Intratumoral injection of Propionibacterium acnes suppresses malignant melanoma by enhancing Th1 immune responses

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Tsuda, Kenshiro ^a   Yamanaka, Keiichi ^a   Linan, Wang ^a   Miyahara, Yoshihiro ^a   Akeda, Tomoko ^a   Nakanishi, Takehisa ^a   Kitagawa, Hiroshi ^a   Kakeda, Masato ^a   Kurokawa, Ichiro ^a   Shiku, Hiroshi ^a   Gabazza, Esteban C ^a   Mizutani, Hitoshi ^a  

^a MIE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; CORYNEBACTERIUM ACNES VACCINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 17; MACROPHAGE INFLAMMATORY PROTEIN 2; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE EXPRESSION; GRANULOMA; IMMUNE RESPONSE; IN VIVO STUDY; LYMPHOCYTIC INFILTRATION; MELANOMA; MONOCYTE; MOUSE; NONHUMAN; SPLEEN; TH1 CELL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR REGRESSION; ANIMAL; BIOSYNTHESIS; EXPERIMENTAL MELANOMA; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; INTRALESIONAL DRUG ADMINISTRATION; PATHOLOGY; PHYSIOLOGY; PROPIONIBACTERIUM ACNES;

ANIMALS; CYTOKINES; FLOW CYTOMETRY; INJECTIONS, INTRALESIONAL; MELANOMA, EXPERIMENTAL; MICE; PROPIONIBACTERIUM ACNES; RNA, MESSENGER; TH1 CELLS;

EID: 83755188136     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029020     Document Type: Article

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