Current knowledge of (pro)renin receptor as an accessory protein of vacuolar H+-ATPase

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 12, Issue 4, 2011, Pages 638-640

  Ichihara, Atsuhiro ^a   Kinouchi, Kenichiro ^b  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

(P)RR; RAS; V ATPase

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN II; MITOGEN ACTIVATED PROTEIN KINASE; PRORENIN; PRORENIN RECEPTOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; RENIN; SYNAPTOPHYSIN;

ARTICLE; CELL VACUOLE; CYTOSOL; INTRACELLULAR SIGNALING; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANIMALS; HUMANS; MODELS, BIOLOGICAL; RECEPTORS, CELL SURFACE; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 83455206286     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320311429227     Document Type: Article

References (15)

1. Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest. 2002 ; 109: 1417-1427 (Pubitemid 34596167)
2. Nishi T, Forgac M. The vacuolar (H+)-ATPases-nature's most versatile proton pumps. Nat Rev Mol Cell Biol. 2002 ; 3: 94-103
3. Ludwig J, Kerscher S, Brandt U, Pfeiffer K, Getlawi F, Apps DK, et al. Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. J Biol Chem. 1998 ; 273: 10939-10947 (Pubitemid 28204933)
4. Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N. Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci U S A. 2004 ; 101: 12792-12797 (Pubitemid 39167537)
5. Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, et al. Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science. 2010 ; 327: 459-463
6. Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, Kurauchi-Mito A, et al. The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res. 2010 ; 107: 30-34
7. Oshima Y, Kinouchi K, Ichihara A, Sakoda M, Kurauchi-Mito A, Bokuda K, et al. (Pro)renin Receptor Is Essential for Normal Podocyte Structure and Function. J Am Soc Nephrol. 2011 ;:
8. Riediger F, Quack I, Qadri F, Hartleben B, Park JK, Potthoff SA, et al. Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol. 2011 ;:
9. Kinouchi K, Ichihara A, Itoh H. Functional characterization of (pro)renin receptor in association with V-ATPase. Front Biosci. 2011 ; 17: 3216-3223
10. Schefe JH, Neumann C, Goebel M, Danser J, Kirsch S, Gust R, et al. Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren. J Hypertens. 2008 ; 26: 1787-1794
11. Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G. Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension. 2009 ; 53: 1077-1082
12. Yoshikawa A, Aizaki Y, Kusano KI, Kishi F, Susumu T, Iida S, et al. The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space. Hypertens Res. 2011 ; 34: 599-605
13. Louagie E, Taylor NA, Flamez D, Roebroek AJ, Bright NA, Meulemans S, et al. Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate. Proc Natl Acad Sci U S A. 2008 ; 105: 12319-12324
14. Nguyen G, Contrepas A. Physiology and pharmacology of the (pro)renin receptor. Curr Opin Pharmacol. 2008 ; 8: 127-132
15. Gonzalez AA, Lara LS, Luffman C, Seth DM, Prieto MC. Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats. Hypertension. 2011 ; 57: 859-864