Amphetamine and dopamine-induced immediate early gene expression in striatal neurons depends on postsynaptic NMDA receptors and calcium

Journal of Neuroscience

Volumn 16, Issue 13, 1996, Pages 4231-4239

  Konradi, Christine ^a   Leveque, Jean Christophe ^a   Hyman, Steven E ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

amphetamine; CREB; dopamine; Fos; immediate early genes; NMDA; striatum

Indexed keywords

AMPHETAMINE; CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIZOCILPINE; DOPAMINE; FORSKOLIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; CORPUS STRIATUM; DRUG INHIBITION; FETUS; GENE INDUCTION; IMMEDIATE EARLY GENE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

EID: 0030013514     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-13-04231.1996     Document Type: Article

References (68)

1. Amador M, Dani JA (1991) MK-801 inhibition of nicotinic acetylcholine receptor channels. Synapse 7:207-215.
2. Bading H, Ginty DD, Greenberg ME (1993) Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 260:181-186.
3. Berger SL, Chirgwin JM (1989) Isolation of RNA. Methods Enzymol 180:3-13.
4. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
5. Butcher SP, Fairbrother IS, Kelly JS, Arbuthnott GW (1988) Amphetamine-induced dopamine release in the rat striatum: an in vivo microdialysis study. J Neurochem 50:346-355.
6. Cepeda C, Buchwald NA, Levine MS (1993) Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated. Proc Natl Acad Sci USA 90:9576-9580.
7. 2+ block of NMDA receptor channels as a mechanism of modulation. Nature 356:521-523.
8. Cole RL, Konradi C, Douglass J, Hyman SE (1995) Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron 14:813-823.
9. Danielson PE, Forss-Petter S, Brow MA, Calavetta L, Douglass J, Milner RJ, Sutcliffe JG (1988) p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA 7:261-267.
10. 2+/calmodulin - as well as cAMP-dependent protein kinase. Proc Natl Acad Sci USA 88:5061-5065.
11. De Montis MG, Devoto P, Meloni D, Gambarana C, Giorgi G, Tagliamonte A (1992) NMDA receptor inhibition prevents tolerance to cocaine. Pharmacol Biochem Behav 42:179-182.
12. Douglass J, McKinzie AA, Pollock KM (1994) Identification of multiple DNA elements regulating basal and protein kinase A-induccd transcriptional expression of the rat prodynorphin gene. Mol Endocrinol 8:333-344.
13. Dragunow M, Faull RL (1990) MK801 induces c-fos protein in thalamic and neocortical neurons of rat brain. Neuroscience Lett 113:144-150.
14. Feinberg AP, Vogelstein B (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13.
15. Foster AC, Wong EHF (1987) The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain. Br J Pharmacol 91:403-409.
16. Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME (1993) Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and circadian clock. Science 260:238-241.
17. Gonzalez GA, Montminy MR (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680.
18. Graybiel AM, Moratalla R, Robertson HA (1990) Amphetamine and cocaine induce drug specific activation of the c-fos gene in striosomematrix compartments and limbic subdivisions of the striatum. Proc Natl Acad Sci USA 87:6912-6916.
19. Hattori K, Angel P, LeBeau MM, Karin M (1988) Structure and chromosomal location of the functional intronless human JUN protooncogene. Proc Natl Acad Sci USA 85:9148-9152.
20. Hoeffler JP, Meyer TE, Yun Y, Jameson JL, Habener JF (1988) Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental DNA. Science 242:1430-1433.
21. Hoffman DC (1994) The noncompetitive NMDA antagonist MK-801 fails to block amphetamine-induced place conditioning in rats. Pharmacol Biochem Behav 47:907-912.
22. Hollmann M, Heinemann S (1994) Cloned glutamate receptors. Ann Rev Neurosci 17:31-108.
23. Hope B, Kosofsky B, Hyman SE, Nestler EJ (1992) Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. Proc Natl Acad Sci USA 89:5764-5768.
24. Itzhak Y, Stein I (1992) Sensitization to the toxic effects of cocaine in mice is associated with the regulation of N-methyl-D-aspartate receptors in the cortex. J Pharmacol Exp Ther 262:464-470.
25. 3H]MK-801 with multiple states of the N-methyl-D-aspartate receptor complex of rat brain. Proc Natl Acad Sci USA 86:740-744.
26. Johnson KM, Jeng Y-J (1991) Pharmacological evidence for N-methyl-D-aspartate receptors on nigrostriatal dopaminergic nerve terminals. Can J Physiol Pharmacol 69:1416-1421.
27. Karler R, Calder LD, Chaudhry IA, Turkanis SA (1989) Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801. Life Sci 45:599-606.
28. Kashihara K, Hamamura T, Okumura K, Otsuki S (1990) Effect of MK-801 on endogenous dopamine release in vivo. Brain Res 528:80-82.
29. Kavanaugh MP, Tester BA, Weber E (1989) Interaction of MK-801 with the nicotinic acetylcholine receptor-associated ion channel from electroplax. Eur J Pharmacol 164:397-398.
30. Kebabian JW, Calne DB (1979) Multiple receptors for dopamine. Nature 277:93-96.
31. Klawans HL, Margolin DI, Dava N, Crosset P (1978) Supersensitivity to D-amphetamine and apomorphine-induced stereotyped behavior induced by chronic D-amphetamine administration. J Neurol Sci 25:283-289.
32. Konradi C, Cole RL, Heckers S, Hyman SE (1994) Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J Neurosci 14:5623-5634.
33. Konradi C, Cole RL, Green D, Senatus P, Leveque J-C, Pollack A, Grossbard SJ, Hyman SE (1995) Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures. J Neurochem 65:1007-1015.
34. 3H]MK-801 binding sites in post-mortem human frontal cortex. Eur J Pharmacol 162:483-490.
35. Kosofsky BE, Genova LM, Hyman SE (1995) Substance P phenotype defines specificity of c-fos induction by cocaine in developing rat striatum. J Comp Neurol 351:41-50.
36. Krebs MO, Desce JM, Kernel ML, Gauchy C, Godeheu G, Cheramy A, Glowinski J (1991) Glutamatergic control of dopamine release in the rat striatum: evidence for presynaptic N-methyl-D-aspartate receptors on dopaminergic nerve terminals. J Neurochem 56:81-85.
37. Lerea LS, McNamara JO (1993) Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways. Neuron 10:31-41.
38. Lerea LS, Butler LS, McNamara JO (1992) NMDA and non-NMDA receptor-mediated increase of c-fos mRNA in dentate gyrus neurons involves calcium influx via different routes. J Neurosci 12:2973-2981.
39. MacDermott AB, Mayer ML, Westbrook GL, Smith SJ, Barker JL (1986) NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 321:519-522.
40. McMillan BA (1983) CNS stimulants: two distinct mechanisms of action for amphetamine-like drugs. Trends Pharmacol Sci 4:429-432.
41. 1 dopamine receptor linked to adenylyl cyclase activation. Proc Natl Acad Sci USA 87:6723-6727.
42. Montminy MR, Bilezikjian LM (1987) Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 328:175-178.
43. Moore KE (1977) The actions of amphetamine on neurotransmitters: a brief review. Biol Psychol 12:451-462.
44. Moratalla R, Robertson HA, Graybiel AM (1992) Dynamic regulation of NGFI-A (zif 268, egr1) gene expression in the striatum. J Neurosci 12:2609-2622.
45. Munson PJ, Rodbard D (1980) Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220-239.
46. Nguyen TV, Kobierski L, Comb M, Hyman SE (1990) The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer. J Neurosci 10:2825-2833.
47. Nguyen TV, Kosofsky B, Birnbaum R, Cohen BM, Hyman SE (1992) Differential expression of c-fos and zif 268 in rat striatum after haloperidol, clozapine and amphetamine. Proc Natl Acad Sci USA 89:4270-4274.
48. Ohno M, Yoshida H, Watanabe S (1994) NMDA receptor-mediated expression of Fos protein in the rat striatum following methamphetamine administration: relation to behavioral sensitization. Brain Res 665:135-140.
49. Olney JW, Labruyere J, Price MT (1989) Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244:1360-1362.
50. Robertson LM, Kerppola TK, Vendrell M, Luk D, Smeyne RJ, Bocchiaro C, Morgan JI, Curran T (1995) Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron 14:241-252.
51. Robinson TE, Becker JB (1986) Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res 396:157-198.
52. Runkel L, Shaw PE, Herrera RE, Hipskind RA, Nordheim A (1991) Multiple basal promotor elements determine the level of human c-fos transcription. Mol Cel Biol 11:1270-1280.
53. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning, 2nd Ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
54. Sassone-Corsi P, Sisson JC, Verma IM (1988a) Transcriptional autoregulation of the proto-oncogene fos. Nature 334:314-319.
55. Sassone-Corsi P, Visvader J, Ferland L, Mellon PL, Verma IM (1988b) Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element. Genes Dev 2:1529-1538.
56. Segal DS, Weinberger SB, Cahill T, McCunney SJ (1980) Multiple daily amphetamine administration: behavioral and neurochemical alterations. Science 207:904-906.
57. Sheng M, McFadden G, Greenberg ME (1990) Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4:571-582.
58. Sheng M, Thompson MA, Greenberg ME (1991) CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252:1427-1430.
59. Snyder-Keller AM (1991) Striatal c-fos induction by drugs and stress in neonatally dopamine-depleted rats given nigral transplants: importance of NMDA activation and relevance to sensitization phenomena. Exp Neurol 113:155-165.
60. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev 8:2527-2539.
61. Surmeier DJ, Bargas J, Hemmings Jr HC, Nairn AC, Greengard P (1995) Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron 14:385-397.
62. Torres G, Rivier C (1993) Cocaine-induced expression of striatal c-fos in the rat is inhibited by NMDA receptor antagonists. Brain Res Bull 30:173-176.
63. Wang JQ, Daunais JB, McGinty JF (1994) NMDA receptors mediate amphetamine-induced upregulation of zif/268 and preprodynorphin mRNA expression in rat striatum. Synapse 18:343-353.
64. Wang KT (1991) Presynaptic glutamate receptors modulate dopamine release from striatal synaptosomes. J Neurochem 57:819-822.
65. Wolf ME, Jeziorski M (1993) Coadministralion of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization. Brain Res 613:291-294.
66. Wong EHF, Kemp JA, Priestley T, Knight AR, Woodruff GN, Iversen LL (1986) The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Adad Sci USA 83:7104-7108.
67. 3H]MK-801 labels a site on the N-methyl-D-aspartate receptor channel complex in rat brain membranes. J Neurochem 50:274-281.
68. Young ST, Porrino LJ, Iadarola MJ (1991) Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors. Proc Natl Acad Sci USA 88:1291-1295.