Podoplanin expression during dysplasia-carcinoma sequence in the oral cavity

Tumor Biology

Volumn 33, Issue 1, 2012, Pages 183-194

  Inoue, Harumi ^a   Miyazaki, Yuji ^a   Kikuchi, Kentaro ^a   Yoshida, Noriaki ^a   Ide, Fumio ^a   Ohmori, Yoshihiro ^a   Tomomura, Akihito ^a   Sakashita, Hideaki ^a   Kusama, Kaoru ^a  

^a MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Dysplasia carcinoma sequence; Epidermal growth factor; Epithelial mesenchymal transition; Immunohistochemistry; Oral squamous cell carcinoma; Podoplanin

Indexed keywords

CANCER GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; PODOPLANIN; TUMOR GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MALIGNANT TRANSFORMATION; MOUTH CARCINOMA; NUCLEOTIDE SEQUENCE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA;

EID: 83655201210     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-011-0261-7     Document Type: Article

References (49)

1. SM Lippman WK Hong 2001 Molecular markers of the risk of oral cancer N Engl J Med 344 1323 6 11320393 10.1056/NEJM200104263441710 1:STN:280: DC%2BD3M3kvVamsw%3D%3D (Pubitemid 32372968)
2. L Mao WK Hong VA Papadimitrakopoulou 2004 Focus on head and neck cancer Cancer Cell 5 311 6 15093538 10.1016/S1535-6108(04)00090-X 1:CAS:528: DC%2BD2cXjvVaqtLY%3D (Pubitemid 38482067)
3. S Warnakulasuriya J Reibel J Bouquot E Dabelsteen 2008 Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement J Oral Pathol Med 37 127 33 18251935 10.1111/j.1600-0714. 2007.00584.x 1:STN:280:DC%2BD1c7ivVSktQ%3D%3D (Pubitemid 351178405)
4. K Kusama S Okutsu A Takeda T Himiya A Kojima Y Kidokoro, et al. 1996 p53 gene alterations and p53 protein in oral epithelial dysplasia and squamous cell carcinoma J Pathol 178 415 21 8691320 10.1002/(SICI)1096-9896(199604)178: 4<415::AID-PATH548>3.0.CO;2-1 1:CAS:528:DyaK28XjsVaqt7g%3D (Pubitemid 26145134)
5. E Meulmeester P ten Dijke 2010 Integration of transcriptional signals at the tumor cell invasive front Cell Cycle 9 2499 500 20647778 10.4161/cc.9.13.12278 1:CAS:528:DC%2BC3cXhsFCnt7rL
6. V Schacht MI Ramirez YK Hong S Hirakawa D Feng N Harvey, et al. 2003 T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema EMBO J 22 3546 56 12853470 10.1093/emboj/cdg342 1:CAS:528:DC%2BD3sXlsl2lur4%3D (Pubitemid 36898332)
7. S Breiteneder-Geleff K Matsui A Soleiman P Meraner H Poczewski R Kalt, et al. 1997 Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis Am J Pathol 151 1141 52 9327748 1:CAS:528:DyaK2sXmvFGmu7s%3D (Pubitemid 27424324)
8. A Wetterwald W Hoffstetter MG Cecchini B Lanske C Wagner H Fleisch, et al. 1996 Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes Bone 18 125 32 8833206 10.1016/8756-3282(95) 00457-2 1:CAS:528:DyaK28XisVGjs7c%3D (Pubitemid 26092592)
9. Y Kato MK Kaneko A Kunita H Ito A Kameyama S Ogasawara, et al. 2008 Molecular analysis of the pathophysiological binding of the platelet aggregation-inducing factor podoplanin to the C-type lectin-like receptor CLEC-2 Cancer Sci 99 54 61 17944973 1:CAS:528:DC%2BD1cXnsFWmsQ%3D%3D (Pubitemid 350239031)
10. MC Williams Y Cao A Hinds AK Rishi A Wetterwald 1996 T1 alpha protein is developmentally regulated and expressed by alveolar type I cells, choroid plexus, and ciliary epithelia of adult rats Am J Respir Cell Mol Biol 14 577 85 8652186 1:CAS:528:DyaK28XjvVGgt7Y%3D (Pubitemid 126442949)
11. E Martín-Villar FG Scholl C Gamallo MM Yurrita M Muñoz-Guerra J Cruces, et al. 2005 Characterization of human PA2.26 antigen (T1α-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas Int J Cancer 113 899 910 15515019 10.1002/ijc.20656 (Pubitemid 40096869)
12. Oku Y, Tanaka A, González-Alva P, Sakashita H, Kusama K. Podoplanin expression in human pleomorphic adenomas. In: Varma AK, Qiu WL, editors. Oral Oncology. Shanghai: Ocean Papers & Printers; 2008. p. 251-3.
13. Y Miyazaki E Okamoto P González-Alva J Hayashi T Ishige K Kikuchi, et al. 2009 The significance of podoplanin expression in human inflamed gingiva J Oral Sci 51 283 7 19550098 10.2334/josnusd.51.283
14. P Yuan S Temam A El-Naggar X Zhou DD Liu JJ Lee, et al. 2006 Overexpression of podoplanin in oral cancer and its association with poor clinical outcome Cancer 107 563 9 16804930 10.1002/cncr.22061 1:CAS:528:DC%2BD28Xot1aksLc%3D (Pubitemid 44107217)
15. M Raica AM Cimpean D Ribatti 2008 The role of podoplanin in tumor progression and metastasis Anticancer Res 28 2997 3006 19031946
16. H Kawaguchi AK El-Naggar V Papadimitrakopoulou H Ren YH Fan L Feng, et al. 2008 Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy J Clin Oncol 26 354 60 18202409 10.1200/JCO.2007.13.4072 (Pubitemid 351171684)
17. V Schacht SS Dadras LA Johnson DG Jackson YK Hong M Detmar 2005 Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors Am J Pathol 166 913 21 15743802 10.1016/S0002-9440(10)62311-5 1:CAS:528: DC%2BD2MXivVOmsbk%3D (Pubitemid 40315647)
18. BM Erovic C Neuchrist S Kandutsch M Woegerbauer J Pammer 2003 CD9 expression on lymphatic vessels in head and neck mucosa Mod Pathol 16 1028 34 14559986 10.1097/01.MP.0000089777.58000.B2 (Pubitemid 37280819)
19. RC Ji K Kurihara S Kato 2006 Lymphatic vascular endothelial hyaluronan receptor (LYVE)-1- and CCL21-positive lymphatic compartments in the diabetic thymus Anat Sci Int 81 201 9 17176958 10.1111/j.1447-073X.2006.00145.x (Pubitemid 44650996)
20. E Sinzelle JP Duong Van Huyen S Breiteneder-Geleff E Braunberger A Deloche D Kerjaschki, et al. 2000 Intrapericardial lymphangioma with podoplanin immunohistochemical characterization of lymphatic endothelial cells Histopathology 37 93 4 10931742 10.1046/j.1365-2559.2000.00955-8.x 1:STN:280:DC%2BD3cvgsVWquw%3D%3D (Pubitemid 30496746)
21. S Breiteneder-Geleff A Soleiman H Kowalski R Horvat G Amann E Kriehuber, et al. 1999 Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium Am J Pathol 154 385 94 10027397 10.1016/S0002-9440(10)65285-6 1:STN:280:DyaK1M7kvFKnsQ%3D%3D (Pubitemid 29094089)
22. S Oe K Hasegawa S Nagase R Kato Y Torii Y Udagawa 2010 Expression of podoplanin in epithelial ovarian carcinomas and its potential as a marker for clear cell adenocarcinoma Int J Gynecol Pathol 29 405 10 20736762 10.1097/PGP.0b013e3181d3261e
23. SB Sonne AS Herlihy CE Hoei-Hansen JE Nielsen K Almstrup NE Skakkebaek, et al. 2006 Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours Virchows Arch 449 200 6 16736189 10.1007/s00428-006-0223-4 1:CAS:528: DC%2BD28XpvFamtrk%3D
24. DM Padgett HP Cathro MR Wick SE Mills 2008 Podoplanin is a better immunohistochemical marker for sarcomatoid mesothelioma than calretinin Am J Surg Pathol 32 123 7 18162779 10.1097/PAS.0b013e31814faacf
25. K Mishima Y Kato MK Kaneko R Nishikawa T Hirose M Matsutani 2006 Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression Acta Neuropathol 111 483 8 16596424 10.1007/s00401-006-0063-y 1:CAS:528:DC%2BD28XktFSqt78%3D
26. J Shibahara T Kashima Y Kikuchi A Kunita M Fukayama 2006 Podoplanin is expressed in subsets of tumors of the central nervous system Virchows Arch 448 493 9 16411134 10.1007/s00428-005-0133-x 1:CAS:528:DC%2BD28XjtFamsL8%3D
27. M Durchdewald J Guinea-Viniegra D Haag A Riehl P Lichter M Hahn, et al. 2008 Podoplanin is a novel fos target gene in skin carcinogenesis Cancer Res 68 6877 83 18757399 10.1158/0008-5472.CAN-08-0299 1:CAS:528:DC%2BD1cXhtVCrs77P
28. Y Shimada G Ishii K Nagai N Atsumi S Fujii A Yamada, et al. 2009 Expression of podoplanin, CD44, and p63 in squamous cell carcinoma of the lung Cancer Sci 100 2054 9 19681903 10.1111/j.1349-7006.2009.01295.x 1:CAS:528:DC%2BD1MXhsVSktLbO
29. KL Dumoff CS Chu EE Harris D Holtz X Xu PJ Zhang, et al. 2006 Low podoplanin expression in pretreatment biopsy material predicts poor prognosis in advanced-stage squamous cell carcinoma of the uterine cervix treated by primary radiation Mod Pathol 19 708 16 16528371 10.1038/modpathol.3800580 1:CAS:528:DC%2BD28Xjs1agur8%3D
30. WY Chuang CJ Yeh YC Wu YK Chao YH Liu CK Tseng, et al. 2009 Tumor cell expression of podoplanin correlates with nodal metastasis in esophageal squamous cell carcinoma Histol Histopathol 24 1021 7 19554509 1:CAS:528: DC%2BD1MXhtVahsr3E
31. N Rahadiani J Ikeda T Makino T Tian Y Qiu S Mamat, et al. 2010 Tumorigenic role of podoplanin in esophageal squamous-cell carcinoma Ann Surg Oncol 17 1311 23 20066519 10.1245/s10434-009-0895-5
32. JP Rodrigo D García-Carracedo MV González G Mancebo MF Fresno J García-Pedrero 2010 Podoplanin expression in the development and progression of laryngeal squamous cell carcinomas Mol Cancer 9 48 20196862
33. A Wicki F Lehembre N Wick B Hantusch D Kerjaschki G Christofori 2006 Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton Cancer Cell 9 261 72 16616332 10.1016/j.ccr.2006.03.010 1:CAS:528:DC%2BD28XjvFeiurw%3D
34. A Wicki G Christofori 2007 The potential role of podoplanin in tumour invasion Br J Cancer 96 1 5 17179989 10.1038/sj.bjc.6603518 1:CAS:528: DC%2BD2sXis1Kgtg%3D%3D (Pubitemid 46094630)
35. P González-Alva A Tanaka Y Oku Y Miyazaki E Okamoto M Fujinami, et al. 2010 Enhanced expression of podoplanin in ameloblastomas J Oral Pathol Med 39 103 9 19691459 10.1111/j.1600-0714.2009.00818.x
36. E Okamoto K Kikuchi Y Miyazaki P González-Alva Y Oku A Tanaka, et al. 2010 Significance of podoplanin expression in keratocystic odontogenic tumor J Oral Pathol Med 39 110 4 19925582 10.1111/j.1600-0714.2009.00851.x 1:CAS:528:DC%2BC3cXitVWjsLg%3D
37. Y Miyazaki K Kikuchi P González-Alva H Inoue Y Noguchi H Tsuchiya, et al. 2010 Association of butyric acid produced by periodontopathic bacteria with progression of oral cancer J Cancer Sci Ther. 2 026 32 1:CAS:528: DC%2BC3cXmtF2msb8%3D
38. c-Src activation in human colon carcinoma J Clin Invest 83 2025 33 2498394 10.1172/JCI114113 1:CAS:528:DyaL1MXksFGjsrw%3D (Pubitemid 19148875)
39. c-Src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas Cancer Res 43 1696 702 6403227 1:CAS:528:DyaL3sXhslOjtL4%3D (Pubitemid 13122574)
40. AE Ottenhoff-Kalff G Rijksen EA van Beurden A Hennipman AA Michels GE Staal 1992 Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-Src oncogene product Cancer Res 52 4773 8 1380891 1:CAS:528:DyaK38XmsV2hur4%3D
41. S Xi Q Zhang KF Dyer EC Lerner TE Smithgall WE Gooding, et al. 2003 Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck J Biol Chem 278 31574 83 12771142 10.1074/jbc.M303499200 1:CAS:528:DC%2BD3sXmsVOntrY%3D (Pubitemid 37048335)
42. Cas Nat Genet 19 361 5 9697697 10.1038/1246 1:CAS:528:DyaK1cXlt1Cisrw%3D (Pubitemid 28357908)
43. GS Goldberg DB Alexander P Pellicena ZY Zhang H Tsuda WT Miller 2003 Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells J Biol Chem 278 46533 40 12972425 10.1074/jbc.M307526200 1:CAS:528: DC%2BD3sXovFKlu74%3D (Pubitemid 37452226)
44. Y Shen C-S Chen H Ichikawa GS Goldberg 2009 Src induces podoplanin expression to promote cell migration J Biol Chem 285 9649 56 10.1074/jbc.M109.047696
45. Barnes L, Eveson JW, Reichart P, Sidransky Ds. World health organization classification of tumours. Pathology and genetics of head and neck tumours. Place: IARC; 2005. p.177-81.
46. Barnes L, Eveson JW, Reichart P, Sidransky Ds. World health organization classification of tumours. Pathology and genetics of head and neck tumours. Place: IARC; 2005. p.168-75.
47. A Funayama J Cheng S Maruyama M Yamazaki T Kobayashi M Syafriadi, et al. 2011 Enhanced expression of podoplanin in oral carcinomas in situ and squamous cell carcinomas Pathobiology 78 171 80 21613804 10.1159/000324926 1:CAS:528:DC%2BC3MXnvF2lsrc%3D
48. M Kreppel M Scheer U Drebber L Ritter JE Zöller 2010 Impact of podoplanin expression in oral squamous cell carcinoma: clinical and histopathologic correlations Virchows Arch 456 473 82 20393745 10.1007/s00428-010-0915-7 1:CAS:528:DC%2BC3cXlsFKlu78%3D
49. H Nozawa G Howell S Suzuki Q Zhang Y Qi J Klein-Seetharaman, et al. 2008 Combined inhibition of PLCγ-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion Clin Cancer Res 14 4336 44 18594017 10.1158/1078-0432.CCR-07-4857 1:CAS:528: DC%2BD1cXnvFyksL0%3D