Low hemoglobin density potential marker of iron availability

International Journal of Laboratory Hematology

Volumn 34, Issue 1, 2012, Pages 47-51

  Urrechaga, E ^a   Unceta, M ^a   Borque, L ^b   Escanero, J F ^b  

^a HOSPITAL DE GALDAKAO   (Spain)

^b UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Erythrocytes; Functional iron deficiency; Hypochromic red blood cells; Low hemoglobin density

Indexed keywords

HEMOGLOBIN; IRON; TRANSFERRIN RECEPTOR;

ANEMIA; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; CHRONIC KIDNEY DISEASE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DENSITY; FEMALE; HUMAN; INFLAMMATION; IRON DEFICIENCY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RELIABILITY; SENSITIVITY AND SPECIFICITY;

ANEMIA; ANEMIA, IRON-DEFICIENCY; CHRONIC DISEASE; ERYTHROCYTE INDICES; FEMALE; HUMANS; INFLAMMATION; IRON; KIDNEY FAILURE, CHRONIC; MALE;

EID: 84155181111     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/j.1751-553X.2011.01355.x     Document Type: Article

References (22)

1. Arndt U., Kaltwasser J.P., Gottschalk R., Hoelzer D. & Möller B. (2005) Correction of iron-deficient erythropoiesis in the treatment of anemia of chronic disease with recombinant human. Annals of Haematology 84, 159-166.
2. Beguin Y. (2003) Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. Clinica Chimica Acta 329, 9-22.
3. Bovy C., Gothot A., Delanaye P., Warling X., Krzesinski J.M. & Beguin Y. (2007) Mature erythrocyte parameters as new markers of functional iron deficiency in hemodialysis. Nephrology Dialysis Transplantation 22, 1156-1162.
4. Brugnara C. (2002) A hematologic "gold standard" for iron deficient states? Clinical Chemistry 48, 981-982.
5. Brugnara C. (2003) Iron deficiency and erythropoiesis: new diagnostic approaches. Clinical Chemistry 49, 1573-1578.
6. Buttarello M., Pajola R., Novello E., Robeschini M., Cantaro S., Oliosi F., Naso A. & Plebani M. (2010) Diagnosis of iron deficiency diagnosis of iron deficiency in patients undergoing hemodialysis. American Journal of Clinical Pathology 133, 949-954.
7. Cavill I. & Mcdougall I.C. (1993) Functional iron deficiency. Blood, 82, 1137.
8. Cook J.D. (2005) Diagnosis and management of iron deficiency anemia. Best Practice and Research Clinical Hematology 18, 319-332.
9. Coyne D. (2006) Iron indices: what do they really mean? Kidney International 101, S4-S8.
10. Ioannou G.N., Spector J., Scott K. & Rockey D.C. (2002) Prospective evaluation of a clinical guideline for the diagnosis and management of iron deficiency anemia. American Journal of Medicine 113, 281-287.
11. Locateli F., Aljama P., Barany P., Canaud B., Carrera F., Eckardt K.U., Horl W.H., Macdougall I.C., Macleod A., Wiecek A. & Cameron S. (2004) European Best Practice Guidelines Working Group. Revised European best practice guidelines for the management of anaemia in patients with chronic renal failure. Nephrology Dialysis Transplantation 19(Suppl. 2), 1-47.
12. Marković M., Majkić-Singh N., Ignjatović S. & Singh S. (2007) Reticulocyte haemoglobin content vs. soluble transferrin receptor and ferritin index in iron deficiency anaemia accompanied with inflammation. International Journal of Laboratory Hematology 29, 341-346.
13. Mast A. (2001) The clinical utility of peripheral blood tests in the diagnosis of iron deficiency anemia. Bloodline 1, 7-9.
14. O'broin S., Kelleher B., Balfe A. & Mc Mahon C. (2005) Evaluation of serum transferrin receptor assay in a centralized iron screening service. Clinical and Laboratory Hematology 27, 190-194.
15. Punnonen K., Irjala K. & Rajamaki A. (1997) Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 89, 1052-1057.
16. Skikne B.S. (2008) Soluble transferrin receptor. American Journal of Hematology 83, 872-875.
17. Thomas C. & Thomas L. (2002) Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clinical Chemistry 48, 1066-1076.
18. Thomas L., Franck S., Messinger M., Linssen J., Thome M. & Thomas C. (2005) Reticulocyte hemoglobin measurement - comparison of two methods in the diagnosis of iron-restricted erythropoiesis. Clinical Chemistry and Laboratory Medicine 43, 1193-1202.
19. Urrechaga E. (2010) The new mature red cell parameter, low haemoglobin density of the Beckman-Coulter LH750: clinical utility in the diagnosis of iron deficiency. International Journal of Laboratory Hematology 32, e144-e150.
20. Urrechaga E., Borque L. & Escanero J.F. (2010) Erythrocyte and reticulocyte indices on the LH 750 as potential markers of functional iron deficiency. Anemia 2010, 1-7. Article ID 625919, doi:/625919
21. Weiss G. & Goodnough L.T. (2005) Anemia of chronic disease. New England Journal of Medicine 352, 1011-1023.
22. Wish J.B. (2006) Assessing iron status: beyond serum ferritin and transferrin saturation. Clinical Journal of the American Society of Nephrology 1, S4-S8.