Cyclooxygenase-2 -765G>C polymorphism is associated with C-reactive protein levels in resistant smokers but not in chronic obstructive pulmonary disease patients

Respiratory Physiology and Neurobiology

Volumn 180, Issue 1, 2012, Pages 119-125

  López Campos, José Luis ^a,b   Montes Worboys, Ana ^b   Calero, Carmen ^a   Márquez Martin, Eduardo ^a   Cejudo, Pilar ^a   Ortega, Francisco ^a   Arellano, Elena ^b  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^b Instituto de Biomedicina de Sevilla   (Spain)

Author keywords

Biomarkers; Chronic obstructive pulmonary disease; Cyclooxygenase 2; Genetics; Inflammation; Polymorphism; Smoking

Indexed keywords

C REACTIVE PROTEIN; CORTICOSTEROID; CYCLOOXYGENASE 2; FLUTICASONE; GENOMIC DNA; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; SERUM AMYLOID A; STEROID; TIOTROPIUM BROMIDE;

ADULT; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING;

AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CYCLOOXYGENASE 2; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERUM AMYLOID A PROTEIN; SMOKING;

EID: 83555179080     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2011.11.001     Document Type: Article

References (38)

1. Abdullah L., Ait-Ghezala G., Crawford F., Crowell T.A., Barker W.W., Duara R., Mullan M. The cyclooxygenase 2 -765C promoter allele is a protective factor for Alzheimer's disease. Neurosci. Lett. 2006, 395:240-243.
2. Agustí A. Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should). Proc. Am. Thorac. Soc. 2007, 4:522-525.
3. Antonescu-Turcu A.L., Tomic R. C-reactive protein and copeptin: prognostic predictors in chronic obstructive pulmonary disease exacerbations. Curr. Opin. Pulm. Med. 2009, 15:120-125.
4. Barnes P.J., Celli B.R. Systemic manifestations and comorbidities of COPD. Eur. Respir. J. 2009, 33:1165-1185.
5. Barnes P.J., Shapiro S.D., Pauwels R.A. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur. Respir. J. 2003, 22:672-688.
6. Benson M.D., Cohen A.S. Serum amyloid A protein in amyloidosis, rheumatic, and neoplastic diseases. Arthritis. Rheum. 1979, 22:36-42.
7. Bernard P.B., Witter C.T. Homogenous amplification and variant detection by fluorescent hybridization probes by fluorescent hybridization probes. Clin. Chem. 2000, 46:147-148.
8. Bozinovski S., Hutchinson A., Thompson M., Macgregor L., Black J., Giannakis E., Karlsson A.S., Silvestrini R., Smallwood D., Vlahos R., Irving L.B., Anderson G.P. Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2008, 177:269-278.
9. Chan S.C., Shum D.K., Tipoe G.L., Mak J.C., Leung E.T., Ip M.S. Upregulation of ICAM-1 expression in bronchial epithelial cells by airway secretions in bronchiectasis. Respir. Med. 2008, 102:287-298.
10. Charlson M., Szatrowski T.P., Peterson J., Gold J. Validation of a combined comorbidity index. J. Clin. Epidemiol. 1994, 47:1245-1251.
11. Chen Y., Chen P. Expressions of cyclooxygenase-2 and matrix metalloproteinase-2 and airflow obstruction in patients with chronic obstructive pulmonary disease. Zhonghua Jie He He Hu Xi Za Zhi 2005, 28:324-327.
12. Cipollone F., Toniato E., Martinotti S., Fazia M., Iezzi A., Cuccurullo C., Pini B., Ursi S., Vitullo G., Averna M., Arca M., Montali A., Campagna F., Ucchino S., Spigonardo F., Taddei S., Virdis A., Ciabattoni G., Notarbartolo A., Cuccurullo F., Mezzetti A., Identification of New Elements of Plaque Stability (INES) Study Group Identification of New Elements of Plaque Stability (INES) Study Group. A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke. J. Am. Med. Assoc. 2004, 291:2221-2228.
13. Dahl M., Vestbo J., Lange P., Bojesen S.E., Tybjaerg-Hansen A., Nordestgaard B.G. C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2007, 175:250-255.
14. Dahl M., Vestbo J., Zacho J., Lange P., Tybjærg-Hansen A., Nordestgaard B.G. C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach. Thorax 2011, 66:197-204.
15. de Torres J.P., Cordoba-Lanus E., Lopez-Aguilar C., Muros de Fuentes M., Montejo de Garcini A., Aguirre-Jaime A., Celli B.R., Casanova C. C-reactive protein levels and clinically important predictive outcomes in stable COPD patients. Eur. Respir. J. 2006, 27:902-907.
16. Emerging Risk Factors Collaboration, Kaptoge S., Di Angelantonio E., Lowe G., Pepys M.B., Thompson S.G., Collins R., Danesh J. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 2010, 375:132-140.
17. Fletcher C.M., Elmes P.C., Fairbairn A.S., Wood C.H. The significance of respiratory symptoms and the diagnosis of chronic bronchitis in a working population. Br. Med. J. 1959, 5147:257-266.
18. Gabay C., Kushner I. Acute-phase proteins and other systemic responses to inflammation. N. Engl. J. Med. 1999, 340:448-454.
19. Gamble E., Grootendorst D.C., Hattotuwa K., O'Shaughnessy T., Ram F.S., Qiu Y., Zhu J., Vignola A.M., Kroegel C., Morell F., Pavord I.D., Rabe K.F., Jeffery P.K., Barnes N.C. Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis. Eur. Respir. J. 2007, 30:467-471.
20. Garcia-Rio F., Miravitlles M., Soriano J.B., Muñoz L., Duran-Tauleria E., Sánchez G., Sobradillo V., Ancochea J., EPI-SCAN Steering Committee Systemic inflammation in chronic obstructive pulmonary disease: a population-based study. Respir. Res. 2010, 11:63.
21. Hogg J.C., Chu F., Utokaparch S., Woods R., Elliott W.M., Buzatu L., Cherniack R.M., Rogers R.M., Sciurba F.C., Coxson H.O., Paré P.D. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N. Engl. J. Med. 2004, 350:2645-2653.
22. Koutsokera A., Kiropoulos T.S., Nikoulis D.J., Daniil Z.D., Tsolaki V., Tanou K., Papaioannou A.I., Germenis A., Gourgoulianis K.I., Kostikas K. Clinical, functional and biochemical changes during recovery from COPD exacerbations. Respir. Med. 2009, 103:919-926.
23. Lopez-Campos J.L., Rodriguez-Rodriguez D., Rodriguez-Becerra E., Alfageme Michavila I., Guerra J.F., Hernandez F.J., Casanova A., Fernández de Córdoba Gamero J., Romero-Ortiz A., Arellano-Orden E., Montes-Worboys A. Cyclooxygenase-2 polymorphisms confer susceptibility to sarcoidosis but are not related to prognosis. Respir. Med. 2009, 103:427-433.
24. Malle E., Bollmann A., Steinmetz A., Gemsa D., Leis H.J., Sattler W. Serum amyloid A (SAA) protein enhances formation of cyclooxygenase metabolites of activated human monocytes. FEBS Lett. 1997, 419:215-219.
25. Miller M.R., Hankinson J., Brusasco V., Burgos F., Casaburi R., Coates A., Crapo R., Enright P., van der Grinten C.P., Gustafsson P., Jensen R., Johnson D.C., MacIntyre N., McKay R., Navajas D., Pedersen O.F., Pellegrino R., Viegi G., Wanger J., ATS/ERS Task Force Standardisation of spirometry. Eur. Respir. J. 2005, 26:319-338.
26. Papafili A., Hill M.R., Brull D.J., McAnulty R.J., Marshall R.P., Humphries S.E., Laurent G.J. Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arterioscler. Thromb. Vasc. Biol. 2002, 22:1631-1636.
27. Pietras, T., Szemraj, J., Panek, M., Witusik, A., Banasiak, M., Antczak, A., Górski, P. Functional polymorphism of cyclooxygenase-2 gene (G -) in chronic obstructive pulmonary disease patients. Mol. Biol. Rep., PMID:21655952, in press. pdb:765C.
28. Pinto-Plata V., Toso J., Lee K., Park D., Bilello J., Mullerova H., De Souza M.M., Vessey R., Celli B. Profiling serum biomarkers in patients with COPD: associations with clinical parameters. Thorax 2007, 62:595-601.
29. Pinto-Plata V.M., Mullerova H., Toso J.F., Feudjo-Tepie M., Soriano J.B., Vessey R.S., Celli B.R. C-reactive protein in patients with COPD, control smokers and non-smokers. Thorax 2006, 61:23-28.
30. Profita M., Sala A., Bonanno A., Riccobono L., Ferraro M., La Grutta S., Albano G.D., Montalbano A.M., Gjomarkaj M. Chronic obstructive pulmonary disease and neutrophil infiltration: role of cigarette smoke and cyclooxygenase products. Am. J. Physiol. Lung Cell. Mol. Physiol. 2010, 298:L261-L269.
31. Qiu W., Cho M.H., Riley J.H., Anderson W.H., Singh D., Bakke P., Gulsvik A., Litonjua A.A., Lomas D.A., Crapo J.D., Beaty T.H., Celli B.R., Rennard S., Tal-Singer R., Fox S.M., Silverman E.K., Hersh C.P., the ECLIPSE Investigators Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS ONE 2011, 6:e24395.
32. Ridker P.M. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003, 107:363-369.
33. Rusznak C., Mills P.R., Devalia J.L., Sapsford R.J., Davies R.J., Lozewicz S. Effect of cigarette smoke on the permeability and IL-1beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease. Am. J. Respir. Cell Mol. Biol. 2000, 23:530-536.
34. Smith D.J., Yerkovich S.T., Towers M.A., Carroll M.L., Thomas R., Upham J.W. Reduced soluble receptor for advanced glycation end products in chronic obstructive pulmonary disease. Eur. Respir. J. 2011, 37:516-522.
35. Spurzem J.R., Rennard S.I. Pathogenesis of COPD. Semin. Respir. Crit. Care Med. 2005, 26:142-153.
36. Steel D.M., Whitehead A.S. The major acute-phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein. Immunol. Today 1994, 15:81-88.
37. Wu L., Merrilees M., Young R.P., Black P.N. The cyclooxygenase-2 -765C promoter polymorphism protects against the development of chronic obstructive pulmonary disease. Respir. Med. 2011, 105:506-510.
38. Xaubet A., Roca-Ferrer J., Pujols L., Ramírez J., Mullol J., Marin-Arguedas A., Torrego A., Gimferrer J.M., Picado C. Cyclooxygenase-2 is up-regulated in lung parenchyma of chronic obstructive pulmonary disease and down-regulated in idiopathic pulmonary fibrosis. Sarcoidosis Vasc. Diffuse Lung Dis. 2004, 21:35-42.