Effect of a supplement containing trans-10,cis-12 conjugated linoleic acid on the performance of dairy ewes fed 2 levels of metabolizable protein and at a restricted energy intake

Journal of Dairy Science

Volumn 95, Issue 1, 2012, Pages 109-116

  Weerasinghe, W M P B ^a,e   Wilkinson, R G ^a   Lock, A L ^b   de Veth, M J ^c,f   Bauman, D E ^d   Sinclair, L A ^a  

^a HARPER ADAMS UNIVERSITY   (United Kingdom)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c BASF SE   (Germany)

^d Department of Obstetrics Gynecology   (United States)

^e Veterinary Research Institute   (Sri Lanka)

^f UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Conjugated linoleic acid; Metabolizable protein; Milk fat depression; Sheep

Indexed keywords

CONJUGATED LINOLEIC ACID; FATTY ACID; LIPID; MILK PROTEIN; TRANS 10,CIS 12 CONJUGATED LINOLEIC ACID; TRANS-10,CIS-12-CONJUGATED LINOLEIC ACID; UREA;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CALORIC INTAKE; CHEMISTRY; DIET; DIET SUPPLEMENTATION; DRUG EFFECT; FEMALE; LACTATION; METABOLISM; MILK; PHYSIOLOGY; PROTEIN INTAKE; SHEEP;

ANIMALS; DIET; DIETARY PROTEINS; DIETARY SUPPLEMENTS; ENERGY INTAKE; FATTY ACIDS; FEMALE; LACTATION; LINOLEIC ACIDS, CONJUGATED; LIPIDS; MILK; MILK PROTEINS; SHEEP; UREA;

EID: 84055184154     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2011-4165     Document Type: Article

References (33)

1. Energy and Protein Requirements of Ruminants 1993, Agricultural and Food Research Council, CAB International, Wallingford, UK.
2. Bauman D.E., Griinari J.M. Nutritional regulation of milk fat synthesis. Annu. Rev. Nutr. 2003, 23:203-227.
3. Bauman D.E., Perfield J.W., Harvatine K.J., Baumgard L.H. Regulation of fat synthesis by conjugated linoleic acid: Lactation and the ruminant model. J. Nutr. 2008, 138:403-409.
4. Baumgard L.H., Corl B.A., Dwyer D.A., Bauman D.E. Effect of conjugated linoleic acid (CLA) on tissue response to homeostatic signals and plasma variables associated with lipid metabolism in lactating dairy cows. J. Anim. Sci. 2002, 80:1285-1293.
5. Bernal-Santos G., Perfield J.W., Barbano D.M., Bauman D.E., Overton T.R. Production responses of dairy cows to dietary supplementation with conjugated linoleic acid (CLA) during the transition period and early lactation. J. Dairy Sci. 2003, 86:3218-3228.
6. Cannas A., Pes A., Mancuso R., Vordet B., Nudda A. Effect of dietary energy and protein concentration on the concentration of milk urea nitrogen in dairy ewes. J. Dairy Sci. 1998, 81:499-508.
7. Chouinard P.Y., Corneau L., Barbano D.M., Metzger L.E., Bauman D.E. Conjugated linoleic acids alter milk fatty acid composition and inhibit milk fat secretion in dairy cows. J. Nutr. 1999, 129:1579-1584.
8. Christie W.W. A simple procedure for the rapid transmethylation of glycerolipids and cholesterol esters. J. Lipid Res. 1982, 23:1072-1075.
9. de Veth M.J., Castañeda-Gutierrez E., Dwyer D.A., Pfeiffer A.M., Putnam D., Bauman D.E. Response to conjugated linoleic acid in dairy cows differing in energy and protein status. J. Dairy Sci. 2006, 89:4620-4631.
10. de Veth M.J., Gulati S.K., Luchini N.D., Bauman D.E. Comparison of calcium salts and formaldehyde-protected conjugated linoleic acid in inducing milk fat depression. J. Dairy Sci. 2005, 88:1685-1693.
11. Hara A., Radin N.S. Lipid extraction of tissues with a low-toxicity solvent. Anal. Biochem. 1978, 90:420-426.
12. Harvatine K.J., Boisclair Y.R., Bauman D.E. Recent advances in the regulation of milk fat synthesis. Animal 2009, 3:40-54.
13. Hristov A.N., Price W.J., Shafii B. A meta-analysis examining the relationship among dietary factors, dry matter intake, and milk and milk protein yield in dairy cows. J. Dairy Sci. 2004, 87:2184-2196.
14. Husvéth F., Galamb E., Gaál T., Dublecz K., Wágner L., Pál L. Milk production, milk composition, liver lipid contents and C18 fatty acid composition of milk and liver lipids in Awassi ewes fed a diet supplemented with protected cis-9, trans-11 and trans-10, cis-12 conjugated linoleic (CLA) isomers. Small Rumin. Res. 2010, 94:25-31.
15. Kay J.K., Roche J.R., Moore C.E., Baumgard L.H. Effects of dietary conjugated linoleic acid production and metabolic parameters in transition dairy cows grazing fresh pasture. J. Dairy Res. 2006, 73:367-377.
16. Kolver E.S., Muller L.D. Performance and nutrient intake of high producing Holstein cows consuming pasture or a total mixed ration. J. Dairy Sci. 1998, 81:1403-1411.
17. Lock A.L., Teles B.M., Perfield J.W., Bauman D.E., Sinclair L.A. A conjugated linoleic acid supplement containing trans-10, cis-12 reduces milk fat synthesis in lactating sheep. J. Dairy Sci. 2006, 89:1525-1532.
18. Loor J.J., Ueda K.A., Ferlay A., Chilliard Y., Doreau M. Biohydrogenation, duodenal flow, and intestinal digestibility of trans fatty acids and conjugated linoleic acids in response to dietary forage: concentrate ratio and linseed oil in dairy cows. J. Dairy Sci. 2004, 87:2472-2485.
19. Mackle T.R., Kay J.K., Auldist M.J., McGibbon A.K.H., Philpott B.A., Baumgard L.H., Bauman D.E. Effects of abomasal infusion of conjugated linoleic acid on milk fat concentration and yield from pasture-fed dairy cows. J. Dairy Sci. 2003, 86:644-652.
20. Medeiros S.R., Oliveira D.E., Aroeira L.J.M., McGuire M.A., Bauman D.E., Lanna D.P.D. Effects of dietary supplementation of rumen protected conjugated linoleic acid to grazing cows in early lactation. J. Dairy Sci. 2010, 93:1126-1137.
21. Metcalf J.A., Mansbridge R.J., Blake J.S., Oldham J.D., Newbold J.R. The efficiency of conversion of metabolisable protein into milk true protein over a range of metabolisable protein intakes. Animal 2008, 2:1193-1202.
22. Newbold J.R. Practical applications of the metabolisable protein system. Recent Advances in Animal Nutrition 1994, 231-264. Nottingham University Press, Nottingham, UK. P.C. Garnsworthy, D.J.A. Cole (Eds.).
23. Nocek J.E., Russell J.B. Protein and energy as an integrated system-Relationship of ruminal protein and carbohydrate availability to microbial synthesis and milk production. J. Dairy Sci. 1988, 71:2070-2107.
24. Perfield J.W., Lock A.L., Griinari J.M., Saebo A., Delmonte P., Dwyer D.A., Bauman D.E. Trans-9, cis-11 conjugated linoleic acid reduces milk fat synthesis in lactating dairy cows. J. Dairy Sci. 2007, 90:2211-2218.
25. Robinson J.J. Energy and protein requirements of the ewe. Recent Advances in Animal Nutrition 1987, 187-204. Nottingham University Press, Nottingham, UK. W. Haresign, D.J.A. Cole (Eds.).
26. Russell A.J.F., Doney J.M., Gunn R.G. Subjective assessment of body fat in live sheep. J. Agric. Sci. (Camb.) 1969, 72:351-358.
27. Saebø A., Saebø P.C., Griinari J.M., Shingfield K.J. Effect of abomasal infusions of geometric isomers of 10,12 conjugated synthesis linoleic acid on milk fat in dairy cows. Lipids 2005, 40:823-832.
28. Schauff D.J., Clark J.H., Drackley J.K. Effects of feeding lactating dairy cows diets containing extruded soybeans and calcium salts of long-chain fatty acids. J. Dairy Sci. 1992, 75:3003-3019.
29. Sinclair L.A., Lock A.L., Early R., Bauman D.E. Effects of trans-10, cis-12 conjugated linoleic acid on ovine milk fat synthesis and cheese properties. J. Dairy Sci. 2007, 90:3326-3335.
30. Sinclair L.A., Weerasinghe W.M.P.B., Wilkinson R.G., de Veth M.J., Bauman D.E. A supplement containing trans-10, cis-12 conjugated linoleic acid reduces milk fat yield but does not alter organ weight or body fat deposition in lactating ewes. J. Nutr. 2010, 140:1949-1955.
31. Sukhija P.S., Palmquist D.L. Rapid method for determination of total fatty acid content and composition of feedstuffs and faeces. J. Agric. Food Chem. 1988, 36:1202-1206.
32. Webster A.J.F. The metabolisable protein system for ruminants. Recent Advances in Animal Nutrition 1992, 93-110. Butterworths, London, UK. P.C. Garnsworthy, D.J.A. Cole (Eds.).
33. Wilkinson R.G., Sinclair L.A., Powles J., Minter C.M. Response of lactating ewes grazing grass to variations in effective rumen degradable protein and digestible undegradable protein supply from concentrate supplements. Anim. Sci. 2000, 71:369-379.