Nonclinical safety profile of tolvaptan

Cardiovascular Drugs and Therapy

Volumn 25, Issue SUPPL. 1, 2011, Pages

  Oi, Akihide ^a   Morishita, Katsumi ^a   Awogi, Takumi ^a   Ozaki, Atsushi ^a   Umezato, Masanao ^a   Fujita, Shinji ^a   Hosoki, Eiji ^a   Morimoto, Hajime ^a   Ishiharada, Nobuya ^a   Ishiyama, Hironobu ^a   Uesugi, Tohru ^a   Miyatake, Masaya ^a   Senba, Tadashi ^a   Shiragiku, Toshiyuki ^a   Nakagiri, Naoto ^a   Ito, Norio ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Safety pharmacology; Tolvaptan; Toxicology

Indexed keywords

TOLVAPTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGENICITY; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DOG; DRUG EFFECT; DRUG SAFETY; EMBRYOTOXICITY; FEMALE; GENOTOXICITY; GROWTH RETARDATION; GUINEA PIG; IC 50; IMMUNOTOXICITY; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; POSTNATAL GROWTH; PRENATAL GROWTH; PRIORITY JOURNAL; RABBIT; RAT; REPRODUCTIVE TOXICITY; TERATOGENICITY; TOXICITY TESTING;

ANIMALS; BENZAZEPINES; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM; CHO CELLS; CRICETINAE; CRICETULUS; DIURETICS; DOGS; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; FEMORAL ARTERY; GUINEA PIGS; HEART RATE; ILEUM; MALE; MICE; MICE, INBRED ICR; MUSCLE CONTRACTION; PERIPHERAL NERVOUS SYSTEM; PREGNANCY; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASOPRESSIN; REGIONAL BLOOD FLOW; RESPIRATION; STOMACH;

EID: 83655212316     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-011-6356-y     Document Type: Article

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