Life and death of lymphocytes: A volume regulation affair

Cellular Physiology and Biochemistry

Volumn 28, Issue 6, 2011, Pages 1079-1088

  Bortner, Carl D ^a   Cidlowski, John A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Apoptotic Resistance; Cell Volume Regulation; Osmotic stress; RVI

Indexed keywords

(2 CYCLOPENTYL 6,7 DICHLORO 2 METHYL 1 OXO 5 INDANYLOXY)ACETIC ACID; CALCIMYCIN; CISPLATIN; CYTOCHROME C; DEXAMETHASONE; DOXORUBICIN; FAS LIGAND; GLUCOCORTICOID; GLUTATHIONE; IONOMYCIN; OUABAIN; PHOSPHATIDYLSERINE; THAPSIGARGIN;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL SIZE; CELL SURVIVAL; CELL VIABILITY; DNA FRAGMENTATION; EHRLICH ASCITES TUMOR; EOSINOPHIL; FLOW CYTOMETRY; HEART MUSCLE CELL; HUMAN; HYPEROSMOTIC STRESS; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; LYMPHOCYTE; LYMPHOMA CELL; PHAGOCYTOSIS; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; REVIEW;

EID: 83755206972     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000335864     Document Type: Review

References (51)

1. Elmore S: Apoptosis: A review of programmed cell death. Toxicol Pathol 2007;35:495-516. (Pubitemid 46911891)
2. Van Cruchten S, Van Den Broeck W: Morphological and biochemical aspects of apoptosis, oncosis and necrosis. Anat Histol Embryol 2002;31:214-223.
3. Caron-Leslie L-AM, Cidlowski JA: Similar actions of glucocorticoids and calcium on the regulation of apoptosis in S49 cells. Mol Endocrinol 1991;5:1169-1179.
4. Mann CL, Hughes FM Jr, Cidlowski JA: Delination of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes. Endocrinol 2000;141:528-538. (Pubitemid 32250475)
5. Compton MM, Haskill JS, Cidlowski JA: Analysis of glucocorticoid actions on rat thymocyte deoxyribonucleic acid by fluorescence-activated flow cytometry. Endocrinol 1988;122:2158-2164.
6. Bortner CD, Cidlowski JA: Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes. Am J Physiol 1996;271:C950-C961.
7. Telford WG, Komoriya A, Packard BZ, Bagwell CB: Multiparametric analysis of apoptosis by flow cytometry. Methods Mol Biol 2011;699:203-227.
8. Kerr JFR: A histochemical study of hypertrophy and ischemic injury of rat liver with special reference to changes in lysosomes. J Path Bact 1967;90:419-435.
9. Kerr JFR: Shrinkage necrosis: A distinct mode of cellular death. J Path 1971;105:13-20.
10. Kerr JFR: Shrinkage necrosis of adrenal cortical cells. J Path 1972;107:217-219.
11. Maeno E, Ishizaki Y, Kanaseki T, Hazama A, Okada Y: Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci USA 2000;97:9487-9492. (Pubitemid 30650802)
12. Ernest NJ, Habela CW, Sontheimer H: Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death. J Cell Sci 2008;121:290-297. (Pubitemid 351356700)
13. Poulsen KA, Andersen EC, Hansen CF, Klausen TK, Hougaard C, Lambert IH, Hoffmann EK: Deregulation o apoptotic volume decrease and ionic movements in multidrug-resistant tumor cells: role of chloride channels. Am J Physiol 2010;298:C14-C25.
14. Hoffmann EK, Lambert IH, Pedersen SF: Physiology of cell volume regulation in vertebrates. Physiol Rev 2009;89:193-277.
15. Panayiotidis MI, Bortner CD, Cidlowski JA: On the mechanisms of ionic regulation of apoptosis: would the Na+/K+-ATPase please stand up Acta Physiol 2006;187:205-215. (Pubitemid 43828778)
16. Bortner CD, Hughes FM Jr, Cidlowski JA: A primary role for K+ and Na+ efflux in the activation of apoptosis. J Biol Chem 1997;272:32436-32442. (Pubitemid 28011927)
17. Hughes FM Jr, Bortner CD, Purdy GD, Cidlowski JA: Intracellular K+ suppresses the activation of apoptosis in lymphocytes. J Biol Chem 1997;272: 30567-30576. (Pubitemid 27512272)
18. Cain K, Langlais C, Sun XM, Brown DG, Cohen GM: Physiological concentrations of K+ inhibit cytochrome c-dependent formation of the apoptosome. J Biol Chem 2001;276:41985-41990.
19. Thompson GJ, Langlais C, Cain K, Conley EC, Cohen GM: Elevated extracellular [K+] inhibits death-receptorand chemical-mediated apoptosis prior to caspase activation and cytochrome c release. Biochem J 2001;357:137-145. (Pubitemid 32642911)
20. Yu SP, Canzoniero LM, Choi DW: Ion homeostasis and apoptosis. Curr Opin Cell Biol 2001;13:405-411. (Pubitemid 32709761)
21. Lang F, Shumilina E, Ritter M, Gulbins E, Vereninov A, Huber SM: Ion channels and cell volume in the regulation of cell proliferation and apoptotic cell death. Contrib Nephrol 2006;152:142-160. (Pubitemid 44672106)
22. Bortner CD, Cidlowski JA: Cell shrinkage and monovalent cation fluxes: role in apoptosis. Arch Biochem Biophys 2007;462:176-188. (Pubitemid 46863418)
23. Bortner CD, Gomez-Angelats M, Cidlowski JA: Plasma membrane depolarization with repolarization in an early molecular event in anti-Fas-induced apoptosis. J Biol Chem 2001;276:4304-4314.
24. Bortner CD, Sifre MI, Cidlowski JA: Cationic gradient reversal and cytoskeleton-independent volume regulatory pathways define and early stage of apoptosis. J Biol Chem 2008;283:7219-7229.
25. Bortner CD, Cidlowski JA: Uncoupling cell shrinkage from apoptosis reveals that Na+ influx is required for volume loss during programmed cell death. J Biol Chem 2003;278:39176-39184. (Pubitemid 37221820)
26. Mann CL, Cidlowski JA: Glucocorticoids regulate plasma membrane potential during rat thymocyte apoptosis in vivo and in vitro. Endocrinol 2001;142:421-429. (Pubitemid 32183704)
27. Mann CL, Bortner CD, Jewell CM, Cidlowski JA: Glucocorticoid-induced plasma membrane depolarization during thymocyte apoptosis: Association with cell shrinkage and degradation of the Na+/K+-Adenosine Triphosphatase. Endocrinol 2001;142:5059-5068. (Pubitemid 33131931)
28. Chimote AA, Adragna NC, Lauf PK: Ion transport in a human lens epithelial cell line exposed to hyposmotic and apoptotic stress. J Cell Physiol 2010;223:110-122.
29. Beauvais F, Michel L, Dubertret L: Human eosinophils in culture undergo a striking and rapid shrinkage during apoptotis. Role of K+ channels. J Leukoc Biol 1995;57:851-855.
30. Klassen NV, Walker PR, Ross CK, Cygler J, Lach B: Two-stage cell shrinkage and the OER for radiation-induced apoptosis of rat thymocytes. Int J Radiat Biol 1993;64:571-581. (Pubitemid 23350459)
31. Schwartzman RA, Cidlowski JA: Mechanism of tissue-specific induction of internucleosomal deoxyribonucleic acid cleavage activity and apoptosis by glucocorticoids. Endocrinol 1993;133:591-599. (Pubitemid 23238868)
32. Ajiro K, Bortner CD, Westmoreland J, Cidlowski JA: An endogenous calciumdependent, caspase-independent intranuclear degradation pathway in thymocyte nuclei: antagonism by physiological concentration of K+ ions. Exp Cell Res 2008;314:1237-1249.
33. Bortner CD, Cidlowski JA: Caspase independent/dependent regulation of K+, cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis. J Biol Chem 1999;274:21953-21962.
34. Scoltock AB, Cidlowski JA: Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: the role of caspase inhibition. Exp Cell Res 2004;297:212-223. (Pubitemid 38759574)
35. Vu CCQ, Bortner CD, Cidlowski JA: Differential involvement of initiator caspases in apoptotic volume decrease and potassium efflux during Fas-and UVinduced cell death. J Biol Chem 2001;276:37602-37611.
36. Shimizu T, Numata T, Okada Y: A role of reactive oxygen species in apoptotic activation of volume-sensitive Clchannel. Proc Natl Acad Sci USA 2004;101:6770-6773. (Pubitemid 38586049)
37. Heimlich G, Cidlowski JA: Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells. J Biol Chem 2006;281:2232-2241. (Pubitemid 43845814)
38. d' Anglemont de Tassigny A, Souktani R, Henry P, Ghaleh B, Berdeaux A: Volumesensitive chloride channels (ICl,vol) mediate doxorubincin-induced apoptosis through apoptotic volume decrease in cardiomyocytes. Fundam Clin Pharmacol 2004;18:531-538. (Pubitemid 39468961)
39. Gomez-Angelats M, Bortner CD, Cidlowski JA: Protein kinase C (PKC) inhibits Fas receptor-induced apoptosis through modulation of the loss of K+ and cell shrinkage. J Biol Chem 2001;276:44944-44952.
40. Franco R, Cidlowski JA: Apoptosis and glutathione: beyond and antioxidant. Cell Death Differ 2009;16:1303-1314.
41. Circu ML, Aw TY: Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med 2010;48:749-762.
42. Circu ML, Aw TY: Glutathione and apoptosis. Free Radic Res 2008;42:689-706.
43. Franco R, Schoneveld OJ, Pappa A, Panayiotidis MI: The central role of glutathione in the pathophysiology of human diseases. Arch Physiol Biochem 2007;113:234-258.
44. Franco R, Cidlowski JA: SLCO/OATPlike transport of glutathione in FasLinduced apoptosis. J Biol Chem 2006;281:29542-29557.
45. Franco R, Panayiotidis MI, Cidlowski JA: Glutathione depletion is necessary for apoptosis in lymphoid cell independent of reactive oxygen species formation. J Biol Chem 2007;282:30452-30465. Bortner/Cidlowski (Pubitemid 350035221)
46. Franco R, DeHaven WI, Sifre MI, Bortner CD, Cidlowski JA: Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis. J Biol Chem 2008;283:36071-36087.
47. Lang F, Busch GL, Ritter M, Volkl H, Waldegger S, Gulbins E, Haussinger D: Functional significance of cell volume regulatory mechanisms. Physiol Rev 1998;78:247-306. (Pubitemid 28070981)
48. Okada Y: Ion channels and transporters involved in cell volume regulation and sensor mechanisms. Cell Biochem Biophys 2004;41:233-258. (Pubitemid 41270759)
49. Maeno E, Takahashi N, Okada Y: Dysfunction of regulatory volume increase is a key component of apoptosis. FEBS Lett 2006;580:6513-6517. (Pubitemid 44750945)
50. Subramanyam M, Takahashi N, Hasegawa Y, Mohri T, Okada Y: Inhibition of protein kinase Akt1 by apoptosis signalregulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase. J Biol Chem 2010;285:6109-6117.
51. Grinstein S, Clarke CA, Rothstein A: Activation of Na+/H+ exchange in lymphocytes by osmotically induced volume changes and by cytoplasmic acidification. J Gen Physiol 1983;82:619-638. (Pubitemid 14211705)