A prospective phase II study evaluating the efficacy of oral immune modulating formulae on acute oral mucositis during radiochemotherapy in head and neck neoplasms

e-SPEN

Volumn 6, Issue 4, 2011, Pages

  Assenat, E ^a   Latournerie, M ^a   Thezenas S ^a   Gaillet, S ^b   Janiszewski, C ^a   Flori, N ^a   Dupuy, A M ^b   Azria, D ^a   Crapez, E ^a   Garrel, R ^b   Senesse, P ^a  

^a CENTRE VAL D AURELLE   (France)

^b MONTPELLIER UNIVERSITY HOSPITAL   (France)

Author keywords

Adult; Diet therapy; Food formulated; Head and neck neoplasms; Radiochemotherapy; Toxicities

Indexed keywords

ARGININE; CARBOPLATIN; CISPLATIN; FLUOROURACIL; OMEGA 3 FATTY ACID; RNA;

ADULT; AGED; AGEUSIA; ANOREXIA; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CHEMORADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DIET SUPPLEMENTATION; DYSGEUSIA; DYSPHONIA; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HEMATOLOGIC DISEASE; HUMAN; IMMUNOMODULATION; MALE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NAUSEA AND VOMITING; NUTRITIONAL SUPPORT; ORAL MUCOSITIS; PATIENT COMPLIANCE; RADIATION DOSE; SKIN INFLAMMATION; STOMATITIS; XEROSTOMIA;

EID: 83555173373     PISSN: None     EISSN: 17514991     Source Type: Journal    
DOI: 10.1016/j.eclnm.2011.03.001     Document Type: Article

References (37)

1. Cooper J.S., Pajak T.F., Forastiere A.A., et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004, 350:1937-1944.
2. Bernier J., Domenge C., Ozsahin M., et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004, 350:1945-1952.
3. Trotti A., Bellm L.A., Epstein J.B., et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother Oncol 2003, 66:253-263.
4. Bonner J.A., Harari P.M., Giralt J., et al. Radiotherapy plus cetuximab for squamous cell carcinoma of the head and neck. N Engl J Med 2006, 354:567-578.
5. Tarnawski R., Fowler J., Skladowski K., et al. How fast is repopulation of tumor cells during the treatment gap?. Int J Radiat Oncol Biol Phys 2002, 54:229-236.
6. Herrmann T., Baumann M. Prolongation of latency or overall treatment time by unplanned radiation pauses. The clinical importance of compensation. Strahlenther Onkol 2005, 181:65-76.
7. Rosenthal D.I., Liu L., Lee J.H., et al. Importance of the treatment package time in surgery and postoperative radiation therapy for squamous carcinoma of the head and neck. Head Neck 2002, 24:115-126.
8. Suwinski R., Sowa A., Rutkowski T., et al. Time factor in postoperative radiotherapy: a multivariate locoregional control analysis in 868 p.tients. Int J Radiat Oncol Biol Phys 2003, 56:399-412.
9. Langendijk J.A., de Jong M.A., Leemans C.R., et al. Postoperative radiotherapy in squamous cell carcinoma of the oral cavity: the importance of the overall treatment time. Int J Radiat Oncol Biol Phys 2003, 57:693-700.
10. Pignon J.P., Bourhis J., Domenge C., Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-analysis of chemotherapy on head and neck cancer. Lancet 2000, 355:949-955.
11. Scolapio J.S., Spangler P.R., Romano M.M., et al. Prophylactic placement of gastrostomy feeding tubes before radiotherapy in patients with head and neck cancer: is it worthwhile?. J Clin Gastroenterol 2001, 33:215-217.
12. Piquet M.A., Ozsahin M., Larpin I., et al. Early nutritional intervention in oropharyngeal cancer patients undergoing radiotherapy. Support Care Cancer 2002, 10:502-504.
13. Lee J.H., Machtay M., Unger L.D., et al. Prophylactic gastrostomy tubes in patients undergoing intensive irradiation for cancer of the head and neck. Arch Otolaryngol Head Neck Surg 1998, 124:871-875.
14. Ravasco P., Monteiro-Grillo I., Marques Vidal P., Camilo M.E. Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy. Head Neck 2005, 27:659-668.
15. van Bokhorst-De Van Der Schueren M.A., Quak J.J., von Blomberg-van der Flier B.M., et al. Effect of perioperative nutrition, with and without arginine supplementation, on nutritional status, immune function, postoperative morbidity, and survival in severely malnourished head and neck cancer patients. Am J Clin Nutr 2001, 73:323-332.
16. de Luis D.A., Izaola O., Cuellar L., et al. Randomized clinical trial with an enteral arginine-enhanced formula in early postsurgical head and neck cancer patients. Eur J Clin Nutr 2004, 58:1505-1508.
17. Fearon K.C., Barber M.D., Moses A.G., et al. Double-blind, placebo-controlled, randomized study of eicosapentaenoic acid diester in patients with cancer cachexia. J Clin Oncol 2006, 24:3401-3407.
18. Senkal M., Zumtobel V., Bauer K.H., et al. Outcome and cost-effectiveness of perioperative enteral specialized diet in patients undergoing elective upper gastrointestinal tract surgery: a prospective randomized study. Arch Surg 1999, 134:1309-1316.
19. Braga M., Gianotti L., Nespoli L., et al. Nutritional approach in malnourished surgical patients: a prospective randomized study. Arch Surg 2002, 137:174-180.
20. Gianotti L., Braga M., Nespoli L., et al. A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer. Gastroenterology 2002, 122:1763-1770.
21. Snyderman C.H., Kachman K., Molseed L., et al. Reduced postoperative infections with an immune-enhancing nutritional supplement. Laryngoscope 1999, 109:915-921.
22. Simopoulos A.P. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr 2002, 21:495-505.
23. Wen B., Deutsch E., Opolon P., et al. N-3 p.lyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumor effect of ionising radiation with inhibition of tumour angiogenesis. Br J Cancer 2003, 89:1102-1107.
24. Minami Y., Miyata H., Doki Y., et al. Omega-3 fatty acid-containing diet (Racol) reduces toxicity of chemoradiation therapy for patients with esophageal cancer. Gan To Kagaku Ryoho 2008, 35:437-440.
25. Löser C., Aschl G., Hébuterne X., et al. ESPEN guidelines on artificial enteral nutrition percutaneous endoscopic gastrostomy (PEG). Clin Nutr 2005, 24:848-861.
26. Wang W.S., Lin J.K., Lin T.C., et al. Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients. Oncologist 2007, 12:312-319.
27. Ferreira P.R., Fleck J.F., Diehl A., et al. Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: a double-blind randomized trial. Head Neck 2004, 26:313-321.
28. Isenring E.A., Capra S., Bauer J.D. Nutrition intervention is beneficial in oncology outpatients receiving radiotherapy to the gastrointestinal or head and neck area. Br J Cancer 2004, 91:447-452.
29. Fearon K.C., Von Meyenfeldt M.F., Moses A.G., et al. Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut 2003, 52:1479-1486.
30. Bauer J., Capra S., Battistutta D., et al. Compliance with nutrition prescription improves outcomes in patients with unresectable pancreatic cancer. Clin Nutr 2005, 24:998-1004.
31. Grimble R.F. Effect of antioxidative vitamins on immune function with clinical applications. Int J Vitam Nutr Res 1997, 67:312-320.
32. Yamamoto Y., Gaynor R.B. Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest 2001, 107:135-142.
33. Delerive P., Fruchart J.C., Staels B. Peroxisome proliferator-activated receptors in inflammation control. J Endocrinol 2001, 169:453-459.
34. Dupertuis Y.M., Benais-Pont G., Buchegger F., Pichard C. Effect of an immunonutrient mix on human colorectal adenocarcinoma cell growth and viability. Nutrition 2007, 23:672-680.
35. Siddiqui R.A., Harvey K., Stillwell W. Anticancer properties of oxidation products of docosahexaenoic acid. Chem Phys Lipids 2008, 153:47-56.
36. Colas S., Paon L., Denis F., et al. Enhanced radiosensitivity of rat autochtonous mammary tumors by dietary docosahexaenoic acid. Int J Cancer 2004, 109:449-454.
37. Colas S., Maheo K., Denis F., et al. Sensitization by dietary docosahexaenoic acid of rat mammary carcinoma to anthracyclines: a role for tumor vascularization. Clin Cancer Res 2006, 12:5879-5886.