Flow sensing of single cell by graphene transistor in a microfluidic channel

Nano Letters

Volumn 11, Issue 12, 2011, Pages 5240-5246

  Ang, Priscilla Kailian ^a,b   Li, Ang ^c,d   Jaiswal, Manu ^a   Wang, Yu ^a   Hou, Han Wei ^c,d   Thong, John T L ^d   Lim, Chwee Teck ^c,d,e   Loh, Kian Ping ^a  

^a National University of Singapore   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

cell surface charge density; field effect transistor; Graphene; infectious disease; microfluidics; single cell detection

Indexed keywords

CAPACITIVELY COUPLED; CELL SURFACES; CYTOMETRY; DISEASE STATE; DWELL TIME; FLOW SENSING; GRAPHENE TRANSISTORS; HIGHLY SENSITIVE; INFECTIOUS DISEASE; LOCAL DIELECTRICS; MICROFLUIDIC CHANNEL; MICROFLUIDIC FLOW; RED BLOOD CELL; SINGLE CELLS; SINGLE-CELL DETECTION; SINGLE-CELL LEVEL;

BLOOD; CELL MEMBRANES; ELECTRONIC PROPERTIES; FIELD EFFECT TRANSISTORS; FLOW CYTOMETRY; GRAPHENE;

MICROFLUIDICS;

EID: 83655192479     PISSN: 15306984     EISSN: 15306992     Source Type: Journal    
DOI: 10.1021/nl202579k     Document Type: Article

References (22)

1. Bhagat, A. A.; Bow, H.; Hou, H. W.; Tan, S. J.; Han, J.; Lim, C. T. Med. Biol. Eng. Comput. 2010, 48, 999-1014
2. Hou, H. W.; Bhagat, A. A.; Chong, A. G.; Mao, P.; Tan, K. S.; Han, J.; Lim, C. T. Lab Chip 2010, 10, 2605-2613
3. Wang, Z.; El-Ali, J.; Engelund, M.; Gotsaed, T.; Perch-Nielsen, I. R.; Mogensen, K. B.; Snakenborg, D.; Kutter, J. P.; Wolff, A. Lab Chip 2004, 4, 372-377
4. Kim, M.; Hwang, D. J.; Jeon, H.; Hiromatsu, K.; Grigoropoulos, C. P. Lab Chip 2009, 9, 311-318
5. Patolsky, F.; Zheng, G.; Hayden, O.; Lakadamyali, M.; Zhuang, X.; Lieber, C. M. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 14017-22
6. Castro Neto, A. H.; Guinea, F.; Peres, N. M. R.; Novoselov, K. S.; Geim, A. K. Rev. Mod. Phys. 2009, 81, 109
7. Dong, X.; Shi, Y.; Huang, W.; Chen, P.; Li, L. J. Adv. Mater. 2010, 22, 1649-1653
8. Fedosov, D. A.; Caswell, B.; Karniadakis, G. E. Biophys. J. 2011, 100, 2084-2093
9. Fedosov, D. A.; Caswell, B.; Suresh, S.; Karniadakis, G. E. Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 35-39
10. de Koning-Ward, T. F.; Gilson, P. R.; Boddey, J. A.; Rug, M.; Smith, B. J.; Papenfuss, A. T.; Sanders, P. R.; Lundie, R. J.; Maier, A. G.; Cowman, A. F.; Crabb, B. S. Nature 2009, 459, 945-949
11. Aikawa, M.; Kamanura, K.; Shiraishi, S.; Matsumoto, Y.; Arwati, H.; Torii, M.; Ito, Y.; Takeuchi, T.; Tandler, B. Exp. Parasitol. 1996, 84, 339-343
12. Li, A.; Mansoor, A. H.; Tan, K. S.; Lim, C. T. J. Microbiol. Methods 2006, 66, 434-439
13. McCormick, C. J.; Newbold, C. I.; Berendt, A. R. Blood 2000, 96, 327-333
14. Lim, C. T.; Li, A. Theor. Appl. Mech. Lett. 2011, 1, 014000
15. Loh, K. P.; Bao, Q. L.; Ang, P. K.; Yang, J. X. J. Mater. Chem. 2010, 20, 2277-2289
16. Cole, D. J.; Payne, M. C.; Ciacchi, L. C. Phys. Chem. Chem. Phys. 2009, 11, 11395-11399
17. Kim, J.; Cote, L. J.; Kim, F.; Huang, J. J. Am. Chem. Soc. 2010, 132, 260-267
18. Ang, P. K.; Jaiswal, M.; Lim, C. H.; Wang, Y.; Sankaran, J.; Li, A.; Lim, C. T.; Wohland, T.; Barbaros, O.; Loh, K. P. ACS Nano 2010, 4, 7387-7394
19. Adam, S.; Hwang, E. H.; Galitski, V. M.; Das Sarma, S. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 18392-18397
20. Das Sarma, S.; Adam, S.; Hwang, E. H.; Rossi, E. Rev. Mod. Phys. 2011, 83, 407
21. Bianco, B.; Giordano, S. Int. J. Circuit Theory Appl. 2003, 31, 199-218
22. Cooke, B. M.; Berendt, A. R.; Craig, A. G.; MacGregor, J.; Newbold, C. I.; Nash, G. B. Br. J. Haematol. 1994, 87, 162-170