Automated determination of neutrophil VCS parameters in diagnosis and treatment efficacy of neonatal sepsis

Pediatric Research

Volumn 71, Issue 1, 2012, Pages 121-125

  Celik, Istemi H ^a   Demirel, Gamze ^a   Aksoy, Hatice T ^a   Erdeve, Omer ^a   Tuncer, Ece ^a   Biyikli, Zeynep ^b   Dilmen, Ugur ^a  

^a Zekai Tahir Burak Maternity Teaching Hospital   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOMATION; BLOOD SAMPLING; DIAGNOSTIC ACCURACY; FEMALE; GRAM NEGATIVE INFECTION; GRAM POSITIVE INFECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN NEUTROPHIL CONDUCTIVITY; MEAN NEUTROPHIL SCATTER; MEAN NEUTROPHIL VOLUME; NEUTROPHIL COUNT; NEWBORN; NEWBORN SEPSIS; PRIORITY JOURNAL;

FEMALE; GESTATIONAL AGE; HEMATOLOGIC TESTS; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; LEUKOCYTE COUNT; MALE; NEUTROPHILS; SENSITIVITY AND SPECIFICITY; SEPSIS; TREATMENT OUTCOME;

EID: 83655211559     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2011.16     Document Type: Article

References (19)

1. Osrin D, Vergnano S, Costello A. Serious bacterial infections in newborn infants in developing countries. Curr Opin Infect Dis 2004;17:217-24. (Pubitemid 38703850)
2. Gerdes JS. Diagnosis and management of bacterial infections in the neonate. Pediatr Clin North Am 2004;51:939-59, viii-ix. (Pubitemid 38962677)
3. Khassawneh M, Hayajneh WA, Kofahi H, Khader Y, Amarin Z, Daoud A. Diagnostic markers for neonatal sepsis: comparing C-reactive protein, interleukin-6 and immunoglobulin M. Scand J Immunol 2007;65:171-5. (Pubitemid 46174925)
4. Dilli D, Oguz SS, Dilmen U, Köker MY, Kizilgün M. Predictive values of neutrophil CD64 expression compared with interleukin-6 and C-reactive protein in early diagnosis of neonatal sepsis. J Clin Lab Anal 2010;24:363-70.
5. Celik IH, Demirel FG, Uras N, et al. What are the cut-off levels for IL-6 and CRP in neonatal sepsis? J Clin Lab Anal 2010;24:407-12.
6. Mathy KA, Koepke JA. The clinical usefulness of segmented vs. stab neutrophil criteria for differential leukocyte counts. Am J Clin Pathol 1974;61:947-58.
7. Wenz B, Gennis P, Canova C, Burns ER. The clinical utility of the leukocyte differential in emergency medicine. Am J Clin Pathol 1986;86:298-303. (Pubitemid 16023554)
8. Pierre RV. Peripheral blood film review. The demise of the eyecount leukocyte differential. Clin Lab Med 2002;22:279-97. (Pubitemid 34245402)
9. Richardson-Jones A. An automated hematology instrument for comprehensive WBC, RBC, and platelet analysis. Am Clin Lab 1990;9:18-22.
10. Krause JR. Automated differentials in the hematology laboratory. Am J Clin Pathol 1990;93(4 Suppl 1):S11-6. (Pubitemid 20108995)
11. Chaves F, Tierno B, Xu D. Quantitative determination of neutrophil VCS parameters by the Coulter automated hematology analyzer: new and reliable indicators for acute bacterial infection. Am J Clin Pathol 2005;124:440-4. (Pubitemid 41232931)
12. Mardi D, Fwity B, Lobmann R, Ambrosch A. Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 2010;32:410-8.
13. Raimondi F, Ferrara T, Capasso L, et al. Automated determination of neutrophil volume as screening test for late-onset sepsis in very low birth infants. Pediatr Infect Dis J 2010;29:288.
14. Chaves F, Tierno B, Xu D. Neutrophil volume distribution width: a new automated hematologic parameter for acute infection. Arch Pathol Lab Med 2006;130:378-80.
15. Lee JC, Ahern TP, Chaves FP, Quillen K. Utility of hematologic and volume, conductivity, and scatter parameters from umbilical cord blood in predicting chorioamnionitis. Int J Lab Hematol 2010; 32:351-9.
16. Koenig S, Quillen K. Using neutrophil and lymphocyte VCS indices in ambulatory pediatric patients presenting with fever. Int J Lab Hematol 2010;32:449-51.
17. Abe R, Oda S, Sadahiro T, et al. Gram-negative bacteremia induces greater magnitude of inflammatory response than Gram-positive bacteremia. Crit Care 2010;14:R27.
18. Webb SA, Kahler CM. Bench-to-bedside review: bacterial virulence and subversion of host defences. Crit Care 2008;12:234.
19. Haque KN. Definitions of bloodstream infection in the newborn. Pediatr Crit Care Med 2005;6(3 Suppl):S45-9. (Pubitemid 40724252)