Mitochondrial nitric oxide synthase participates in septic shock myocardial depression by nitric oxide overproduction and mitochondrial permeability transition pore opening

Shock

Volumn 37, Issue 1, 2012, Pages 110-115

  Xu, Ce ^a,b   Yi, Chenju ^c   Wang, Huiping ^b   Bruce, Iain C ^b   Xia, Qiang ^b  

^a SICHUAN UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

cecal ligation and puncture; mitochondrial nitric oxide synthase; mitochondrial permeability transition pore; Septic shock

Indexed keywords

7 NITROINDAZOLE; AMINOGUANIDINE; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOSOL; HEART MUSCLE; HEMODYNAMIC PARAMETERS; MALE; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; RAT; SEPTIC SHOCK; SURVIVAL RATE;

ANIMALS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDAZOLES; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MUSCLE PROTEINS; MYOCARDIUM; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, SEPTIC;

EID: 83655201322     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3182391831     Document Type: Article

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