Intraventricular hemorrhage in preterm infants: Coagulation perspectives

Seminars in Thrombosis and Hemostasis

Volumn 37, Issue 7, 2011, Pages 730-736

  Kuperman, Amir A ^a,b   Kenet, Gili ^c,d   Papadakis, Emmanuel ^e   Brenner, Benjamin ^b,f  

^a WESTERN GALILEE HOSPITAL   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

^e PAPAGEORGIOU GENERAL HOSPITAL   (Greece)

^f RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Intraventricular hemorrhage; prematurity; recombinant factor VIIa; thrombin; vitamin K

Indexed keywords

ALPHA 2 ANTIPLASMIN; ALPHA TOCOPHEROL; BLOOD CLOTTING FACTOR 9 COMPLEX; ETAMSYLATE; FRESH FROZEN PLASMA; IBUPROFEN; INDOMETACIN; PANCURONIUM; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTHROMBIN COMPLEX; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TISSUE PLASMINOGEN ACTIVATOR; VITAMIN K GROUP;

ANTICOAGULANT THERAPY; ARTERIAL CARBON DIOXIDE TENSION; BLOOD CLOTTING; BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; BRAIN VENTRICLE DILATATION; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; CRANIAL ULTRASOUND; DRUG DOSE REDUCTION; DRUG MECHANISM; DRUG MEGADOSE; DRUG SAFETY; ECHOGRAPHY; HEMATOCRIT; HEMOSTASIS; HUMAN; HYDROCEPHALUS; INFANT DISEASE; LOW BIRTH WEIGHT; NEUROIMAGING; NONHUMAN; PATHOGENESIS; PNEUMOTHORAX; PREMATURITY; PRIORITY JOURNAL; RISK FACTOR; SEIZURE; SUCTION; SYSTEMATIC REVIEW (TOPIC); VERY LOW BIRTH WEIGHT;

BLOOD COAGULATION FACTORS; CEREBRAL HEMORRHAGE; ETHAMSYLATE; FACTOR VIIA; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; PLASMA; VITAMIN K;

EID: 84255161637     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0031-1297163     Document Type: Conference Paper

References (65)

1. Fanaroff A A., Stoll B J., Wright L L. et al, NICHD Neonatal Research Network. Trends in neonatal morbidity and mortality for very low birthweight infants. Am J Obstet Gynecol 2007 196 2 147, e1-e8
2. Vohr B R., Garcia-Coll C, Mayfield S, Brann B, Shaul P, Oh W. Neurologic and developmental status related to the evolution of visual-motor abnormalities from birth to 2 years of age in preterm infants with intraventricular hemorrhage. J Pediatr 1989 115 2 296-302 (Pubitemid 19190358)
3. Volpe J J. Neurology of the Newborn. 3rd ed. Philadelphia Saunders 1995
4. Hambleton G, Wigglesworth J S. Origin of intraventricular haemorrhage in the preterm infant. Arch Dis Child 1976 51 9 651-659
5. Gould S J., Howard S. An immunohistochemical study of the germinal layer in the late gestation human fetal brain. Neuropathol Appl Neurobiol 1987 13 6 421-437 (Pubitemid 18068141)
6. Perlman J M., McMenamin J B., Volpe J J. Fluctuating cerebral blood-flow velocity in respiratory-distress syndrome. Relation to the development of intraventricular hemorrhage. N Engl J Med 1983 309 4 204-209 (Pubitemid 13070238)
7. Nakamura Y, Okudera T, Fukuda S, Hashimoto T. Germinal matrix hemorrhage of venous origin in preterm neonates. Hum Pathol 1990 21 10 1059-1062 (Pubitemid 20349230)
8. Reeder J D., Kaude J V., Setzer E S. Choroid plexus hemorrhage in premature neonates: recognition by sonography. AJNR Am J Neuroradiol 1982 3 6 619-622 (Pubitemid 13222008)
9. Papile L A., Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 1978 92 4 529-534 (Pubitemid 8293290)
10. Leviton A, Kuban K, Paneth N. Intraventricular haemorrhage grading scheme: time to abandon? Acta Paediatr 2007 96 9 1254-1256 (Pubitemid 47300682)
11. Vasileiadis G T. Grading intraventricular hemorrhage with no grades. Pediatrics 2004 113 4 930-931, author reply 930931
12. Hope P L., Gould S J., Howard S, Hamilton P A., Costello A M., Reynolds E O. Precision of ultrasound diagnosis of pathologically verified lesions in the brains of very preterm infants. Dev Med Child Neurol 1988 30 4 457-471
13. Amato M, Konrad D, Hppi P, Donati F. Impact of prematurity and intrauterine growth retardation on neonatal hemorrhagic and ischemic brain damage. Eur Neurol 1993 33 4 299-303 (Pubitemid 23210363)
14. Linder N, Haskin O, Levit O et al. Risk factors for intraventricular hemorrhage in very low birth weight premature infants: a retrospective case-control study. Pediatrics 2003 111 5 Pt 1 e590-e595
15. Lemons J A., Bauer C R., Oh W et al, NICHD Neonatal Research Network. Very low birth weight outcomes of the National Institute of Child health and human development neonatal research network, January 1995 through December 1996. Pediatrics 2001 107 1 E1
16. Horbar J D. Vermont-Oxford Network 1997 Database Summary. Burlington, VT Vermont-Oxford Network 1997
17. Levene M I., Fawer C L., Lamont R F. Risk factors in the development of intraventricular haemorrhage in the preterm neonate. Arch Dis Child 1982 57 6 410-417 (Pubitemid 12070735)
18. McCrea H J., Ment L R. The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate. Clin Perinatol 2008 35 4 777-792, vii
19. Whitelaw A. Intraventricular haemorrhage and posthaemorrhagic hydrocephalus: pathogenesis, prevention and future interventions. Semin Neonatol 2001 6 2 135-146 (Pubitemid 32705984)
20. Krishnamoorthy K S., Shannon D C., DeLong G R., Todres I D., Davis K R. Neurologic sequelae in the survivors of neonatal intraventricular hemorrhage. Pediatrics 1979 64 2 233-237 (Pubitemid 9218418)
21. Pinto-Martin J A., Whitaker A H., Feldman J F., Van Rossem R, Paneth N. Relation of cranial ultrasound abnormalities in low-birthweight infants to motor or cognitive performance at ages 2, 6, and 9 years. Dev Med Child Neurol 1999 41 12 826-833
22. Vohr B, Garcia Coll C, Flanagan P, Oh W. Effects of intraventricular hemorrhage and socioeconomic status on perceptual, cognitive, and neurologic status of low birth weight infants at 5 years of age. J Pediatr 1992 121 2 280-285
23. Vohr B R., Allan W C., Westerveld M et al. School-age outcomes of very low birth weight infants in the indomethacin intraventricular hemorrhage prevention trial. Pediatrics 2003 111 4 Pt 1 e340-e346
24. Ment L R., Bada H S., Barnes P D. et al. Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2002 58 12 1726-1738 (Pubitemid 34663570)
25. Andrew M, Paes B, Milner R et al. Development of the human coagulation system in the healthy premature infant. Blood 1988 72 5 1651-1657 (Pubitemid 18268649)
26. Andrew M, Paes B, Milner R et al. Development of the human coagulation system in the full-term infant. Blood 1987 70 1 165-172 (Pubitemid 17111257)
27. Reverdiau-Moalic P, Delahousse B, Body G, Bardos P, Leroy J, Gruel Y. Evolution of blood coagulation activators and inhibitors in the healthy human fetus. Blood 1996 88 3 900-906 (Pubitemid 26333312)
28. Salonvaara M, Riikonen P, Kekomäki R et al. Effects of gestational age and prenatal and perinatal events on the coagulation status in premature infants. Arch Dis Child Fetal Neonatal Ed 2003 88 4 F319-F323 (Pubitemid 36791635)
29. Cvirn G, Gallistl S, Leschnik B, Muntean W. Low tissue factor pathway inhibitor (TFPI) together with low antithrombin allows sufficient thrombin generation in neonates. J Thromb Haemost 2003 1 2 263-268
30. Cvirn G, Gallistl S, Kutschera J et al. Clot strength: a comparison between cord and adult blood by means of thrombelastometry. J Pediatr Hematol Oncol 2008 30 3 210-213 (Pubitemid 351496735)
31. Kisker C T., Perlman S, Bohlken D, Wicklund B. Measurement of prothrombin mRNA during gestation and early neonatal development. J Lab Clin Med 1988 112 4 407-412
32. Feusner J H., Slichter S J., Harker L A. Acquired haemostatic defects in the ill newborn. Br J Haematol 1983 53 1 73-84 (Pubitemid 13217077)
33. Schmidt B, Wais U, Pringsheim W, Kunzer W. Plasma elimination of antithrombin III is accelerated in term newborn infants. Eur J Pediatr 1984 141 225-227 (Pubitemid 14193907)
34. Corrigan J J. Jr, Sleeth J J., Jeter M, Lox C D. Newborn's fibrinolytic mechanism: components and plasmin generation. Am J Hematol 1989 32 4 273-278 (Pubitemid 20006487)
35. Gray O P., Ackerman A, Fraser A J. Intracranial haemorrhage and clotting defects in low-birth-weight infants. Lancet 1968 1 7542 545-548
36. Cade J F., Hirsh J, Martin M. Placental barrier to coagulation factors: its relevance to the coagulation defect at birth and to haemorrhage in the newborn. BMJ 1969 2 5652 281-283
37. Piotrowski A, Dabrowska-Wojciak I, Mikinka M et al. Coagulation abnormalities and severe intraventricular hemorrhage in extremely low birth weight infants. J Matern Fetal Neonatal Med 2010 23 7 601-606
38. Fowlie P W., Davis P G. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database Syst Rev 2002 3 CD000174
39. Fowlie P W., Davis P G., McGuire W. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database Syst Rev 2010 7 CD000174
40. Ment L R., Vohr B, Allan W et al. Outcome of children in the indomethacin intraventricular hemorrhage prevention trial. Pediatrics 2000 105 3 Pt 1 485-491 (Pubitemid 30129659)
41. Ojala R, Ikonen S, Tammela O. Perinatal indomethacin treatment and neonatal complications in preterm infants. Eur J Pediatr 2000 159 3 153-155 (Pubitemid 30139938)
42. Dani C, Bertini G, Pezzati M et al, IntraVentricular Ibuprofen Study Group. Prophylactic ibuprofen for the prevention of intraventricular hemorrhage among preterm infants: a multicenter, randomized study. Pediatrics 2005 115 6 1529-1535 (Pubitemid 43843160)
43. Van Overmeire B, Allegaert K, Casaer A et al. Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet 2004 364 9449 1945-1949 (Pubitemid 39574597)
44. Whitelaw A, Odd D. Postnatal phenobarbital for the prevention of intraventricular hemorrhage in preterm infants. Cochrane Database Syst Rev 2007 4 CD001691
45. Chiswick M L., Johnson M, Woodhall C et al. Protective effect of vitamin E (DL-alpha-tocopherol) against intraventricular haemorrhage in premature babies. Br Med J (Clin Res Ed) 1983 287 6385 81-84 (Pubitemid 13067408)
46. Phelps D L., Rosenbaum A L., Isenberg S J., Leake R D., Dorey F J. Tocopherol efficacy and safety for preventing retinopathy of prematurity: a randomized, controlled, double-masked trial. Pediatrics 1987 79 4 489-500 (Pubitemid 17051407)
47. Brion L P., Bell E F., Raghuveer T S. Vitamin E supplementation for prevention of morbidity and mortality in preterm infants. Cochrane Database Syst Rev 2003 4 CD003665
48. Cools F, Offringa M. Neuromuscular paralysis for newborn infants receiving mechanical ventilation. Cochrane Database Syst Rev 2000 4 CD002773
49. Hunt R, Hey E. Ethamsylate for the prevention of morbidity and mortality in preterm or very low birth weight infants. Cochrane Database Syst Rev 2010 1 CD004343
50. Hubbard D, Tobias J D. Intracerebral hemorrhage due to hemorrhagic disease of the newborn and failure to administer vitamin K at birth. South Med J 2006 99 11 1216-1220 (Pubitemid 44875845)
51. Andrew M. The relevance of developmental hemostasis to hemorrhagic disorders of newborns. Semin Perinatol 1997 21 1 70-85 (Pubitemid 27247329)
52. Hey E. Vitamin Kwhat, why, and when. Arch Dis Child Fetal Neonatal Ed 2003 88 2 F80-F83
53. Clarke P, Mitchell S. Vitamin K prophylaxis in preterm infants: current practices. J Thromb Haemost 2003 1 2 384-386
54. Costakos D T., Greer F R., Love L A., Dahlen L R., Suttie J W. Vitamin K prophylaxis for premature infants: 1 mg versus 0.5 mg. Am J Perinatol 2003 20 8 485-490 (Pubitemid 37493886)
55. Clarke P, Mitchell S J., Wynn R et al. Vitamin K prophylaxis for preterm infants: a randomized, controlled trial of 3 regimens. Pediatrics 2006 118 6 e1657-e1666 (Pubitemid 46397539)
56. American Academy of Pediatrics, Committee on Nutrition. Nutritional needs of preterm infants. In: Pediatric Nutrition Handbook. 5th ed. Elk Grove Village, IL American Academy of Pediatrics 2004 350-351
57. Crowther C A., Crosby D D., Henderson-Smart D J. Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage. Cochrane Database Syst Rev 2010 1 CD000229
58. Beverley D W., Pitts-Tucker T J., Congdon P J., Arthur R J., Tate G. Prevention of intraventricular haemorrhage by fresh frozen plasma. Arch Dis Child 1985 60 8 710-713 (Pubitemid 15226559)
59. Dani C, Poggi C, Ceciarini F, Bertini G, Pratesi S, Rubaltelli F F. Coagulopathy screening and early plasma treatment for the prevention of intraventricular hemorrhage in preterm infants. Transfusion 2009 49 12 2637-2644
60. Veldman A, Josef J, Fischer D, Volk W R. A prospective pilot study of prophylactic treatment of preterm neonates with recombinant activated factor VII during the first 72 hours of life. Pediatr Crit Care Med 2006 7 1 34-39
61. Waltl H, Födisch H J., Kurz R, Hohenauer L, Mitterstieler G, Rössler H. Intracranial haemorrhage in low-birth-weight infants and prophylactic administration of coagulation-factor concentrate. Lancet 1973 1 7815 1284-1286
62. Thomas D B., Burnard E D. Prevention of intravascular haemorrhage in low-birthweight babies. Lancet 1973 2 7828 562
63. Thomas D B., Burnard E D. Prevention of intraventricular haemorrhage in babies receiving artificial ventilation. Med J Aust 1973 1 19 933-936
64. Gupta J M., Starr H, Fincher P, Lam-Po-Tang P R. Intraventricular haemorrhage in the newborn. Med J Aust 1976 2 9 338-340
65. Turner T, Prowse C V., Prescott R J., Cash J D. A clinical trial on the early detection and correction of haemostatic defects in selected high-risk neonates. Br J Haematol 1981 47 1 65-75 (Pubitemid 11199769)