Evaluation of cagA tyrosine phosphorylation DNA motifs in Helicobacter pylori isolates from gastric disorder patients in West of Iran

Scientific Research and Essays

Volumn 6, Issue 31, 2011, Pages 6454-6458

  Kargar, Mohammad ^a   Souod, Negar ^a   Ghorbani Dalini, Sadegh ^a   Doosti, Abbas ^b   Rezaeian, Abbas Ali ^a  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

CagA; Gastroduodenal diseases; Helicobacter pylori; Tyrosine phosphorylation motifs

Indexed keywords

EID: 84055211974     PISSN: None     EISSN: 19922248     Source Type: Journal    
DOI: 10.5897/SRE11.826     Document Type: Article

References (21)

1. Amador P, Delgado M, Ortiz M, Polanco M, Henao C (2009). Molecular and bioinformatic characterization of Helicobacter pylori CagA protein using gastric biopsies of Colombian patients. Rev. Col Gastroenterol., 24(4): 352-361
2. Bindayana KM, Baker WA, Botta GA (2006). Detection of Helicobacter pylori cagA gene in gastric biopsies, clinical isolates and faeces. Ind. J. med. microbiol., 24(3): 195-200
3. Dabiri H, Maleknejad P, Yamaoka Y, Feizabadi MM, Jafari F, Rezadehbashi M, Nakhjavani FA, Mirsalehian A, Zali MR (2009). Distribution of Helicobacter pylori cagA, cagE, oipA and vacA in different major ethnic groups in Tehran, Iran. J. Gastrol. hepatol., 24: 1380-1386
4. Gutierrez B, Vidal T, Valmana CE, Camou-Juncas C, Santos A, Megrud F, Gonzalez N, Leonard I, Martinez R, Diaz-Canel O (2005). Helicobacter pylori infection in Havana, Cuba. Prevalence and cagA status of the strains. Vacci Monitor., 14 (2): 15-19
5. Hussein NR, Mohammadi M, Talebkhan Y, Doraghi M, Letley DP, Muhammad MK, Argent RH, Atherton JC (2008). Differences in Virulence Markers between Helicobacter pylori Strains from Iraq and Those from Iran: Potential Importance of Regional Differences in H. pylori-Associated Disease. J. Clin. Microbiol., 46(5): 1774-1779
6. Jafari F, Shokrzadeh L, Dabiri H, Baghaei K, Yamaoka Y, Zojaji H, Haghazali M, Molaei M, Zali MR (2008). VacA genotypes of Helicobacter pylori in relation to cagA status and clinical outcomes in Iranian populations. Jpn. J. Infect Dis., 61: 290-293
7. Kargar M, Baghernejad M, Doosti A (2010). Role of NADPH-insensitive nitroreductase gene to metronidazole resistance of Helicobacter pylori strains. DARU, 18(2): 137-140
8. Kargar M, Baghernejad M, Doosti A, Ghorbani-Dalini S (2011a). Clarithromycin resistance and 23S rRNA mutations in Helicobacter pylori isolates in Iran. Afr J Microb Res., 5(8): 853-856
9. Kargar M, Ghorbani-Dalini S, Doosti A, Baghernejad M (2011b). Molecular assessment of clarithromycin resistant Helicobacter pylori strains using rapid and accurate PCR-RFLP method in gastric specimens in Iran. Afr. J. Biotech., 10(39): 7675-7678
10. Kargar M, Baghernejad M, Doosti A, Ghorbani-Dalini S (2011c). Clarithromycin resistance and 23S rRNA mutations in Helicobacter pylori. Oliviu Pasco (1st) Gasrtointestinal Endoscopy.InTech, Croatia, pp. 99-124
11. Kargar M, Ghorbani-Dalini S, Doosti A, Souod N (2011d). Real-time PCR for Helicobacter pylori quantification and detection of clarithromycin resistance in gastric tissues from patients with gastrointestinal disorders. Res Microbiol, DOI: 10.1016/j.resmic.2011.11.005.
12. Khayat AE, Soweid AM, Katter MM, Tawil AN, Elhaj II, Azar C, Gold BD, Matar GM (2007). Prevalence and clinical revelance of Helicobacter pylori cagA and vacA genes in Lebanese patients with gastritis and peptic ulcer diseases. J. Infect. developing countries., 1(1): 55-61
13. Monstein HJ, Karlsson A, Reberg A, Borch K (2010). Application of PCR amplicon sequencing using a single primer pair in PCR amplification to assess variations in Helicobacter pylori cagA EPIYA tyrosin phosphorilation motifs. BMC res notes, 3(35): 581-585
14. Nahaei M, Sharifi Y, Taghi Akhi M, Ashghaezade M, Nahayei M, Fatahi E (2008). Helicobacter pylori cagA and vacA genotypes and their relationship to peptic ulcer disease and non ulcer dysplasia. Rese. J. Microbiol., 3(5): 386-394
15. Occhialini A, Marais A, Urdaci M, Sierra R, Munoz N, Covacci A and Megraud F (2001). Composition and gene expression of the cag pathogenicity island in Helicobacter pylori strains isolated from gastric carcinoma and gastritis patients in Costa Rica. Infect. Immun., 69(3): 1902-1908
16. Odenbreit S, Gebert B, Puls J, Fischer W, Haas R (2001). Interaction of Helicobacter pylori with professional phagocytes: role of the cag pathogenicity island and translocation, phosphorylation and processing of CagA. Cell. Microbiol., 3(1): 21-31
17. Owen R, Sharp S, Chisholm, S, Rijpkema S (2003). Identification of cagA tyrosin phosphorilation DNA motifs in Helicobacter pylori isolates from PUD patients by novel PCR-Restriction fragment length polymorphism and real time fluorescence PCR assays. J. clin microbiol., 41(7): 3112-3118
18. Puls J, Fischer W, Haas R (2002). Activation of Helicobacter pylori CagA by tyrosine phosphorylation is essential for dephosphorylation of host cell proteins in gastric epithelial cells. Mol. Microbiol., 43(4): 961-969
19. Reyes A, Atherton J, Argent R, Puente JL, Torres J (2007). Heterogeneity in the activity of Mexican Helicobacter pylori strains on gastric epithelial cells and its association with diversity in the cagA gene. Am. Soc. microbial., 10. 1128: 1951-1956
20. Shokrzadeh L, Baghaei K, Yamaoka Y, Dabiri H, Jafari F, Sahebekhtiari N, Tahami A, Sugimoto M, Zojaji H, Zali MR (2010). Analysis of 3_end variable region of the cagA gene in Helicobacter pylori isolated from Iranian population. J. Gastrol. hepatol., 25: 172-177
21. Wang J, Chi DS, Laffan JJ, Li C, Ferguson DA Jr, Litchfield P and Thomas E (2002). Comparison of cytotoxin genotypes of Helicobacter pylori in stomach and saliva. Dig. Dis. Sci., 47: 1850-1856.