Achyranthes bidentata root extract prevent OVX-induced osteoporosis in rats

Journal of Ethnopharmacology

Volumn 139, Issue 1, 2012, Pages 12-18

  Zhang, Rong ^a   Hu, Shi Jie ^b   Li, Chen ^a   Zhang, Feng ^a   Gan, Hong Quan ^a   Mei, Qi Bing ^a,c  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

Author keywords

Achyranthes bidentata; Bone turnover; DEXA and CT; Mechanical test; Ovariectomy

Indexed keywords

ACHYRANTHES BIDENTATA EXTRACT; ALKALINE PHOSPHATASE; DEOXYPYRIDINOLINE; ETHINYLESTRADIOL; OSTEOCALCIN;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE MASS; BONE MINERAL; BONE REMODELING; BONE STRENGTH; BONE TURNOVER; CALCIUM URINE LEVEL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOLYSIS; OVARIECTOMY; PLANT ROOT; POSTMENOPAUSE OSTEOPOROSIS; RAT; TRABECULAR BONE; TREATMENT OUTCOME; WEIGHT GAIN;

ACHYRANTHES; ALKALINE PHOSPHATASE; ANIMALS; BONE DENSITY; CALCIUM; CREATININE; DRUGS, CHINESE HERBAL; FEMALE; FEMUR; OSTEOPOROSIS; OVARIECTOMY; PHOSPHORUS; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY;

ACHYRANTHES BIDENTATA; RATTUS;

EID: 83555166212     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.05.034     Document Type: Article

References (42)

1. P. Ammann, R. Rizzoli, J.M. Meyer, and J.P. Bonjour Bone density and shape as determinants of bone strength in IGF-I and/or pamidronate-treated ovariectomized rats Osteoporos. Int. 6 1996 219 227 (Pubitemid 26171275)
2. B.H. Arjmandi, L. Alekel, B.W. Hollis, D. Amin, M. Stacewicz-Sapuntzakis, P. Guo, and S.C. Kukreja Dietary soybean prevents bone loss in an ovariectomized rat model of osteoporosis J. Nutr. 126 1996 161 167 (Pubitemid 26030645)
3. B.H. Arjmandi, R. Birnbaum, N.V. Goyal, M.J. Getlinger, S. Juma, L. Alekel, C.M. Hasler, M.L. Drum, B.W. Hollis, and S.C. Kukreja Bone-sparing effect of soy protein in ovarian hormonedeficient rats is related to its isoflavone content Am. J. Clin. Nutr. 68 6 Suppl 1998 1364S 1368S (Pubitemid 28550913)
4. B.H. Arjmandi, M.J. Getlinger, N.V. Goyal, L. Alekel, C.M. Hasler, S. Juma, M.L. Drum, B.W. Hollis, and S.C. Kukreja Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian deficiency in rats Am. J. Clin. Nutr. 68 6 Suppl 1998 1858S 1863S
5. B. Borah, T.E. Dufresne, P.A. Chmielewski, G.J. Gross, M.C. Prenger, and R.J. Phipps Ris edronate preserves trabecular architecture and increases bone strength in vertebra of ovariectomized minipigs as measured by threedimensional microcomputed tomography J. Bone Miner. Res. 17 2002 1139 1147 (Pubitemid 34680488)
6. L. Dalle Carbonare, M.E. Arlot, P.M. Chavassieux, J.P. Roux, N.R. Portero, and P.J. Meunier Comparison of trabecular bone microarchitecture and remodeling in glucocorticoid-induced and postmenopausal osteoporosis J. Bone Miner. Res. 16 2001 97 103 (Pubitemid 32046193)
7. S. Davison, and S.R. Davis Hormone replacement therapy: current controversies Clin. Endocrinol. (Oxf) 58 2003 249 261 (Pubitemid 36308111)
8. C. Deal Potential new drug targets for osteoporosis Nat. Clin. Pract. Theum. 5 2009 20 27
9. L. Devareddy, D.A. Khalil, B.J. Smith, E.A. Lucas, D.T. Soung, D.D. Marlow, and B.H. Arjmandi Soy moderately improves microstructural properties without affecting bone mass in an ovariectomized rat model of osteoporosis Bone 38 2006 686 693
10. A.G. Ederveen, C.P. Spanjers, J.H. Quaijtaal, and H.J. Kloosterboer Effect of 16 months of treatment with tibolone on bone mass, turnover, and biomechanical quality in mature ovariectomized rats J. Bone Miner. Res. 16 2001 1674 1681 (Pubitemid 32786437)
11. S.J. Fairweather-Tait, and B. Teucher Calcium bioavailability in relation to bone health Int. J. Vitam. Nutr. Res. 72 2002 13 18 (Pubitemid 34186301)
12. V.L. Feigin Herbal medicine in stroke: does it have a future? Stroke 38 2007 1734 1736 (Pubitemid 46847228)
13. X.Y. Gao, D.W. Wang, and F.M. Li Determination of ecdysterone in Achyranthes bidentata BL. and its activity promoting proliferation of osteoblast-like cells Yao Xue Xue Bao 35 2000 868 870
14. N. Gaumet, M.J. Seibel, V. Coxam, M.J. Davicco, P. Lebecque, and J.P. Barlet Influence of ovariectomy and estradiol treatment on calcium homeostasis during aging in rats Arch. Physiol. Biochem. 105 1997 435 444 (Pubitemid 28068230)
15. Guide for the Care and Use of Laboratory Animals, 1996. National Academy Press, Washington, DC.
16. S. Hidaka, Y. Okamoto, K. Nakajima, M. Suekawa, and S.Y. Liu Preventive effects of traditional Chinese (Kampo) medicines on experimental osteoporosis induced by ovariectomy in rats Calcified Tissue Int. 61 1997 239 246 (Pubitemid 27360818)
17. D.N. Kalu The ovariectomized rat model of postmenopausal bone loss Bone Miner. 15 1991 175 191
18. S Khosla, and B.L. Riggs Pathophysiology of age-related bone loss and osteoporosis Endocrinol. Metab. Clin. North Am. 34 2005 1015 1030 (Pubitemid 41677410)
19. S. Khosla, J.J. Westendorf, and M.J. Oursler Building bone to reverse osteoporosis and repair fractures J. Clin. Invest. 118 2005 421 428
20. J. Kühnau The flavonoids. A class of semi-essential food components: their role in human nutrition World Rev. Nutr. Diet 24 1976 117 191
21. A. Laib, J.L. Kumer, S. Majumdar, and N.E. Lane The temporal changes of trabecular architecture in ovariectomized rats assessed by MicroCT Osteoporos. Int. 12 2001 936 941 (Pubitemid 34001007)
22. J.X. Li, T. Hareyama, Y. Tezuka, g.Y. Zhan, T. Miyahara, and S. Kadota Five new oleanolic acid glycosides from Achyranthes bidentata with inhibitory activity on osteoclast formation Planta Med. 71 2005 673 679 (Pubitemid 41133079)
23. Z.G. Liu, R. Zhang, C. Li, X. Ma, L. Liu, J.P. Wang, and Q.B. Mei The osteoprotective effect of Radix Dipsaci extract in ovariectomized rats J. Ethnopharmacol. 123 2009 74 81
24. D.L. Meng, and X. Li The research development in the chemical constituents and pharmacological activities of Achyranthes bidentata Bl Chin. J. Med. Chem. 11 2001 120 124
25. Nicolov stefan, Thuan Ngugen, and Zheljazlov Valcho Flavonoids from Achyranthes bidentata BI Acta Hoctic 426 1996
26. T. Notomi, N. Okimoto, Y. Okazaki, T. Nakamura, and M. Suzuki Tower climbing exercise started 3 months after ovariectomy recovers bone strength of the femur and lumbar vertebrae in aged osteopenic rats J. Bone Miner. Res. 18 2003 140 149 (Pubitemid 36008350)
27. S.M. Potter, J.A. Baum, H. Teng, R.J. Stillman, N.F. Shays, and J.W. Erdman Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women Am. J. Clin. Nutr. 68 6 Suppl 1998 1375S 1379S (Pubitemid 28550915)
28. G.M. Prelevic, T. Kocjan, and A. Markou Hormone replacement therapy in postmenopausal women Minerva Endocrinol. 30 2005 27 36
29. L. Qin, G. Zhang, Y.Y. Shi, K.M. Lee, and P.C. Leung Prevention and treatment of osteoporosis with traditional herbal medicine H.W. Deng, Current Topics of Osteoporosis 2005 World Scientific Publisher 513 531
30. L.G. Raisz Pathogenesis of osteoporosis: concepts, conflicts, and prospects, J. Clin. Invest. 115 2005 3318 3325 (Pubitemid 43121814)
31. K.D Setchell Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones Am. J. Clin. Nutr. 68 6 Suppl 1998 1333S 1346S (Pubitemid 28550909)
32. Y.F. Shang Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis Nat. Rev. Cancer 6 2006 360 368
33. J.C. Stevenson Justification for the use of HRT in the long-term prevention of Osteoporosis Maturitas 51 2005 113 126 (Pubitemid 40726109)
34. K. Taku, M.K. Melby, M.S. Kurzer, S. Mizuno, S. Watanabe, and Y. Ishimi Effects of soy isoflavone supplements on bone turnover markers in menopausal women: systematic review and meta-analysis of randomized controlled trials Bone 47 2010 413 423
35. D. Ulrich, B. van Rietbergen, A. Laib, and P. Ruegsegger The ability of three-dimensional structural indices to reflect mechanical aspects of trabecular bone Bone 25 1999 55 60 (Pubitemid 29322061)
36. E.F. Wagner, and G. Karsenty Genetic control of skeletal development Curr. Opin. Genet. 11 2001 527 532 (Pubitemid 32800726)
37. A. Wattel, S. Kamel, C. Prouillet, J.P. Petit, F. Lorget, E. Offord, and M. Brazier Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NF kappa B and AP-1 J. Cell. Biochem. 15 2004 285 295
38. H. Xu, D. Lawson, A. Kras, and D. Ryan The use of preventive strategies for bone loss Am. J. Chin. Med. 33 2005 299 306 (Pubitemid 40668104)
39. G. Zhang, L. Qin, W.Y. Hung, Y.Y. Shi, P.C. Leung, H.Y. Yeung, and K.S. Leung Flavonoids derived from herbal Epimedium Brevicornum Maxim prevent OVX-induced osteoporosis in rats independent of its enhancement in intestinal calcium absorption Bone 38 2006 818 825 (Pubitemid 44498593)
40. R. Zhang, Z.G. Liu, C. Li, S.J. Hu, L. Liu, J.P. Wang, and Q.B. Mei Du-Zhong (Eucommia ulmoides Oliv.) cortex extract prevent OVX-induced osteoporosis in rats Bone 45 2009 553 559
41. Y. Zheng, B. Liu, M. Chen, and T. Chen Supercritical fluid extraction of ecdysterone from the roots of Achyranthes bidentata BL J. Sep. Sci. 31 2008 1393 1398 (Pubitemid 351736502)
42. Zhonghua Renmin Gongheguo wei sheng bu yao dian wei yuan hui Pharmacopoeia of the People's Republic of China 2000 Chemical Industry Press Beijing, China