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Volumn 14, Issue 1, 2012, Pages 67-76

Effect of initial combination therapy with sitagliptin and metformin on β-cell function in patients with type 2 diabetes

Author keywords

DPP IV inhibitor; Metformin; Type 2 diabetes; cell

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN; METFORMIN; PLACEBO; SITAGLIPTIN;

EID: 83655163721     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2011.01492.x     Document Type: Article
Times cited : (42)

References (31)
  • 1
    • 0036615275 scopus 로고    scopus 로고
    • The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes.
    • Bergman RN, Finegood DT, Kahn SE. The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes. Eur J Clin Invest 2002; 32(Suppl. 3): 35-45.
    • (2002) Eur J Clin Invest , vol.32 , Issue.SUPPL. 3 , pp. 35-45
    • Bergman, R.N.1    Finegood, D.T.2    Kahn, S.E.3
  • 2
    • 0028817815 scopus 로고
    • UK prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease.
    • UK Prospective Diabetes Study Group.
    • UK Prospective Diabetes Study Group. UK prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. Diabetes 1995; 44: 1249-1258.
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 3
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
    • Kahn SE, Haffner SM, Heise MA et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006; 355: 2427-2443.
    • (2006) N Engl J Med , vol.355 , pp. 2427-2443
    • Kahn, S.E.1    Haffner, S.M.2    Heise, M.A.3
  • 4
    • 33745302884 scopus 로고    scopus 로고
    • The natural course of beta-cell function in nondiabetic and diabetic individuals: the Insulin Resistance Atherosclerosis Study.
    • Festa A, Williams K, D'Agostino R Jr, Wagenknecht LE, Haffner SM. The natural course of beta-cell function in nondiabetic and diabetic individuals: the Insulin Resistance Atherosclerosis Study. Diabetes 2006; 55: 1114-1120.
    • (2006) Diabetes , vol.55 , pp. 1114-1120
    • Festa, A.1    Williams, K.2    D'Agostino Jr., R.3    Wagenknecht, L.E.4    Haffner, S.M.5
  • 5
    • 18644376240 scopus 로고    scopus 로고
    • Type 2 diabetes, insulin secretion and beta-cell mass.
    • Ahren B. Type 2 diabetes, insulin secretion and beta-cell mass. Curr Mol Med 2005; 5: 275-286.
    • (2005) Curr Mol Med , vol.5 , pp. 275-286
    • Ahren, B.1
  • 6
    • 12744263199 scopus 로고    scopus 로고
    • Islet adaptation to insulin resistance: mechanisms and implications for intervention.
    • Ahren B, Pacini G. Islet adaptation to insulin resistance: mechanisms and implications for intervention. Diabetes Obes Metab 2005; 7: 2-8.
    • (2005) Diabetes Obes Metab , vol.7 , pp. 2-8
    • Ahren, B.1    Pacini, G.2
  • 7
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones.
    • Drucker DJ. The biology of incretin hormones. Cell Metab 2006; 3: 153-165.
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 8
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006; 368: 1696-1705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 9
    • 39749169723 scopus 로고    scopus 로고
    • Sitagliptin, a DPP-4 inhibitor for the treatment of patients with type 2 diabetes: a review of recent clinical trials.
    • Karasik A, Aschner P, Katzeff H, Davies MJ, Stein PP. Sitagliptin, a DPP-4 inhibitor for the treatment of patients with type 2 diabetes: a review of recent clinical trials. Curr Med Res Opin 2008; 24: 489-496.
    • (2008) Curr Med Res Opin , vol.24 , pp. 489-496
    • Karasik, A.1    Aschner, P.2    Katzeff, H.3    Davies, M.J.4    Stein, P.P.5
  • 10
    • 77949285419 scopus 로고    scopus 로고
    • Sitagliptin: a review of its use in the management of type 2 diabetes mellitus.
    • Dhillon S. Sitagliptin: a review of its use in the management of type 2 diabetes mellitus. Drugs 2010; 70: 489-512.
    • (2010) Drugs , vol.70 , pp. 489-512
    • Dhillon, S.1
  • 11
    • 78449274342 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1.
    • Migoya EM, Bergeron R, Miller JL et al. Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1. Clin Pharmacol Ther 2010; 88: 801-808.
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 801-808
    • Migoya, E.M.1    Bergeron, R.2    Miller, J.L.3
  • 12
    • 0035097211 scopus 로고    scopus 로고
    • Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects.
    • Mannucci E, Ognibene A, Cremasco F et al. Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects. Diabetes Care 2001; 24: 489-494.
    • (2001) Diabetes Care , vol.24 , pp. 489-494
    • Mannucci, E.1    Ognibene, A.2    Cremasco, F.3
  • 13
    • 79953791624 scopus 로고    scopus 로고
    • Sitagliptin and metformin increase active GLP-1 by complementary mechanisms in treatment-naive patients with type 2 diabetes (abstract).
    • Migoya E, Miller J, Luo WL et al. Sitagliptin and metformin increase active GLP-1 by complementary mechanisms in treatment-naive patients with type 2 diabetes (abstract). Diabetes 2010; 59(Suppl. 1): A156.
    • (2010) Diabetes , vol.59 , Issue.SUPPL. 1
    • Migoya, E.1    Miller, J.2    Luo, W.L.3
  • 14
    • 34547660561 scopus 로고    scopus 로고
    • Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes.
    • Goldstein BJ, Feinglos MN, Lunceford JK, Johnson J, Williams-Herman DE. Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes. Diabetes Care 2007; 30: 1979-1987.
    • (2007) Diabetes Care , vol.30 , pp. 1979-1987
    • Goldstein, B.J.1    Feinglos, M.N.2    Lunceford, J.K.3    Johnson, J.4    Williams-Herman, D.E.5
  • 15
    • 65449135058 scopus 로고    scopus 로고
    • Efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes: a 54-week study.
    • Williams-Herman D, Johnson J, Teng R et al. Efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes: a 54-week study. Curr Med Res Opin 2009; 25: 569-583.
    • (2009) Curr Med Res Opin , vol.25 , pp. 569-583
    • Williams-Herman, D.1    Johnson, J.2    Teng, R.3
  • 16
    • 77952083721 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin and metformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes.
    • Williams-Herman D, Johnson J, Teng R et al. Efficacy and safety of sitagliptin and metformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes. Diabetes Obes Metab 2010; 12: 442-451.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 442-451
    • Williams-Herman, D.1    Johnson, J.2    Teng, R.3
  • 17
    • 0035149713 scopus 로고    scopus 로고
    • Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.
    • Breda E, Cavaghan MK, Toffolo G, Polonsky KS, Cobelli C. Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity. Diabetes 2001; 50: 150-158.
    • (2001) Diabetes , vol.50 , pp. 150-158
    • Breda, E.1    Cavaghan, M.K.2    Toffolo, G.3    Polonsky, K.S.4    Cobelli, C.5
  • 18
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.
    • Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999; 22: 1462-1470.
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.A.2
  • 19
    • 0031940813 scopus 로고    scopus 로고
    • SAAM II: simulation, analysis, and modeling software for tracer and pharmacokinetic studies.
    • Barrett PH, Bell BM, Cobelli C et al. SAAM II: simulation, analysis, and modeling software for tracer and pharmacokinetic studies. Metabolism 1998; 47: 484-492.
    • (1998) Metabolism , vol.47 , pp. 484-492
    • Barrett, P.H.1    Bell, B.M.2    Cobelli, C.3
  • 20
    • 0000270234 scopus 로고
    • The efficiency of some nonparametric competitors of the t-test.
    • Hodges JL, Lehmann EL. The efficiency of some nonparametric competitors of the t-test. Ann Math Statist 1956; 27: 324-335.
    • (1956) Ann Math Statist , vol.27 , pp. 324-335
    • Hodges, J.L.1    Lehmann, E.L.2
  • 21
    • 0002331280 scopus 로고
    • The future of data analysis.
    • Tukey JW. The future of data analysis. Ann Math Statist 1962; 33: 1-67.
    • (1962) Ann Math Statist , vol.33 , pp. 1-67
    • Tukey, J.W.1
  • 22
    • 33846005796 scopus 로고    scopus 로고
    • Incretin effect potentiates beta-cell responsivity to glucose as well as to its rate of change: OGTT and matched intravenous study.
    • Campioni M, Toffolo G, Shuster LT, Service FJ, Rizza RA, Cobelli C. Incretin effect potentiates beta-cell responsivity to glucose as well as to its rate of change: OGTT and matched intravenous study. Am J Physiol Endocrinol Metab 2007; 292: E54-E60.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Campioni, M.1    Toffolo, G.2    Shuster, L.T.3    Service, F.J.4    Rizza, R.A.5    Cobelli, C.6
  • 23
    • 55449096196 scopus 로고    scopus 로고
    • Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on beta-cell function in patients with type 2 diabetes: a model-based approach.
    • Xu L, Dalla Man C, Charbonnel B et al. Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on beta-cell function in patients with type 2 diabetes: a model-based approach. Diabetes Obes Metab 2008; 10: 1212-1220.
    • (2008) Diabetes Obes Metab , vol.10 , pp. 1212-1220
    • Xu, L.1    Dalla Man, C.2    Charbonnel, B.3
  • 24
    • 33846796143 scopus 로고    scopus 로고
    • Effect of adding sitagliptin, a dipeptidyl peptidase-4 inhibitor, to metformin on 24-h glycaemic control and beta-cell function in patients with type 2 diabetes.
    • Brazg R, Xu L, Dalla Man C, Cobelli C, Thomas K, Stein PP. Effect of adding sitagliptin, a dipeptidyl peptidase-4 inhibitor, to metformin on 24-h glycaemic control and beta-cell function in patients with type 2 diabetes. Diabetes Obes Metab 2007; 9: 186-193.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 186-193
    • Brazg, R.1    Xu, L.2    Dalla Man, C.3    Cobelli, C.4    Thomas, K.5    Stein, P.P.6
  • 25
    • 34247269160 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin.
    • Herman GA, Stein PP, Thornberry NA, Wagner JA. Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin. Clin Pharmacol Ther 2007; 81: 761-767.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 761-767
    • Herman, G.A.1    Stein, P.P.2    Thornberry, N.A.3    Wagner, J.A.4
  • 26
    • 0034853485 scopus 로고    scopus 로고
    • Clinical review 135: the importance of beta-cell failure in the development and progression of type 2 diabetes.
    • Kahn SE. Clinical review 135: the importance of beta-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 2001; 86: 4047-4058.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4047-4058
    • Kahn, S.E.1
  • 27
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes.
    • Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003; 46: 3-19.
    • (2003) Diabetologia , vol.46 , pp. 3-19
    • Kahn, S.E.1
  • 28
    • 23044487247 scopus 로고    scopus 로고
    • Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year.
    • Ahren B, Pacini G, Foley JE, Schweizer A. Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year. Diabetes Care 2005; 28: 1936-1940.
    • (2005) Diabetes Care , vol.28 , pp. 1936-1940
    • Ahren, B.1    Pacini, G.2    Foley, J.E.3    Schweizer, A.4
  • 29
    • 0029582922 scopus 로고
    • Glucose toxicity: the implications of hyperglycemia in the pathophysiology of diabetes mellitus.
    • Rossetti L. Glucose toxicity: the implications of hyperglycemia in the pathophysiology of diabetes mellitus. Clin Invest Med 1995; 18: 255-260.
    • (1995) Clin Invest Med , vol.18 , pp. 255-260
    • Rossetti, L.1
  • 30
    • 38149137991 scopus 로고    scopus 로고
    • Characterization of the influence of vildagliptin on model-assessed β-cell function in patients with type 2 diabetes and mild hyperglycemia.
    • Mari A, Scherbaum WA, Nilsson PM et al. Characterization of the influence of vildagliptin on model-assessed β-cell function in patients with type 2 diabetes and mild hyperglycemia. J Clin Endocrinol Metab 2008; 93: 103-109.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 103-109
    • Mari, A.1    Scherbaum, W.A.2    Nilsson, P.M.3
  • 31
    • 77949387699 scopus 로고    scopus 로고
    • Safety and efficacy of treatment with sitagliptin or glipizide in patients with type 2 diabetes inadequately controlled on metformin: a 2-year study.
    • Seck T, Nauck MA, Sheng D et al. Safety and efficacy of treatment with sitagliptin or glipizide in patients with type 2 diabetes inadequately controlled on metformin: a 2-year study. Int J Clin Pract 2010; 64: 562-576.
    • (2010) Int J Clin Pract , vol.64 , pp. 562-576
    • Seck, T.1    Nauck, M.A.2    Sheng, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.