Treatment and screening of hypothyroidism in pregnancy: Results of a European survey

European Journal of Endocrinology

Volumn 166, Issue 1, 2012, Pages 49-54

  Vaidya, Bijay ^a   Hubalewska Dydejczyk, Alicja ^b   Laurberg, Peter ^c   Negro, Roberto ^d   Vermiglio, Francesco ^e   Poppe, Kris ^f  

^a ROYAL DEVON AND EXETER HOSPITAL   (United Kingdom)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

^d VITO FAZZI HOSPITAL   (Italy)

^e UNIVERSITY OF MESSINA   (Italy)

^f UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG DOSE INCREASE; ETHNIC GROUP; EUROPEAN; FEMALE; HEALTH CARE PLANNING; HEALTH SURVEY; HIGH RISK POPULATION; HORMONE SUBSTITUTION; HUMAN; HYPOTHYROIDISM; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; PATIENT MONITORING; PRACTICE GUIDELINE; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; QUESTIONNAIRE; RECOMMENDED DRUG DOSE; SCREENING TEST; THYROID FUNCTION TEST; TREATMENT RESPONSE;

ADULT; EUROPE; FEMALE; HUMANS; HYPOTHYROIDISM; PREGNANCY; PREGNANCY COMPLICATIONS; QUESTIONNAIRES; SOCIETIES, MEDICAL; THYROXINE; YOUNG ADULT;

EID: 84055184756     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-11-0729     Document Type: Article

References (25)

1. Krassas GE, Poppe K & Glinoer D. Thyroid function and human reproductive health. Endocrine Reviews 2010 31 702-755. (doi:10.1210/er.2009- 0041)
2. Glinoer D & Abalovich M. Unresolved questions in managing hypothyroidism during pregnancy. BMJ 2007 335 300-302. (doi:10.1136/bmj.39189. 513935.BE)
3. Burman KD. Controversies surrounding pregnancy, maternal thyroid status, and fetal outcome. Thyroid 2009 19 323-326. (doi:10.1089/thy.2009.1570)
4. Abalovich M, Amino N, Barbour LA, Cobin RH, De Groot LJ, Glinoer D, Mandel SJ & Stagnaro-Green A. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. Journal of Clinical Endocrinology and Metabolism 2007 92 S1-47. (doi:10.1210/jc.2007-0141)
5. Yassa L, Marqusee E, Fawcett R & Alexander EK. Thyroid hormone early adjustment in pregnancy (the THERAPY) trial. Journal of Clinical Endocrinology and Metabolism 2010 95 3234-3241. (doi:10.1210/jc.2010-0013)
6. Negro R, Schwartz A, Gismondi R, Tinelli A, Mangieri T & Stagnaro-Green A. Universal screening versus case finding for detection and treatment of thyroid hormonal dysfunction during pregnancy. Journal of Clinical Endocrinology and Metabolism 2010 95 1699-1707. (doi:10.1210/jc.2009-2009)
7. Stagnaro-Green A, Abalovich M, Alexander E, Azizi F, Mestman J, Negro R, Nixon A, Pearce EN, Soldin OP, Sullivan S & Wiersinga W. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 2011 21 1081-1125. (doi:10.1089/thy.2011.0087)
8. de Escobar GM, Obregon MJ & del Rey FE. Maternal thyroid hormones early in pregnancy and fetal brain development. Best Practice & Research. Clinical Endocrinology & Metabolism 2004 18 225-248. (doi:10.1016/j.beem. 2004.03.012)
9. Liu H, Momotani N, Noh JY, Ishikawa N, Takebe K & Ito K. Maternal hypothyroidism during early pregnancy and intellectual development of the progeny. Archives of Internal Medicine 1994 154 785-787. (doi:10.1001/archinte. 154.7.785)
10. Alexander EK, Marqusee E, Lawrence J, Jarolim P, Fischer GA & Larsen PR. Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. New England Journal of Medicine 2004 351 241-249. (doi:10.1056/NEJMoa040079)
11. Vaidya B, Anthony S, Bilous M, Shields B, Drury J, Hutchison S & Bilous R. Detection of thyroid dysfunction in early pregnancy: universal screening or targeted high-risk case finding? Journal of Clinical Endocrinology and Metabolism 2007 92 203-207. (doi:10.1210/jc.2006-1748)
12. Rotondi M, Mazziotti G, Sorvillo F, Piscopo M, Cioffi M, Amato G & Carella C. Effects of increased thyroxine dosage pre-conception on thyroid function during early pregnancy. European Journal of Endocrinology 2004 151 695-700. (doi:10.1530/eje.0.1510695)
13. Poppe K, Glinoer D, Tournaye H, Schiettecatte J, Devroey P, van Steirteghem A, Haentjens P & Velkeniers B. Impact of ovarian hyperstimulation on thyroid function in women with and without thyroid autoimmunity. Journal of Clinical Endocrinology and Metabolism 2004 89 3808-3812. (doi:10.1210/jc.2004-0105)
14. Vaidya B. Universal screening for thyroid dysfunction in pregnancy? In The Thyroid and Reproduction, 1st edn, ch. 19, pp 153-159. Eds J Lazarus, V Pirags & S Butz. Stuttgart: Georg Thieme Verlag KG, 2009.
15. Vermiglio F, Lo Presti VP, Moleti M, Sidoti M, Tortorella G, Scaffidi G, Castagna MG, Mattina F, Violi MA, Crisà A, Artemisia A & Trimarchi F. Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: a possible novel iodine deficiency disorder in developed countries. Journal of Clinical Endocrinology and Metabolism 2004 89 6054-6060. (doi:10.1210/jc.2004-0571)
16. Haddow JE, Palomaki GE, Allan WC, Williams JR, Knight GJ, Gagnon J, O'Heir CE, Mitchell ML, Hermos RJ, Waisbren SE, Faix JD & Klein RZ. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. New England Journal of Medicine 1999 341 549-555. (doi:10.1056/NEJM199908193410801)
17. Pop VJ, Kuijpens JL, van Baar AL, Verkerk G, van Son MM, de Vijlder JJ, Vulsma T, Wiersinga WM, Drexhage HA & Vader HL. Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy. Clinical Endocrinology 1999 50 149-155. (doi:10.1046/j.1365-2265.1999.00639.x)
18. Casey BM, Dashe JS, Wells CE, McIntire DD, Byrd W, Leveno KJ & Cunningham FG. Subclinical hypothyroidism and pregnancy outcomes. Obstetrics and Gynecology 2005 105 239-245. (doi:10.1097/01.AOG.0000152345.99421.22)
19. Moleti M, Lo Presti VP, Mattina F, Mancuso A, De Vivo A, Giorgianni G, Di Bella B, Trimarchi F & Vermiglio F. Gestational thyroid function abnormalities in conditions of mild iodine deficiency: early screening versus continuous monitoring of maternal thyroid status. European Journal of Endocrinology 2009 160 611-617. (doi:10.1530/EJE-08-0709)
20. Negro R, Schwartz A, Gismondi R, Tinelli A, Mangieri T & Stagnaro-Green A. Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy. Journal of Clinical Endocrinology and Metabolism 2010 95 E44-E48. (doi:10.1210/jc.2010-0340)
21. Thangaratinam S, Tan A, Knox E, Kilby MD, Franklyn J & Coomarasamy A. Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence. BMJ 2011 342 d2616. (doi:10.1136/bmj.d2616)
22. Negro R, Formoso G, Mangieri T, Pezzarossa A, Dazzi D & Hassan H. Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. Journal of Clinical Endocrinology and Metabolism 2006 91 2587-2591. (doi:10.1210/jc.2005-1603)
23. Moleti M, Trimarchi F & Vermiglio F. Doubts and concerns about isolated maternal hypothyroxinemia. Journal of Thyroid Research 2011 2011 463029. (doi:10.4061/2011/463029)
24. Casey BM, Dashe JS, Spong CY, McIntire DD, Leveno KJ & Cunningham GF. Perinatal significance of isolated maternal hypothyroxinemia identified in the first half of pregnancy. Obstetrics and Gynecology 2007 109 1129-1135. (doi:10.1097/01.AOG.0000262054.03531.24)
25. Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA & Rubin HR. Why don't physicians follow clinical practice guidelines? A framework for improvement Journal of the American Medical Association 1999 282 1458-1465. (doi:10.1001/jama.282.15.1458)