-
1
-
-
26444539817
-
Genetic control of isoniazid metabolism in man
-
Evans DA, Manley KA, McKusick VA. Genetic control of isoniazid metabolism in man. Br. Med. J. 2, 485-491 (1960).
-
(1960)
Br. Med. J.
, vol.2
, pp. 485-491
-
-
Evans, D.A.1
Manley, K.A.2
McKusick, V.A.3
-
2
-
-
0021813284
-
N-acetylation pharmacogenetics
-
Weber WW, Hein DW. N-acetylation pharmacogenetics. Pharmacol. Rev. 37, 25-79 (1985). (Pubitemid 15081093)
-
(1985)
Pharmacological Reviews
, vol.37
, Issue.1
, pp. 25-79
-
-
Weber, W.W.1
Hein, D.W.2
-
3
-
-
0344759188
-
Arylamine N-acetyltransferase activity in man
-
DOI 10.1081/DMR-100101932
-
Cascorbi I, Brockmoller J, Mrozikiewicz PM, Muller A, Roots I. Arylamine N-acetyltransferase activity in man. Drug Metab. Rev. 31, 489-502 (1999). (Pubitemid 29222674)
-
(1999)
Drug Metabolism Reviews
, vol.31
, Issue.2
, pp. 489-502
-
-
Cascorbi, I.1
Brockmoller, J.2
Mrozikiewicz, P.M.3
Muller, A.4
Roots, I.5
-
4
-
-
0025948280
-
Molecular mechanism of slow acetylation of drugs and carcinogens in humans
-
Blum M, Demierre A, Grant DM, Heim, M, Meyer UA. Molecular mechanism of slow acetylation of drugs and carcinogens in humans. Proc. Natl Acad. Sci. USA 88, 5237-5241 (1991). (Pubitemid 21914719)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.12
, pp. 5237-5241
-
-
Blum, M.1
Demierre, A.2
Grant, D.M.3
Heim, M.4
Meyer, U.A.5
-
6
-
-
26444618665
-
Arylamine N-acetyltransferases: What we learn from genes and genomes
-
DOI 10.1080/03602530500251204
-
Boukouvala S, Fakis G. Arylamine N-acetyltransferases: what we learn from genes and genomes. Drug Metab. Rev. 37, 511-564 (2005). (Pubitemid 41434161)
-
(2005)
Drug Metabolism Reviews
, vol.37
, Issue.3
, pp. 511-564
-
-
Boukouvala, S.1
Fakis, G.2
-
7
-
-
0033824239
-
Pharmacogenetics of the human arylamine N-acetyltransferases
-
Grant DM, Goodfellow GH, Sugamori K, Durette K. Pharmacogenetics of the human arylamine N-acetyltransferases. Pharmacology 61, 204-211 (2000).
-
(2000)
Pharmacology
, vol.61
, pp. 204-211
-
-
Grant, D.M.1
Goodfellow, G.H.2
Sugamori, K.3
Durette, K.4
-
8
-
-
56349101750
-
Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms
-
Sim E, Lack N, Wang CJ et al. Arylamine N-acetyltransferases: structural and functional implications of polymorphisms. Toxicology 254, 170-183 (2008).
-
(2008)
Toxicology
, vol.254
, pp. 170-183
-
-
Sim, E.1
Lack, N.2
Wang, C.J.3
-
9
-
-
0033960051
-
Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms
-
Hein DW, Doll MA, Fretland AJ et al. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol. Biomarkers Prev. 9, 29-42 (2000). (Pubitemid 30062907)
-
(2000)
Cancer Epidemiology Biomarkers and Prevention
, vol.9
, Issue.1
, pp. 29-42
-
-
Hein, D.W.1
Doll, M.A.2
Fretland, A.J.3
Leff, M.A.4
Webb, S.J.5
Xiao, G.H.6
Devanaboyina, U.-S.7
Nangju, N.A.8
Feng, Y.9
-
10
-
-
47749085094
-
Polymorphisms of human N-acetyltransferases and cancer risk
-
DOI 10.2174/138920008784892083
-
Agundez JA. Polymorphisms of human N-acetyltransferases and cancer risk. Curr. Drug Metab. 9, 520-531 (2008). (Pubitemid 352025183)
-
(2008)
Current Drug Metabolism
, vol.9
, Issue.6
, pp. 520-531
-
-
Agundez, J.A.G.1
-
11
-
-
47749095050
-
Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2
-
DOI 10.2174/138920008784892065
-
Walraven JM, Zang Y, Trent JO, Hein DW. Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2. Curr. Drug Metab. 9, 471-486 (2008). (Pubitemid 352025179)
-
(2008)
Current Drug Metabolism
, vol.9
, Issue.6
, pp. 471-486
-
-
Walraven, J.M.1
Zang, Y.2
Tent, J.O.3
Hein, D.W.4
-
12
-
-
67649243788
-
N-acetyltransferase SNPs: Emerging concepts serve as a paradigm for understanding complexities of personalized medicine
-
Hein DW. N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Expert Opin. Drug Metab. Toxicol. 5, 353-366 (2009).
-
(2009)
Expert Opin. Drug Metab. Toxicol.
, vol.5
, pp. 353-366
-
-
Hein, D.W.1
-
13
-
-
4444258254
-
Impact of misclassification in genotype-exposure interaction studies: Example of N-acetyltransferase 2 (NAT2), smoking, and bladder cancer
-
Deitz AC, Rothman N, Rebbeck TR et al. Impact of misclassification in genotype-exposure interaction studies: example of N-acetyltransferase 2 (NAT2), smoking, and bladder cancer. Cancer Epidemiol. Biomarkers Prev. 13, 1543-1546 (2004). (Pubitemid 39202325)
-
(2004)
Cancer Epidemiology Biomarkers and Prevention
, vol.13
, Issue.9
, pp. 1543-1546
-
-
Deitz, A.C.1
Rothman, N.2
Rebbeck, T.R.3
Hayes, R.B.4
Chow, W.-H.5
Zheng, W.6
Hein, D.W.7
Garcia-Closas, M.8
-
14
-
-
0028829841
-
Determination of human NAT2 acetylator genotype by restriction fragment-length polymorphism and allele-specific amplification
-
Doll MA, Fretland AJ, Deitz AC, Hein DW. Determination of human NAT2 acetylator genotype by restriction fragment-length polymorphism and allele-specific amplification. Anal. Biochem. 231, 413-420 (1995).
-
(1995)
Anal. Biochem.
, vol.231
, pp. 413-420
-
-
Doll, M.A.1
Fretland, A.J.2
Deitz, A.C.3
Hein, D.W.4
-
15
-
-
84947899485
-
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
-
Rothman N, Garcia-Closas M, Chatterjee N et al. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat. Genet. 42, 978-984 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 978-984
-
-
Rothman, N.1
Garcia-Closas, M.2
Chatterjee, N.3
-
16
-
-
79955484827
-
A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background
-
Garcia-Closas M, Hein DW, Silverman D et al. A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background. Pharmacogenet. Genomics 21, 231-236 (2011).
-
(2011)
Pharmacogenet. Genomics
, vol.21
, pp. 231-236
-
-
Garcia-Closas, M.1
Hein, D.W.2
Silverman, D.3
-
17
-
-
77954913118
-
Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes
-
Doll MA, Zang Y, Moeller T, Hein DW. Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes. J. Pharmacol. Exp. Ther. 334, 540-544 (2010).
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.334
, pp. 540-544
-
-
Doll, M.A.1
Zang, Y.2
Moeller, T.3
Hein, D.W.4
-
18
-
-
0035169575
-
Comprehensive human NAT2 genotype method using single nucleotide polymorphism-specific polymerase chain reaction primers and fluorogenic probes
-
DOI 10.1006/abio.2000.4892
-
Doll MA, Hein, DW. Comprehensive human NAT2 genotype method using single nucleotide polymorphism-specific polymerase chain reaction primers and fluorogenic probes. Anal. Biochem. 288, 106-108 (2001). (Pubitemid 32047653)
-
(2001)
Analytical Biochemistry
, vol.288
, Issue.1
, pp. 106-108
-
-
Doll, M.A.1
Hein, D.W.2
-
19
-
-
33645117090
-
N-acetyltransferase 2 genetic polymorphism: Effects of carcinogen and haplotype on urinary bladder cancer risk
-
Hein DW. N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk. Oncogene 25, 1649-1658 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 1649-1658
-
-
Hein, D.W.1
-
20
-
-
0032967592
-
Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse
-
Leff MA, Epstein PN, Doll MA et al. Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse. J. Pharmacol. Exp. Ther. 290, 182-187 (1999). (Pubitemid 29302318)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.290
, Issue.1
, pp. 182-187
-
-
Leff, M.A.1
Epstein, P.N.2
Doll, M.A.3
Fretland, A.J.4
Devanaboyina, U.-S.5
Rustan, T.D.6
Hein, D.W.7
-
22
-
-
33646527381
-
The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population
-
Chen B, Zhang WX, Cai WM. The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population. Eur. J. Clin. Pharmacol. 62, 355-359 (2006).
-
(2006)
Eur. J. Clin. Pharmacol.
, vol.62
, pp. 355-359
-
-
Chen, B.1
Zhang, W.X.2
Cai, W.M.3
-
23
-
-
0025364134
-
Correlation between acetylator phenotypes and genotypes of polymorphic arylamine N-acetyltransferase in human liver
-
Deguchi T, Mashimo M, Suzuki T. Correlation between acetylator phenotypes and genotypes of polymorphic arylamine N-acetyltransferase in human liver. J. Biol. Chem. 265, 12757-12760 (1990). (Pubitemid 20234207)
-
(1990)
Journal of Biological Chemistry
, vol.265
, Issue.22
, pp. 12757-12760
-
-
Deguchi, T.1
Mashimo, M.2
Suzuki, T.3
-
24
-
-
0030914911
-
Trimodality of isoniazid elimination: Phenotype and genotype in patients with tuberculosis
-
Parkin DP, Vandenplas S, Botha FJ et al. Trimodality of isoniazid elimination: phenotype and genotype in patients with tuberculosis. Am. J. Respir. Crit. Care Med. 155, 1717-1722 (1997). (Pubitemid 27216683)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.155
, Issue.5
, pp. 1717-1722
-
-
Parkin, D.P.1
Vandenplas, S.2
Botha, F.J.H.3
Vandenplas, M.L.4
Seifart, H.I.5
Van Helden, P.D.6
Van Der Walt, B.J.7
Donald, P.R.8
Van Jaarsveld, P.P.9
-
25
-
-
0030885096
-
A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid
-
Smith CA, Wadelius M, Gough AC, Harrison DJ, Wolf CR, Rane A. A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid. J. Med. Genet. 34, 758-760 (1997). (Pubitemid 27406199)
-
(1997)
Journal of Medical Genetics
, vol.34
, Issue.9
, pp. 758-760
-
-
Smith, C.A.D.1
Wadelius, M.2
Gough, A.C.3
Harrison, D.J.4
Wolf, C.R.5
Rane, A.6
-
26
-
-
20944449543
-
Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?
-
DOI 10.1128/AAC.49.5.1733-1738.2005
-
Kinzig-Schippers M, Tomalik-Scharte D, Jetter A et al. Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses? Antimicrob. Agents Chemother. 49, 1733-1738 (2005). (Pubitemid 40631582)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.5
, pp. 1733-1738
-
-
Kinzig-Schippers, M.1
Tomalik-Scharte, D.2
Jetter, A.3
Scheidel, B.4
Jakob, V.5
Rodamer, M.6
Cascorbi, I.7
Doroshyenko, O.8
Sorgel, F.9
Fuhr, U.10
-
27
-
-
67651091328
-
Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population
-
Ma JJ, Liu CG, Li JH, Cao XM, Sun SL, Yao X. Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population. Clin. Chim. Acta 407, 30-35 (2009).
-
(2009)
Clin. Chim. Acta
, vol.407
, pp. 30-35
-
-
Ma, J.J.1
Liu, C.G.2
Li, J.H.3
Cao, X.M.4
Sun, S.L.5
Yao, X.6
-
29
-
-
0029163589
-
Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: Correlation with phenotypic activity
-
Cascorbi I, Drakoulis N, Brockmoller J, Maurer A, Sperling K, Roots I. Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity. Am. J. Hum. Genet. 57, 581-592 (1995).
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 581-592
-
-
Cascorbi, I.1
Drakoulis, N.2
Brockmoller, J.3
Maurer, A.4
Sperling, K.5
Roots, I.6
-
30
-
-
0023930708
-
Genetic control of acetyl coenzyme A-dependent arylamine N-acetyltransferase, hydrazine N-acetyltransferase, and N-hydroxy-arylamine O-acetyltransferase enzymes in C57BL/6J, A/J, AC57F1, and the rapid and slow acetylator A.B6 and B6.A congenic inbred mouse
-
Hein DW, Trinidad A, Yerokun T, Ferguson RJ, Kirlin WG, Weber WW. Genetic control of acetyl coenzyme A-dependent arylamine N-acetyltransferase, hydrazine N-acetyltransferase, and N-hydroxy-arylamine O-acetyltransferase enzymes in C57BL/6J, A/J, AC57F1, and the rapid and slow acetylator A.B6 and B6.A congenic inbred mouse. Drug Metab. Dispos. 16, 341-347 (1988).
-
(1988)
Drug Metab. Dispos.
, vol.16
, pp. 341-347
-
-
Hein, D.W.1
Trinidad, A.2
Yerokun, T.3
Ferguson, R.J.4
Kirlin, W.G.5
Weber, W.W.6
-
31
-
-
0026319473
-
Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian-hamsters congenic at the polymorphic acetyltransferase locus
-
Hein DW, Rustan TD, Bucher KD, Miller LS. Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian-hamsters congenic at the polymorphic acetyltransferase locus. J. Pharmacol. Exp. Ther. 259, 699-704 (1991).
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.259
, pp. 699-704
-
-
Hein, D.W.1
Rustan, T.D.2
Bucher, K.D.3
Miller, L.S.4
-
32
-
-
0028301762
-
Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): Acetylator genotype-dependent N- and O- acetylation of arylamine carcinogens
-
DOI 10.1006/taap.1994.1003
-
Hein DW, Doll MA, Rustan TD, Gray K, Ferguson RJ, Feng Y. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens. Toxicol. Appl. Pharmacol. 124, 16-24 (1994). (Pubitemid 24079030)
-
(1994)
Toxicology and Applied Pharmacology
, vol.124
, Issue.1
, pp. 16-24
-
-
Hein, D.W.1
Doll, M.A.2
Rustan, T.D.3
Gray, K.4
Ferguson, R.J.5
Feng, Y.6
-
33
-
-
0026077162
-
Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver
-
Hein DW, Rustan TD, Bucher KD, Martin WJ, Furman EJ. Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver. Drug Metab. Dispos. 19, 933-937 (1991).
-
(1991)
Drug Metab. Dispos.
, vol.19
, pp. 933-937
-
-
Hein, D.W.1
Rustan, T.D.2
Bucher, K.D.3
Martin, W.J.4
Furman, E.J.5
-
34
-
-
57349197905
-
Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat
-
Hein DW, Bendaly J, Neale JR, Doll MA. Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat. Drug Metab. Dispos. 36, 2452-2459 (2008).
-
(2008)
Drug Metab. Dispos.
, vol.36
, pp. 2452-2459
-
-
Hein, D.W.1
Bendaly, J.2
Neale, J.R.3
Doll, M.A.4
-
35
-
-
0025967717
-
Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
-
Grant DM, Blum M, Beer M, Meyer UA. Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes. Mol. Pharmacol. 39, 184-191 (1991).
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 184-191
-
-
Grant, D.M.1
Blum, M.2
Beer, M.3
Meyer, U.A.4
-
36
-
-
0027281895
-
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
-
Hein DW, Doll MA, Rustan TD et al. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 14, 1633-1638 (1993). (Pubitemid 23249371)
-
(1993)
Carcinogenesis
, vol.14
, Issue.8
, pp. 1633-1638
-
-
Hein, D.W.1
Doll, M.A.2
Rustan, T.D.3
Gray, K.4
Feng, Y.5
Ferguson, R.J.6
Grant, D.M.7
-
37
-
-
0028286844
-
Molecular genetics of human polymorphic N-acetyltransferase: Enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes
-
Hein DW, Ferguson RJ, Doll MA, Rustan TD, Gray K. Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes. Hum. Mol. Genet. 3, 729-734 (1994). (Pubitemid 24148616)
-
(1994)
Human Molecular Genetics
, vol.3
, Issue.5
, pp. 729-734
-
-
Hein, D.W.1
Ferguson, R.J.2
Doll, M.A.3
Rustan, T.D.4
Gray, K.5
-
38
-
-
0029117480
-
Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: Effects of 7 specific NAT2 nucleic acid substitutions
-
Hein DW, Doll MA, Rustan TD, Ferguson RJ. Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions. Cancer Res. 55, 3531-3536 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 3531-3536
-
-
Hein, D.W.1
Doll, M.A.2
Rustan, T.D.3
Ferguson, R.J.4
-
40
-
-
0035052559
-
Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms
-
DOI 10.1097/00008571-200104000-00004
-
Fretland AJ, Leff MA, Doll MA, Hein DW. Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. Pharmacogenetics 11, 207-215 (2001). (Pubitemid 32319870)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.3
, pp. 207-215
-
-
Fretland, A.J.1
Leff, M.A.2
Doll, M.A.3
Hein, D.W.4
-
41
-
-
33746351519
-
Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens
-
DOI 10.1002/ijc.21957
-
Hein DW, Fretland AJ Doll MA. Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens. Int. J. Cancer 119, 1208-1211 (2006). (Pubitemid 44116930)
-
(2006)
International Journal of Cancer
, vol.119
, Issue.5
, pp. 1208-1211
-
-
Hein, D.W.1
Fretland, A.J.2
Doll, M.A.3
-
42
-
-
9244240756
-
341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation
-
DOI 10.1097/00008571-200411000-00002
-
Zang Y, Zhao S, Doll MA, States JC, Hein DW. The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation. Pharmacogenetics 14, 717-723 (2004). (Pubitemid 39552786)
-
(2004)
Pharmacogenetics
, vol.14
, Issue.11
, pp. 717-723
-
-
Zang, Y.1
Zhao, S.2
Doll, M.A.3
States, J.C.4
Hein, D.W.5
-
43
-
-
34548063942
-
Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2
-
DOI 10.1093/carcin/bgm085
-
Zang Y, Doll MA, Zhao S, States JC, Hein DW. Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2. Carcinogenesis 28, 1665-1671 (2007). (Pubitemid 47289027)
-
(2007)
Carcinogenesis
, vol.28
, Issue.8
, pp. 1665-1671
-
-
Zang, Y.1
Doll, M.A.2
Zhao, S.3
States, C.J.4
Hein, D.W.5
-
44
-
-
80052735831
-
Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype
-
Selinski S, Blaszkewicz M, Lehmann ML et al. Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype. Pharmacogenet. Genomics 21(10), 673-678 (2011).
-
(2011)
Pharmacogenet. Genomics
, vol.21
, Issue.10
, pp. 673-678
-
-
Selinski, S.1
Blaszkewicz, M.2
Lehmann, M.L.3
-
45
-
-
0036956985
-
Differences in N-acetylation genotypes between Caucasians and Black South Africans: Implications for cancer prevention
-
DOI 10.1016/S0361-090X(02)00010-7, PII S0361090X02000107
-
Loktionov A, Moore W, Spencer SP et al. Differences in N-acetylation genotypes between Caucasians and black South Africans: implications for cancer prevention. Cancer Detect. Prev. 26, 15-22 (2002). (Pubitemid 36087177)
-
(2002)
Cancer Detection and Prevention
, vol.26
, Issue.1
, pp. 15-22
-
-
Loktionov, A.1
Moore, W.2
Spencer, S.P.3
Vorster, H.4
Nell, T.5
O'Neill, I.K.6
Bingham, S.A.7
Cummings, J.H.8
-
46
-
-
42349100185
-
Worldwide distribution of NAT2 diversity: Implications for NAT2 evolutionary history
-
Sabbagh A, Langaney A, Darlu P, Gerard N, Krishnamoorthy R, Poloni ES. Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history. BMC Genet. 9, 21 (2008).
-
(2008)
BMC Genet.
, vol.9
, pp. 21
-
-
Sabbagh, A.1
Langaney, A.2
Darlu, P.3
Gerard, N.4
Krishnamoorthy, R.5
Poloni, E.S.6
-
47
-
-
79953743009
-
Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: A worldwide population survey
-
Sabbagh A, Darlu P, Crouau-Roy B, Poloni ES. Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: A worldwide population survey. PLoS ONE 6, e18507 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Sabbagh, A.1
Darlu, P.2
Crouau-Roy, B.3
Poloni, E.S.4
-
48
-
-
17644441355
-
Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity
-
Ohno M, Yamaguchi I, Yamamoto I et al. Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity. Int. J. Tuberc. Lung Dis. 4, 256-261 (2000). (Pubitemid 30151575)
-
(2000)
International Journal of Tuberculosis and Lung Disease
, vol.4
, Issue.3
, pp. 256-261
-
-
Ohno, M.1
Yamaguchi, J.2
Yamamoto, I.3
Fukuda, T.4
Yokota, S.5
Maekura, R.6
Ito, M.7
Yamamoto, Y.8
Ogura, T.9
Maeda, K.10
Komuta, K.11
Igarashi, T.12
Azuma, J.13
-
49
-
-
18244393817
-
Genotyping of the N-acetyltransferase 2 polymorphism in the prediction of adverse drug reactions to isoniazid in Japanese patients
-
Hiratsuka M, Kishikawa Y, Takekuma Y et al. Genotyping of the N-acetyltransferase 2 polymorphism in the prediction of adverse drug reactions to isoniazid in Japanese patients. Drug Metab. Pharmacokinet. 17, 357-362 (2002).
-
(2002)
Drug Metab. Pharmacokinet.
, vol.17
, pp. 357-362
-
-
Hiratsuka, M.1
Kishikawa, Y.2
Takekuma, Y.3
-
50
-
-
35348922264
-
Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
-
Cho HJ, Koh WJ, Ryu YJ et al. Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis. Tuberculosis 87, 551-556 (2007).
-
(2007)
Tuberculosis
, vol.87
, pp. 551-556
-
-
Cho, H.J.1
Koh, W.J.2
Ryu, Y.J.3
-
51
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich TM, Musunuru K, Smith AV et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 7071-7073 (2010).
-
(2010)
Nature
, vol.466
, pp. 7071-7073
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
|