PERP gene therapy attenuates lung cancer xenograft via inducing apoptosis and suppressing VEGF

Cancer Biology and Therapy

Volumn 12, Issue 12, 2011, Pages 1114-1119

  Chen, Ke ^a,b,c   Luo, Zhaoyang ^c   Li, Zhongwu ^d   Liu, Yiqiang ^d   Zhao, Qingzheng ^b  

^a Chinese Academy of Sciences and China National Center for Bioinformation   (China)

^b CANCER HOSPITAL   (China)

^c UNIVERSITY OF SOUTH CHINA   (China)

^d PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Apoptosis; Caspase 3; Gene therapy; Lung cancer; PERP; Smac; TRAIL; VEGF

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; PERP PROTEIN; PROTEIN P53; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG CANCER; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; ENZYME ACTIVATION; FEMALE; GENES, TUMOR SUPPRESSOR; GENETIC THERAPY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIAL PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84055193566     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.12.12.18435     Document Type: Article

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