A patient with anti-aquaporin 4 antibody presenting hypersomnolence as the initial symptom and symmetrical hypothalamic lesions

Journal of the Neurological Sciences

Volumn 312, Issue 1-2, 2012, Pages 18-20

  Deguchi, Kentaro ^a   Kono, Syoichiro ^a   Deguchi, Shoko ^a   Morimoto, Nobutoshi ^a   Ikeda, Masami ^a   Kurata, Tomoko ^a   Ikeda, Yoshio ^a   Matsuura, Tohru ^a   Kanbayashi, Takashi ^b   Takahashi, Toshiyuki ^c   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b AKITA UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aquaporin 4; Hypersomnolence; Neuromyelitis optica; Symmetrical hypothalamic lesions

Indexed keywords

AQUAPORIN 4 ANTIBODY; IMMUNOGLOBULIN G; METHYLPREDNISOLONE; OREXIN; PREDNISOLONE; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ADULT; AMNESIA; ANTIBODY BLOOD LEVEL; ARTICLE; BACKACHE; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; DAYTIME SOMNOLENCE; DISORIENTATION; ELECTROENCEPHALOGRAM; EVOKED VISUAL RESPONSE; FEMALE; HUMAN; HYPOTHALAMUS LESION; MINI MENTAL STATE EXAMINATION; MYELOOPTIC NEUROPATHY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NERVE LESION; PLEOCYTOSIS; PRIORITY JOURNAL; SHORT TERM MEMORY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOMNOLENCE; SPINAL CORD LESION; VISUAL SYSTEM EXAMINATION;

ADULT; AQUAPORIN 4; AUTOANTIBODIES; DIAGNOSIS, DIFFERENTIAL; DISORDERS OF EXCESSIVE SOMNOLENCE; FEMALE; HUMANS; HYPOTHALAMUS;

EID: 84155167263     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2011.08.031     Document Type: Article

References (17)

1. K. Tanaka, T. Tani, M. Tanaka, T. Saida, J. Idezuka, and M. Yamazaki Anti-aquaporin 4 antibody in selected Japanese multiple sclerosis patients with long spinal cord lesions Mult Scler 13 7 2007 850 855 (Pubitemid 351540855)
2. V.A. Lennon, T.J. Kryzer, S.J. Pittock, A.S. Verkman, and S.R. Hinson IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel J Exp Med 202 4 2005 473 477 (Pubitemid 41186945)
3. S. Nielsen, E.A. Nagelhus, M. Amiry-Moghaddam, C. Bourque, P. Agre, and O.P. Ottersen Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain J Neurosci 17 1 1997 171 180 (Pubitemid 27008860)
4. M. Amiry-Moghaddam, and O.P. Ottersen The molecular basis of water transport in the brain Nat Rev Neurosci 4 12 2003 991 1001 (Pubitemid 37486675)
5. S. Nishino, and T. Kanbayashi Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system Sleep Med Rev 9 4 2005 269 310 (Pubitemid 40982498)
6. H. Nozaki, T. Shimohata, T. Kanbayashi, Y. Sagawa, S. Katada, and M. Satoh A patient with anti-aquaporin 4 antibody who presented with recurrent hypersomnia, reduced orexin (hypocretin) level, and symmetrical hypothalamic lesions Sleep Med 10 2 2009 253 255
7. T. Kanbayashi, T. Shimohata, I. Nakashima, H. Yaguchi, I. Yabe, and M. Nishizawa Symptomatic narcolepsy in patients with neuromyelitis optica and multiple sclerosis: new neurochemical and immunological implications Arch Neurol 66 12 2009 1563 1566
8. T. Baba, I. Nakashima, T. Kanbayashi, M. Konno, T. Takahashi, and K. Fujihara Narcolepsy as an initial manifestation of neuromyelitis optica with anti-aquaporin-4 antibody J Neurol 256 2 2009 287 288
9. S.J. Pittock, B.G. Weinshenker, C.F. Lucchinetti, D.M. Wingerchuk, J.R. Corboy, and V.A. Lennon Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression Arch Neurol 63 7 2006 964 968 (Pubitemid 44036298)
10. I. Nakashima, K. Fujihara, I. Miyazawa, T. Misu, K. Narikawa, and M. Nakamura Clinical and MRI features of Japanese patients with multiple sclerosis positive for NMO-IgG J Neurol Neurosurg Psychiatry 77 9 2006 1073 1075 (Pubitemid 44338534)
11. T. Kanbayashi, Y. Sagawa, F. Takemura, S.U. Ito, K. Tsutsui, and Y. Hishikawa The pathophysiologic basis of secondary narcolepsy and hypersomnia Curr Neurol Neurosci Rep 11 2 2011 235 241
12. T. Kanbayashi, Y. Inoue, K. Kawanishi, H. Takasaki, R. Aizawa, and K. Takahashi CSF hypocretin measures in patients with obstructive sleep apnea J Sleep Res 12 4 2003 339 341 (Pubitemid 38010441)
13. T. Takahashi, K. Fujihara, I. Nakashima, T. Misu, I. Miyazawa, and M. Nakamura Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica Tohoku J Exp Med 210 4 2006 307 313 (Pubitemid 44883971)
14. D.M. Wingerchuk, V.A. Lennon, S.J. Pittock, C.F. Lucchinetti, and B.G. Weinshenker Revised diagnostic criteria for neuromyelitis optica Neurology 66 10 2006 1485 1489 (Pubitemid 43958540)
15. K. Yanai, and M. Tashiro The physiological and pathophysiological roles of neuronal histamine: an insight from human positron emission tomography studies Pharmacol Ther 113 1 2007 1 15 (Pubitemid 44969926)
16. A.Y. Poppe, Y. Lapierre, D. Melancon, D. Lowden, L. Wardell, and L.M. Fullerton Neuromyelitis optica with hypothalamic involvement Mult Scler 11 5 2005 617 621 (Pubitemid 41387709)
17. B. Carlander, T. Vincent, A. Le Floch, N. Pageot, W. Camu, and Y. Dauvilliers Hypocretinergic dysfunction in neuromyelitis optica with coma-like episodes J Neurol Neurosurg Psychiatry 79 3 2008 333 334 (Pubitemid 351303398)