Losing control cancer's catastrophic transition

Nucleus

Volumn 2, Issue 4, 2011, Pages 1-4

  Rajapakse, Indika ^a   Scalzo, David ^a   Groudine, Mark ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Chromosome shattering; Differentiation; Replication timing

Indexed keywords

ARTICLE; CARCINOGENESIS; CENTROMERE; CHROMOSOME; CHROMOSOME CONDENSATION; CHROMOSOME REARRANGEMENT; CHROMOSOME REPLICATION; CONFORMATIONAL TRANSITION; COPY NUMBER VARIATION; DNA SEQUENCE; GENE MUTATION; GENE REARRANGEMENT; GENE SWITCHING; MITOSIS; NEOPLASM; TELOMERE;

EID: 83455228375     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, Mudie LJ, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011; 144:27-40.
2. Meyerson M, Pellman D. Cancer genomes evolve by pulverizing single chromosomes. Cell 2011; 144:9-10.
3. Camps J, Ried T. F1000com/7848958 2011.
4. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-674.
5. Hartwell L, Hood L, Goldberg M, Reynolds N, Silver L, Veres R. Genetics: from genes to genomes. Columbus, McGraw-Hill 2006.
6. Rao PN, Johnson RT. Mammalian cell fusion: studies on the regulation of DNA synthesis and mitosis. Nature 1970; 225:159-164.
7. Dimitrova DS, Gilbert DM. The spatial position and replication timing of chromosomal domains are both established in early G1 phase. Molecular Cell 1999; 4:983-993.
8. Smith L, Plug A, Thayer M. Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocations. Proc Natl Acad Sci USA 2001; 98:13300-13305.
9. Breger KS, Smith L, Thayer MJ. Engineering translocations with delayed replication: evidence for cis control of chromosome replication timing. Hum Mol Genet 2005; 14:2813-2827.
10. Stoffregen EP, Donley N, Stauffer D, Smith L, Thayer MJ. An autosomal locus that controls chromosome-wide replication timing and mono-allelic expression. Hum Mol Genet 2011.
11. Hastings PJ, Ira G, Lupski JR. A microhomologymediated break-induced replication model for the origin of human copy number variation. PLoS Genet 2009; 5:1000327.
12. Zhang F, Carvalho CMB, Lupski JR. Complex human chromosomal and genomic rearrangements. Trends Genet 2009; 25:298-307.
13. Rajapakse I, Perlman MD, Scalzo D, Kooperberg C, Groudine M, Kosak ST. The emergence of lineagespecific chromosomal topologies from coordinate gene regulation. Proc Natl Acad Sci USA 2009; 106:6679-6684.
14. Rajapakse I, Groudine M. On emerging nuclear order. J Cell Biol 2011; 192:711-721.
15. Rahmani A, Ji M, Mesbahi M, Egerstedt M. Controllability of multi-agent systems from a graphtheoretic perspective. SIAM J. Control Optim 2009; 48:162-186.
16. Strogatz SH. Nonlinear dynamics and chaos-with applications to physics, biology, chemistry and engineering. Macmillan Publishers Limited. 1994; 248-254.
17. Strogatz S. Nonlinear dynamics and chaos: with applications to physics, biology, chemistry and engineering. Perseus Books, Cambridge 1994.