Two microRNAs, miR-330 and miR-125b-5p, mark the juxtaglomerular cell and balance its smooth muscle phenotype

American Journal of Physiology - Renal Physiology

Volumn 302, Issue 1, 2012, Pages 29-37

  Medrano, Silvia ^a   Monteagudo, Maria C ^a   Sequeira Lopez, Maria Luisa S ^a   Pentz, Ellen S ^a   Ariel Gomez, R ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Homeostasis; JG cells; Kidney microarrays

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; MICRORNA; MICRORNA 125B 5P; MICRORNA 330; MYOSIN HEAVY CHAIN; RENIN; SMOOTHELIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL HYBRIDIZATION; CELL LINEAGE; CONTROLLED STUDY; EPITHELIOID CELL; FEMALE; IN VITRO STUDY; JUXTAGLOMERULAR CELL; KIDNEY CORTEX; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 83455198258     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00460.2011     Document Type: Article

References (25)

1. Bar H, Wende P, Watson L, Denger S, van Eys G, Kreuzer J, Jahn L. Smoothelin is an indicator of reversible phenotype modulation of smooth muscle cells in balloon-injured rat carotid arteries. Basic Res Cardiol 97: 9-16, 2002.
2. Castellanos Rivera RM, Monteagudo MC, Pentz ES, Glenn ST, Gross KW, Carretero O, Sequeira-Lopez MLS, Gomez RA. The transcriptional regulator RBP-J regulates the number and plasticity of renin cells. Physiol Genomics 43: 1021-1028, 2011.
3. Donoso VS, Bailie MD. Effect of colchicine on drug-induced changes in plasma renin concentration in rats. Hypertension 4: 676-680, 1982.
4. Dweep H, Sticht C, Pandey P, Gretz N. miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform 44: 839-847, 2011.
5. Gomez RA, Chevalier RL, Everett AD, Elwood JP, Peach MJ, Lynch KR, Carey RM. Recruitment of renin gene-expressing cells in adult rat kidneys. Am J Physiol Renal Fluid Electrolyte Physiol 259: F660-F665, 1990.
6. Gomez RA, Chevalier RL, Sturgill BC, Johns DW, Peach MJ, Carey RM. Maturation of the intrarenal renin distribution in Wistar-Kyoto rats. J Hypertens 4: s31-s33, 1986.
7. Gomez RA, Lynch KR, Sturgill BC, Elwood JP, Chevalier RL, Carey RM, Peach MJ. Distribution of renin mRNA and its protein in the developing kidney. Am J Physiol Renal Fluid Electrolyte Physiol 257: F850-F858, 1989.
8. Gomez RA, Pentz ES, Jin X, Cordaillat M, Sequeira-Lopez ML. CBP and p300 are essential for renin cell identity and morphological integrity of the kidney. Am J Physiol Heart Circ Physiol 296: H1255-H1262, 2009.
9. Grundmann S, Hans FP, Kinniry S, Heinke J, Helbing T, Bluhm F, Sluijter JP, Hoefer I, Pasterkamp G, Bode C, Moser M. MicroRNA-100 regulates neovascularization by suppression of mammalian target of rapamycin in endothelial and vascular smooth muscle cells. Circulation 123: 999-1009, 2011.
10. Hamill DR, Howell B, Cassimeris L, Suprenant KA. Purification of a WD repeat protein, EMAP, that promotes microtubule dynamics through an inhibition of rescue. J Biol Chem 273: 9285-9291, 1998.
11. Le MT, Xie H, Zhou B, Chia PH, Rizk P, Um M, Udolph G, Yang H, Lim B, Lodish HF. MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Mol Cell Biol 29: 5290-5305, 2009.
12. Lee CT, Risom T, Strauss WM. Evolutionary conservation of microRNA regulatory circuits: an examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogeny. DNA Cell Biol 26: 209-218, 2007.
13. Lee KH, Chen YL, Yeh SD, Hsiao M, Lin JT, Goan YG, Lu PJ. MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation. Oncogene 28: 3360-3370, 2009.
14. Monteys AM, Spengler RM, Wan J, Tecedor L, Lennox KA, Xing Y, Davidson BL. Structure and activity of putative intronic miRNA promoters. RNA 16: 495-505, 2010.
15. Ooi AG, Sahoo D, Adorno M, Wang Y, Weissman IL, Park CY. MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc Natl Acad Sci USA 107: 21505-21510, 2010.
16. Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801, 2004.
17. Pentz ES, Sequeira Lopez ML, Cordaillat M, Gomez RA. Identity of the renin cell is mediated by cAMP and chromatin remodeling: an in vitro model for studying cell recruitment and plasticity. Am J Physiol Heart Circ Physiol 294: H699-H707, 2008.
18. Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci USA 105: 1608-1613, 2008.
19. Sequeira Lopez ML, Pentz ES, Nomasa T, Smithies O, Gomez RA. Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Dev Cell 6: 719-728, 2004.
20. Sequeira-Lopez ML, Pentz ES, Robert B, Abrahamson DR, Gomez RA. Embryonic origin and lineage of juxtaglomerular cells. Am J Physiol Renal Physiol 281: F345-F356, 2001.
21. Sequeira-Lopez ML, Weatherford ET, Borges GR, Monteagudo MC, Pentz ES, Harfe BD, Carretero O, Sigmund CD, Gomez RA. The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol 21: 460-467, 2010.
22. Song L, Tuan RS. MicroRNAs and cell differentiation in mammalian development. Birth Defects Res C Embryo Today 78: 140-149, 2006.
23. Suprenant KA, Dean K, McKee J, Hake S. EMAP, an echinoderm microtubule-associated protein found in microtubule-ribosome complexes. J Cell Sci 104: 445-450, 1993.
24. Taugner R, Hackenthal E. The Juxtaglomerular Apparatus: Structure and Function. Heidelberg: Springer-Verlag, 1989.
25. van der Loop FT, Gabbiani G, Kohnen G, Ramaekers FC, van Eys GJ. Differentiation of smooth muscle cells in human blood vessels as defined by smoothelin, a novel marker for the contractile phenotype. Arterioscler Thromb Vasc Biol 17: 665-671, 1997.