Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines

Biometrics

Volumn 67, Issue 4, 2011, Pages 1271-1284

  Maity, Arnab ^a   Lin, Xihong ^b  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Garrote; Gene gene interaction; Kernel machine; Mixed models; Restricted maximum likelihood; Score test; Semiparametric regression

Indexed keywords

DEGREES OF FREEDOM (MECHANICS); GENE EXPRESSION; MAXIMUM LIKELIHOOD; SAMPLING;

GARROTE; GENE EFFECTS; GENE-GENE INTERACTION; KERNEL MACHINE; MIXED MODELING; NONNEGATIVE PARAMETERS; RESTRICTED MAXIMUM LIKELIHOOD; SCORE TEST; SEMI-PARAMETRIC REGRESSIONS; TESTING PROCEDURE;

DISEASES;

DETECTION METHOD; GENE EXPRESSION; GENETIC ANALYSIS; MACHINERY; NUMERICAL MODEL; PARAMETERIZATION; REGRESSION ANALYSIS; THEORETICAL STUDY;

MICHIGAN; UNITED STATES;

EID: 83655211690     PISSN: 0006341X     EISSN: 15410420     Source Type: Journal    
DOI: 10.1111/j.1541-0420.2011.01598.x     Document Type: Article

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