kang H, Tian L, Son YJ, Zuo Y, Procaccino D, Love F, Hayworth C, Trachtenberg J, Mikesh M, Sutton L, Ponomareva O, Mignone J, Enikolopov G, Rimer M, Thompson W. Regulation of the intermediate filament protein nestin at rodent neuromuscular junctions by innervation and activity. J Neurosci 27: 5948-5957, 2007.
32. Lendahl U, Zimmerman LB, McKay RD. CNS stem cells express a new class of intermediate filament protein. Cell 23: 585-595, 1990.
33. Liam PR, Matsuzaki K, Noma M, Jackson BM, Eperjesi TJ, Plappert TJ, St. John-Sutton MG, Gorman JH 3rd, Gorman RC. Dermal filler injection: a novel approach for limiting infarct expansion. Ann Thorac Surg 87: 148-155, 2009.
34. Lothian C, Prakash N, Lendahl U, Wahlström GM. Identification of both general and region-specific embryonic CNS enhancer elements in the nestin promoter. Exp Cell Res 248: 509-519, 1999.
35. Maderna E, Salmaggi A, Calatozzolo C, Limido L, Pollo B. Nestin, PDGFRfj, CXCL12 and VEGF in glioma patients. Cancer Biol Ther 6: 1018-1024, 2007.
36. Mann KM, Ray JL, Moon ES, Sass KM, Benson MR. Calcineurin initiates smooth muscle cell differentiation in neural crest stem cells. J Cell Biol 165: 483-491, 2004.
37. Micera A, Vigneti E, Pickholtz D, Reich R, Pappo O, Bonini S, Maquart FX, Aloe L, Levi-Schaffer F. Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair. Proc Natl Acad Sci USA 98: 6162-6167, 2001.
38. Mignone JL, Kukekov V, Chiang A, Steindler D, Enikolopov G. Neural stem and progenitor cells in nestin-GFP transgenic mice. J Comp Neurol 469: 311-324, 2004.
39. Mokry J, Cízková D, Filip S, Ehrmann J, Österreicher J, Kolár Z, English D. Nestin expression by newly formed human blood vessels. Stem Cells Dev 13: 658-664, 2004.
40. Mokry J, Pudil R, Ehrmann J, Cizkova D, Osterreicher J, Filip S, Kolar Z. Reexpression of nestin in the myocardium of postinfarcted patients. Virchows Arch 453: 33-41, 2008.
41. Morita H, Suzuki G, Mishima T, Chaudhry PA, Anagnostopoulos PV, Tanhehco EJ, Sharov VG, Goldstein S, Sabbah HN. Effects of long-term monotherapy with metoprolol CR/XL on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure. Cardiovasc Drugs Ther 16: 443-449, 2002.
42. Oikawa H, Hayashi K, Maesawa C, Masuda T, Sobue K. Expression profiles of nestin in vascular smooth muscle cells in vivo and in vitro. Exp Cell Res 316: 940-950, 2010.
43. Oishi K, Ogawa Y, Gamon S, Uchida MK. Contractile responses of smooth muscle cells differentiated from rat neural stem cells. J Physiol 540: 139-152, 2002.
44. Pilla JJ, Gorman JH, Gorman RC. Theoretic impact of infarct compliance on left ventricular function. Ann Thorac Surg 87: 803-810, 2009.
45. Quaini F, Urbanek K, Beltrami AP, Finato N, Beltrami CA, Nadal-Ginard B, Kajstura J, Leri A, Anversa P. Chimerism of the transplanted heart. N Engl J Med 346: 5-15, 2002.
46. Sakairi T, Hiromura K, Yamashita S, Takeuchi S, Tomioka M, Ideura H, Maeshima A, Kaneko Y, Kuroiwa T, Nangaku M, Takeuchi T, Nojima Y. Nestin expression in the kidney with an obstructed ureter. Kidney Int 72: 307-318, 2007.
47. Scobioala S, Klocke R, Kuhlmann M, Tian W, Hasib L, Milting H, Koenig S, Stelljes M, El-Banayosy A, Tenderich G, Michel G, Bre-ithardt G, Nikol S. Up-regulation of nestin in the infarcted myocardium potentially indicates differentiation of resident cardiac stem cells into various lineages including cardiomyocytes. FASEB J 22: 1021-1031, 2008.
48. Sejersen T, Lendahl U. Transient expression of the intermediate filament nestin during skeletal muscle development. J Cell Sci 106: 1291-1300, 1993.
49. Squires CE, Escobar GP, Payne JF, Leonardi RA, Goshorn DK, Sheats NJ, Mains IM, Mingoia JT, Flack EC, Lindsey ML. Altered fibroblast function following myocardial infarction. J Mol Cell Cardiol 39: 699-707, 2005.
50. Tamura Y, Matsumura K, Sano M, Tabata H, Kimura K, Ieda M, Arai T, Ohno Y, Kanazawa H, Yuasa S, Kaneda R, Makino S, Nakajima K, Okano H, Fukuda K. Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction. Arterioscler Thromb Vasc Biol 31: 582-589, 2011.
51. Toma JG, McKenzie IA, Bagli D, Miller FD. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol 3: 778-784, 2001.
52. Tomioka M, Hiromura K, Sakair IT, Takeuchi S, Maeshima A, Kaneko Y, Kuroiwa T, Takeuchi T, Nojima Y. Nestin is a novel marker for renal tubulointerstitial injury in immunoglobulin A nephropathy. Nephrology (Carlton) 15: 568-574, 2010.
53. Tomita Y, Matsumura K, Wakamatsu Y, Matsuzaki Y, Shibuya I, Kawaguchi H, Ieda M, Kanakubo S, Shimazaki T, Ogawa S, Osumi N, Okano H, Fukuda K. Cardiac neural stem cells contribute to the dormant multipotent stem cell in the mammalian heart. J Cell Biol 170: 1135-1146, 2005.
54. Vaittinen S, Lukka R, Sahlgren C, Hurme T, Rantanen J, Lendahl U, Eriksson JE, Kalimo H. The expression of intermediate filament protein nestin as related to vimentin and desmin in regenerating skeletal muscle. J Neuropathol Exp Neurol 60: 588-597, 2001.
55. Virag T, Murry CH. Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol 163: 2433-2440, 2003.
56. Vracko R, Thorning D, Frederickson RG. Fate of nerve fibers in necrotic, healing and healed rat myocardium. Lab Invest 63: 490-501, 1990.
57. Wang Y, Ahmad N, Wani MA, Ashraf M. Hepatocyte growth factor prevents ventricular remodelling and dysfunction in mice via Akt pathway and angiogenesis. J Mol Cell Cardiol 37: 1041-1052, 2004.
58. Wiese C, Rolletschek A, Kania G, Blyszczuk P, Tarasov KV, Tarasova Y, Wersto RP, Boheler KR, Wobus AM. Nestin expression-a property of multi-lineage progenitor cells? Cell Mol Life Sci 61: 2510-2522, 2004.
59. Wurmser AE, Nakashima K, Summers RG, Toni N, D'Amour KA, Lie DC, Gage FH. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature 430: 350-356, 2004.
60. Xue XJ, Yuan XJ. Nestin is essential for mitogen-stimulated proliferation of neural progenitor cells. Mol Cell Neurosci 45: 26-36, 2010.
61. Yang J, Cheng L, Yan Y, Bian W, Tomooka Y, Shiurba R, Jing N. Mouse nestin cDNA cloning and protein expression in the cytoskeleton of transfected cells. Biochim Biophys Acta 1520: 251-254, 2001.
62. Yaworsky PJ, Kappen C. Heterogeneity of neural progenitor cells revealed by enhancers in the nestin gene. Dev Biol 205: 309-321, 1999.
63. Zaglia T, Dedja A, Candiotto C, Cozzi E, Schiaffino S, Ausoni S. Cardiac interstitial cells express GATA4 and control dedifferentiation and cell cycle re-entry of adult cardiomyocytes. J Mol Cell Cardiol 46: 653-662, 2009.
64. Zhang J, Ding L, Zhao Y, Sun W, Chen B, Lin H, Wang X, Zhang L, Xu B, Dai J. Collagen-targeting vascular endothelial growth factor improves cardiac performance after myocardial infarction. Circulation 119: 1776-1784, 2009.
65. Zhang LQ, Laato M. Innervation of normal and hypertrophic human scars and experimental wounds in the rat. Ann Chir Gynaecol 90, Suppl 215: 29-32, 2001.
66. Zhong H, Jin Z, Chen Y, Zhang T, Bian W, Cui X, Jing N. First intron of nestin gene regulates its expression during C2C12 myoblast differentiation. Acta Biochim Biophys Sin (Shanghai) 40: 526-532, 2008.
67. Zhou S, Chen LS, Miyauchi Y, Miyauchi M, Kar S, Kangavari S, Fishbein MC, Sharifi B, Chen PS. Mechanisms of cardiac nerve fiber sprouting after myocardial infarction in dogs. Circ Res 95: 76-83, 2004.
68. Zimmerman L, Parr B, Lenfahl U, Cunningham M, McKay R, Gavin B, Mann J, Vassileva G, McMahon A. Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron 12: 11-24, 1994.