Enhanced phosphorylation of caveolar PKC-α limits peptide internalization in lung endothelial cells

Molecular and Cellular Biochemistry

Volumn 360, Issue 1-2, 2012, Pages 309-320

  Hutchinson, Tarun E ^a   Zhang, Jianliang ^a   Xia, Shen Ling ^a,b   Kuchibhotla, Sudeep ^a   Block, Edward R ^a,b   Patel, Jawaharlal M ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Calcium release; Caveolae; Lung endothelium; Peptide internalization; PKC phosphorylation

Indexed keywords

CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; PEPTIDE; PEPTIDE P1; PHORBOL ESTER; PROTEIN KINASE C ALPHA; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CAVEOLA; CELL DISRUPTION; CELL FUNCTION; CELL GROWTH; CELL STIMULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; INTERNALIZATION; LUNG ENDOTHELIUM; MEDIATOR; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REDUCTION;

ANIMALS; BETA-CYCLODEXTRINS; CALCIUM SIGNALING; CAVEOLAE; CAVEOLIN 1; CELLS, CULTURED; ENDOCYTOSIS; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME ACTIVATORS; FILIPIN; LUNG; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; SWINE; TETRADECANOYLPHORBOL ACETATE;

EID: 83455210523     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1070-4     Document Type: Article

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