Exposure to novel environment is characterized by an interaction of D1/NMDA receptors underlined by phosphorylation of the NMDA and AMPA receptor subunits and activation of ERK1/2 signaling, leading to epigenetic changes and gene expression in rat hippocampus

Neurochemistry International

Volumn 60, Issue 1, 2012, Pages 55-67

  Sarantis, Konstantinos ^a   Antoniou, Katerina ^b   Matsokis, Nikolaos ^c   Angelatou, Fevronia ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY OF IOANNINA   (Greece)

^c UNIVERSITY OF PATRAS   (Greece)

Author keywords

Dopamine; ERK1 2; Histone modification; Immediate early genes; NMDA; Phosphorylation

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALPHA [AMINO(4 AMINOPHENYLTHIO)METHYLENE] 2 (TRIFLUOROMETHYL)PHENYLACETONITRILE; AMPA RECEPTOR; DIZOCILPINE; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCARINIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN C FOS; SCOPOLAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EPIGENETICS; GENE EXPRESSION; HABITUATION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HISTONE ACETYLATION; HISTONE PHOSPHORYLATION; IMMEDIATE EARLY GENE; MALE; MEMORY CONSOLIDATION; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; ENVIRONMENT; EPIGENESIS, GENETIC; GENE EXPRESSION; GENES, IMMEDIATE-EARLY; GLUTAMIC ACID; HIPPOCAMPUS; MALE; MAP KINASE SIGNALING SYSTEM; MEMORY; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PREFRONTAL CORTEX; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, DOPAMINE D1; RECEPTORS, N-METHYL-D-ASPARTATE;

RATTUS;

EID: 83455219632     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.10.018     Document Type: Article

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