Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 1, 2012, Pages

  Rancourt, Raymond C ^a   Veress, Livia A ^a   Guo, Xiaoling ^a   Jones, Tara N ^a   Hendry Hofer, Tara B ^a   White, Carl W ^a  

^a DEPARTMENT OF MEDICINE   (United States)

Author keywords

Lactadherin; Rat; Tissue factor pathway inhibitor

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7; LACTADHERIN; MUSTARD GAS DERIVATIVE; RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR; SULFUR MUSTARD ANALOG 2 CHLOROETHYL ETHYL SULFIDE; THROMBOPLASTIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; BRONCHUS MUCOSA; CELL SURFACE; CELL VIABILITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LUNG INJURY; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY EPITHELIUM;

AIRWAY OBSTRUCTION; ANIMALS; ANTIGENS, SURFACE; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE, TRANSFORMED; CHEMICAL WARFARE AGENTS; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FACTOR VII; FACTOR XA; HUMANS; INHALATION EXPOSURE; MALE; MILK PROTEINS; MUSTARD GAS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; THROMBOPLASTIN; TIME FACTORS;

EID: 83755196225     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00306.2010     Document Type: Article

References (43)

1. Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, Beale R, Svoboda P, Laterre PF, Simon S, Light B, Spapen H, Stone J, Seibert A, Peckelsen C, De Deyne C, Postier R, Pettilä V, Artigas A, Percell SR, Shu V, Zwingelstein C, Tobias J, Poole L, Stolzenbach JC, Creasey AA; OPTIMIST Trial Study Group. Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA 290: 238-247, 2003.
2. Ait-Oufella H, Kinugawa K, Zoll J, Simon T, Boddaert J, Heeneman S, Blanc-Brude O, Barateau V, Potteaux S, Merval R, Esposito B, Teissier E, Daemen MJ, Lesèche G, Boulanger C, Tedgui A, Mallat Z. Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice. Circulation 115: 2168-2177, 2007.
3. Allon N, Amir A, Manisterski E, Rabinovitz I, Dachir S, Kadar T. Inhalation exposure to sulfur mustard in the guinea pig model: Clinical, biochemical and histopathological characterization of respiratory injuries. Toxicol Appl Pharmacol 241: 154-162, 2009.
4. Andersen MH, Berglund L, Rasmussen JT, Petersen TE. Bovine PAS-6/7 binds alpha v beta 5 integrins and anionic phospholipids through two domains. Biochemistry 36: 5441-5446, 1997.
5. Bach RR. Mechanism of tissue factor activation on cells. Blood Coagul Fibrinolysis 9: S37-S43, 1998.
6. Bach RR. Tissue factor encryption. Arterioscler Thromb Vasc Biol 26: 456-461, 2006.
7. Bastarache JA, Wang L, Wang Z, Albertine KH, Matthay MA, Ware LB. Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity. Am J Physiol Lung Cell Mol Physiol 294: L874-L881, 2008.
8. Carraway MS, Welty-Wolf KE, Miller DL, Ortel TL, Idell S, Ghio AJ, Petersen LC, Piantadosi CA. Blockade of tissue factor: treatment for organ injury in established sepsis. Am J Respir Crit Care Med 167: 1200-1209, 2003.
9. Crathorn AR, Roberts JJ. Mechanism of the cytotoxic action of alkylating agents in mammalian cells and evidence for the removal of alkylated groups from deoxyribonucleic acid. Nature 211: 150-153, 1966.
10. Creasey AA, Chang AC, Feigen L, Wun TC, Taylor FB, Hinshaw LB. Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock. J Clin Invest 91: 2850-2860, 1993.
11. Dillman JF, Phillips CS, Dorsch LM, Croxton MD, Hege AI, Sylvester AJ, Moran TS, Sciuto AM. Genomic analysis of rodent pulmonary tissue following bis-(2-chloroethyl) sulfide exposure. Chem Res Toxicol 18: 28-34, 2005.
12. Enkhbaatar P, Cox RA, Traber LD, Westphal M, Aimalohi E, Morita N, Prough DS, Herndon DN, Traber DL. Aerosolized anticoagulants ameliorate acute lung injury in sheep after exposure to burn and smoke inhalation. Crit Care Med 35: 2805-2810, 2007.
13. Gautum A, Vijayaraghavan R, Sharma M, Ganesan K. Comparative toxicity studies of sulfur mustard (2,2=-dichloro diethyl sulfide) and monofunctional sulfur mustard (2-chloroethyl ethyl sulfide), administered through various routes in mice. J Med CBR Def 4: 1-21, 2006.
14. Greeno EW, Bach RR, Moldow CF. Apoptosis is associated with increased cell surface tissue factor procoagulant activity. Lab Invest 75: 281-289, 1996.
15. Hajj R, Baranek T, Le Naour R, Lesimple P, Puchelle E, Coraux C. Basal cells of the human adult airway surface epithelium retain transitamplifying cell properties. Stem Cells 25: 139-48, 2007.
16. Han S, Espinoza LA, Liao H, Boulares AH, Smulson ME. Protection by antioxidants against toxicity and apoptosis induced by the sulphur mustard analog 2-chloroethylethyl sulphide (CEES) in Jurkat T cells and normal human lymphocytes. Br J Pharmacol 141: 795-802, 2004.
17. Herriot RM, Anson ML, Northrop J. Reaction of enzymes and proteins with mustard gas (bis(beta-chloroethyl)sulfide). J Gen Physiol 30: 185-210, 1946.
18. Hosseini K, Moradi A, Mansouri A, Vessal K. Pulmonary manifestations of mustard gas injury: a review of 61 cases. Ir J Med Sci 14: 20-26, 1989.
19. Hugel B, Socié G, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML. Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia. Blood 93: 3451-3456, 1999.
20. Idell S, Peters J, James KK, Fair DS, Coalson JJ. Local abnormalities of coagulation and fibrinolytic pathways that promote alveolar fibrin deposition in the lungs of baboons with diffuse alveolar damage. J Clin Invest 84: 181-193, 1989.
21. Idell S, Peterson BT, Gonzalez KK, Gray LD, Bach R, McLarty J, Fair DS. Local abnormalities of coagulation and fibrinolysis and alveolar fibrin deposition in sheep with oleic acid-induced lung injury. Am Rev Respir Dis 138: 1282-1294, 1998.
22. Idell S. Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med 31: S213-S220, 2003.
23. Laterre PF, Opal SM, Abraham E, LaRosa SP, Creasey AA, Xie F, Poole L, Wunderink RG. A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia. Crit Care 13: R36, 2009.
24. Lawley PD, Brookes P. Molecular mechanism of the cytotoxic action of difunctional alkylating agents and of resistance to this action. Nature 206: 480-483, 1965.
25. Lechner D, Kollars M, Gleiss A, Kyrle PA, Weltermann A. Chemotherapy induced thrombin generation via procoagulant endothelial microparticles is independent of tissue factor activity. J Thromb Haemost 5: 520-527, 2007.
26. McClintock SD, Hoesel LM, Das SK, Till GO, Neff T, Kunkel RG, Smith MG, Ward PA. Attenuation of half sulfur mustard gas-induced acute lung injury in rats. J Appl Toxicol 26: 126-131, 2006.
27. Mozier NM, Hoffman JL. Biosynthesis and urinary excretion of methyl sulfonium derivatives of the sulfur mustard analog, 2 chloroethyl sulfide, and other thioethers. FASEB J 4: 3329-3333, 1990.
28. Murakami K, McGuire R, Cox RA, Jodoin JM, Bjertnaes LJ, Katahira J, Traber LD, Schmalstieg FC, Hawkins HK, Herndon DN, Traber DL. Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep. Shock 18: 236-241, 2002.
29. Nemerson Y. The tissue factor of blood coagulation. Semin Hematol 29: 170-176, 1992.
30. Papirmeister B, Feister AJ, Robinson SI, Ford RD. Medical Defense Against Mustard Gas: Toxic Mechanisms and Pharmacological Implications. Boca Raton, FL: CRC, 1991, p. 106.
31. Rothberger H, McGee MP, Lee TK. Tissue factor activity. A marker of alveolar macrophage maturation in rabbits. Effects of granulomatous pneumonitis. J Clin Invest 73: 1524-1531, 1984.
32. Rusch GM, Garrett R, Tobin P, Falke E, Lu PY. The development of acute exposure guideline levels for hazardous substances. Drug Chem Toxicol 25: 339-348, 2002.
33. Shi J, Gilbert GE. Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid binding sites. Blood 101: 2628-2636, 2003.
34. Somani SM, Babu SR. Toxicodynamics of sulfur mustard. Int J Clin Pharmacol Ther Toxicol 27: 419-435, 1989.
35. Stampfuss JJ, Censarek P, Bein D, Schrör K, Grandoch M, Naber C, Weber AA. Membrane environment rather than tissue factor expression determines thrombin formation triggered by monocytic cells undergoing apoptosis. J Leukoc Biol 83: 1379-1381, 2008.
36. Stewart JC. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal Biochem 104: 4-10, 1980.
37. Szinicz L. History of chemical and biological warfare agents. Toxicology 214: 167-181, 2005.
38. Traber DL, Hawkins HK. Airway obstruction in sheep with burn and smoke inhalation injuries. Am J Respir Cell Mol Biol 29: 295-302, 2003.
39. Veress LA, O'Neill HC, Hendry-Hofer TB, Loader JE, Rancourt RC, White CW. Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation. Am J Respir Crit Care Med 182: 1352-1361, 2010.
40. Warthin AS, Weller CV. The lesions of the respiratory and gastrointestinal tract produced by mustard gas (dichlorethyl sulphide). J Lab Clin Med 4: 229-264, 1919.
41. Winternitz MC. Anatomical changes in the respiratory tract initiated by irritating gases. Military Surgeon 44: 476-493, 1919.
42. Yang YC, Szafraniec LL, Beaudry WT, Ward JR. Kinetics and mechanism of the hydrolysis of 2-chloroethyl sulfides. J Org Chem 14: 3293-3297, 1988.
43. Zhang Z, Peters BP, Monteiro-Riviere NA. Assessment of sulfur mustard interaction with basement membrane components. Cell Biol Toxicol 11: 89-101, 1995.