Sclerosing epithelioid fibrosarcoma: Cytogenetic analysis of FUS rearrangement

Pathology International

Volumn 62, Issue 1, 2012, Pages 65-68

  Yoon, Nara ^a   Kwon, Jong Won ^a   Seo, Sung Wook ^a   Ahn, Geunghwan ^b   Choi, Yoon La ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Beta catenin; FUS; Sclerosing epithelioid fibrosarcoma

Indexed keywords

BETA CATENIN; CD34 ANTIGEN; DESMIN; MONOCLONAL ANTIBODY HMB 45; RNA BINDING PROTEIN; SMOOTH MUSCLE ACTIN;

ADULT; ARTICLE; CASE REPORT; CHROMOSOME REARRANGEMENT; CYTOGENETICS; EXON; FIBROSARCOMA; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HYALINE DEGENERATION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCLEROSING EPITHELIOID FIBROSARCOMA;

ADULT; BETA CATENIN; CYTOGENETIC ANALYSIS; FIBROSARCOMA; GENE FUSION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; RNA-BINDING PROTEIN FUS; SCLEROSIS; SOFT TISSUE NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; VIMENTIN;

EID: 84155180749     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2011.02752.x     Document Type: Article

References (15)

1. Ossendorf C, Studer GM, Bode B, Fuchs B. Sclerosing epithelioid fibrosarcoma: Case presentation and a systematic review. Clin Orthop Relat Res 2008; 466: 1485-91.
2. Wang G, Eyden B. A primary sclerosing epithelioid fibrosarcoma of the pubic bone, with evidence of divergent epithelial differentiation. Ultrastruct Pathol 2010; 34: 99-104.
3. Meis-Kindblom JM, Kindblom LG, Enzinger FM. Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma. Am J Surg Pathol 1995; 19: 979-93.
4. Antonescu CR, Rosenblum MK, Pereira P, Nascimento AG, Woodruff JM. Sclerosing epithelioid fibrosarcoma: A study of 16 cases and confirmation of a clinicopathologically distinct tumor. Am J Surg Pathol 2001; 25: 699-709.
5. Mertens F, Fletcher CD, Antonescu CR etal. Clinicopathologic and molecular genetic characterization of low-grade fibromyxoid sarcoma, and cloning of a novel FUS/CREB3L1 fusion gene. Lab Invest 2005; 85: 408-15.
6. Panagopoulos I, Storlazzi CT, Fletcher CD etal. The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma. Genes Chromosomes Cancer 2004; 40: 218-28.
7. Guillou L, Benhattar J, Gengler C etal. Translocation-positive low-grade fibromyxoid sarcoma: Clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: A study from the French Sarcoma Group. Am J Surg Pathol 2007; 31: 1387-402.
8. Rekhi B, Folpe AL, Deshmukh M, Jambhekar NA. Sclerosing epithelioid fibrosarcoma-a report of two cases with cytogenetic analysis of FUS gene rearrangement by FISH technique. Pathol Oncol Res 2011; 17: 145-8.
9. Smith PJ, Almeida B, Krajacevic J, Taylor B. Sclerosing epithelioid fibrosarcoma as a rare cause of ascites in a young man: A case report. J Med Case Reports 2008; 2: 248.
10. Kanno A, Hatori M, Hosaka M etal. Multiple bone metastasis of sclerosing epithelioid fibrosarcoma 12years after initial surgery-increasing ki-67 labeling index. Sarcoma 2009: 953750. Epub 2009 Mar 29
11. Vijayakumar S, Liu G, Rus IA etal. High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/beta-catenin target gene, CDC25A. Cancer Cell 2011; 19: 601-12.
12. Lazar AJ, Tuvin D, Hajibashi S etal. Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors. Am J Pathol 2008; 173: 1518-27.
13. Lips DJ, Barker N, Clevers H, Hennipman A. The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoid tumors). Eur J Surg Oncol 2009; 35: 3-10.
14. Salas S, Chibon F, Noguchi T etal. Molecular characterization by array comparative genomic hybridization and DNA sequencing of 194 desmoid tumors. Genes Chromosomes Cancer 2010; 49: 560-68.
15. Amini Nik S, Ebrahim RP, Van Dam K, Cassiman JJ, Tejpar S. TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations. Exp Cell Res 2007; 313: 2887-95.