Maternal/newborn genotype contribution of the renin-angiotensin system (Met235Thr, Thr174Met, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A- AT2R2, 83A/G-REN) to the risk of pre-eclampsia: A Romanian study

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 12, Issue 4, 2011, Pages 539-548

  Procopciuc, Lucia Maria ^a   Caracostea, Gabriela ^a   Zaharie, Gabriela ^a   Puscas, Mariana ^a   Iordache, Georgiana ^a   Popa, Monica ^a   Colcear, Doina ^a   Olteanu, Ileana ^a   Stamatian, Florin ^a  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

Maternal RAS polymorphisms; newborn RAS polymorphisms; PCR RFLP; pre eclampsia; Romania

Indexed keywords

ALANINE; ANGIOTENSIN; ASPARTIC ACID; CYSTEINE; GLYCINE; ISOLEUCINE; METHIONINE; RENIN; THREONINE;

ADULT; AMINO ACID SEQUENCE; ARTICLE; BLOOD PRESSURE REGULATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GESTATIONAL AGE; HUMAN; HUMAN CELL; LOW BIRTH WEIGHT; MOTHER; NEWBORN; NEWBORN PERIOD; PREECLAMPSIA; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; ROMANIA;

ADULT; ELECTROPHORESIS, AGAR GEL; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT, NEWBORN; MOTHERS; MUTATION; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; PRE-ECLAMPSIA; PREGNANCY; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM; RISK FACTORS; ROMANIA;

EID: 83455206282     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320311399603     Document Type: Article

References (32)

1. Redman CW, Sargent IL. Latest advances in understanding pre-eclampsia. Science. 2005 ; 308: 1592-1594
2. Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005 ; 365: 785-799 (Pubitemid 40311367)
3. Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. Br Med J. 2005 ; 330: 565
4. Carey RM, Siragy HM. Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation. Endocr Rev. 2003 ; 24 (3). 261-271 (Pubitemid 36733542)
5. Takimoto E, Ishida J, Sugiyama F, Horiguchi H, Murakami K, Fukamizu A. Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen. Science. 1996 ; 274: 995-998 (Pubitemid 26398424)
6. Levesque S, Moutquin JM, Lindsay C, Roy MC, Rousseau F. Implication of an AGT haplotype in a multigene association study with pregnancy hypertension. Hypertension. 2004 ; 43: 71-78 (Pubitemid 38031913)
7. Morgan T, Craven C, Lalouel JM, Ward K. Angiotensinogen Thr235 variant is associated with abnormal physiologic change of the uterine spiral arteries in firsttrimester decidua. Am J Obstet Gynecol. 1999 ; 180: 95-102 (Pubitemid 29088396)
8. Rigat B, Hubert C, Henc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 1990 ; 86: 1343-1346 (Pubitemid 20370444)
9. Rupert JL, Kidd KK, Norman LE, Monsalve MV, Hochachka PW, Devine DV. Genetic polymorphisms in the renin-angiotensin system in high altitude and low altitude native American populations. Ann Hum Genet. 2003 ; 67: 17-25 (Pubitemid 38312846)
10. Cnattingius S, Reilly M, Pawitan Y, Lichtenstein P. Maternal and fetal genetic factors account for most of familial aggregation of pre-eclampsia: a population-based Swedish cohort study. Am J Med Genet. 2004 ; 130: 365-371 (Pubitemid 39441611)
11. Diagnosis and management of pre-eclampsia and eclampsia. Obstet Gynecol. 2002 ; 99: 159
12. Russ AP, Maerz W, Ruzicka V, Stein U, Gross W. Rapid detection of the hypertension-associated Met2353Thr allele of the human angiotensinogen gene. Hum Mol Genet. 1993 ; 2: 609-610 (Pubitemid 23140035)
13. Caufield M, Lavender P, Farral M. Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med. 1999 1629 ; 330 :
14. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res. 1992 1433 ; 20 :
15. Katsuya T, Koike G, Yee TW, Sharpe N, Jackson R, Norton R, et al. Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. Lancet. 1995 ; 345: 1600-1603
16. Ramachandran V, Ismail P, Stanslas J, Shamsudin N. Analysis of renin-angiotensin aldosterone system gene polymorphisms in Malaysian essential hypertensive and type 2 diabetic subjects. Cardiovasc Diabetol. 2009 ; 8: 11-23
17. Fatini C, Gensini F, Battaglini B, Prisco D, Cellai AP, Fedi S, et al. Angiotensin converting enzyme DD genotype, angiotensin type 1 receptor CC genotype, and hyperhomocysteinemia increase first-trimester fetal loss susceptibility. Blood Coagul Fibrinolysis. 2000 ; 11: 1-6
18. Kaur R, Jain V, Khuller M, Gupta I, Sherawat BS. Association of angiotensin-converting enzyme gene polymorphism with pregnancy-induced hypertension. Acta Obstet Gynecol Scand. 2005 ; 84: 929-933 (Pubitemid 41400291)
19. Kobashi G. Genetic and environmental factors associated with the development of hypertension in pregnancy. J Epidemiol. 2006 ; 16: 1-8
20. Zafarmand MH, Franx A, Sabour S, Van Der Schouw IT, Grobbee De, Leeuw PW, Bots ML. The M235T variant of the angiotensinogen gene is related to development of self-reported hypertension during pregnancy: The Prospect-EPIC Cohort Study. Hypertens Res. 2008 ; 31: 1299-1305
21. Medica I, Kastrin A, Peterlin B. Genetic polymorphisms in vasoactive genes and pre-eclampsia: a meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2006 ; 131 (2). 115-126
22. Bashford MT, Hefler LA, Vertrees TW, Roa BB, Gregg AR. Angiotensinogen and endothelial nitric oxide synthase gene polymorphisms among Hispanic patients with pre-eclampsia. Am J Obstet Gynecol. 2001 ; 184: 1345-1350
23. Galao AO, de Souza LH, da Costa BE, Scheibe RM, Poli de, Figueiredo CE. Angiotensin-converting enzyme gene polymorphism in pre-eclampsia and normal pregnancy. Am J Obstet Gynecol. 2004 ; 191: 821-824 (Pubitemid 39298117)
24. Levesque S, et al. Implication of an AGT haplotype in a multigene association study with pregnancy hypertension. Hypertension. 2004 ; 43: 71-78 (Pubitemid 38031913)
25. Seremak-Mrozikiewicz A, Dubiel M, Drews K, Breborowicz G, Mrozikiewicz P. 1166C mutation of angiotensin II type 1 receptor gene is correlated with umbilical blood flow velocimetry in women with pre-eclampsia. J Matern Fetal Neonat Med. 2005 ; 17: 117-121 (Pubitemid 40769351)
26. Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene study. Am J Hum Genet. 2005 ; 77: 127-131
27. Akbar SA, Khawaja NP, Brown PR, Tayyeb R, Bamfo J, Nicolaides KH. Angiotensin II type 1 and 2 receptors gene polymorphisms in pre-eclampsia and normal pregnancy in three different populations. Acta Obstet Gynecol Scand. 2009 ; 88: 606-611
28. Maruyama A, Nakayama T, Furuya K, Mizutani Y, Yamamoto T. Association study between the human Renin gene and pre-eclampsia. Hypertens Pregnancy. 2005 ; 24: 39-48 (Pubitemid 40411275)
29. Laivuori H. Genetic aspects of pre-eclampsia. Front Biosci. 2007 ; 12: 2372-2382
30. Arngrimsson R, Bjornsson S, Geirsson RT, Bjornsson H, Walker JJ, Snaedal G. Genetic and familial predisposition to eclampsia and pre-eclampsia in a defined population. Br J Obstet Gynaeco. 1990 ; 97: 762-769 (Pubitemid 20283312)
31. Wilson ML, Goodwin TM, Pan VL, Ingles SA. Molecular epidemiology of pre-eclampsia. Obstet Gynecol Surv. 2003 ; 58: 39-66
32. Morgan L, Crawshaw S, Baker PN, Brookfield JF, Broughton PF, Kalsheker N. Distortion of maternal-fetal angiotensin II type 1 receptor allele transmission in pre-eclampsia. J Med Genet. 1998 ; 35: 632-636 (Pubitemid 28371972)