Effects and mechanisms of total Panax notoginseng saponins on proliferation of vascular smooth muscle cells with plasma pharmacology method

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 1, 2012, Pages 139-145

  Zhang, Wei ^a   Chen, Gang ^a   Deng, Chang Qing ^a  

^a HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

cyclin dependent kinase 4; cyclinD1; mitogen activated protein kinase; total Panax notoginseng saponin; vascular smooth muscle cell

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ATORVASTATIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLINE; GINSENOSIDE RB 1; GINSENOSIDE RG 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOTOGINSENOSIDE R1; PANAX NOTOGINSENG EXTRACT; PLATELET DERIVED GROWTH FACTOR; PROTEIN C FOS; PROTEIN P21; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; INTRACELLULAR SIGNALING; MALE; MUSCLE CELL; NONHUMAN; PANAX NOTOGINSENG; PROTEIN CONTENT; RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASES; DOWN-REGULATION; DRUGS, CHINESE HERBAL; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, ANIMAL; MUSCLE, SMOOTH, VASCULAR; PANAX NOTOGINSENG; PHYTOTHERAPY; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 83555176174     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2011.01379.x     Document Type: Article

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