Long-term antioxidant supplementation has no effect on health-related quality of life: The randomized, double-blind, placebo-controlled, primary prevention SU.VI.MAX trial

International Journal of Epidemiology

Volumn 40, Issue 6, 2011, Pages 1605-1616

  Briançon, Serge ^a,b   Boini, Stéphanie ^b   Bertrais, Sandrine ^c   Guillemin, Francis ^a,b   Galan, Pilar ^c,d   Hercberg, Serge ^c,d  

^a UNIVERSITÉ DE LORRAINE   (France)

^b UNIVERSITY HOSPITAL OF NANCY   (France)

^c INSERM   (France)

^d AVICENNE HOSPITAL   (France)

Author keywords

Antioxidants; Health related quality of life; Minerals; Prevention trial; Vitamins

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; MINERAL; SELENIUM; ZINC;

ADULT; ANTIOXIDANT; FOOD SUPPLEMENTATION; LONG-TERM CHANGE; MINERAL; PARTICIPATORY APPROACH; QUALITY OF LIFE; QUESTIONNAIRE SURVEY; SAMPLING; VITAMIN;

ADULT; ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HEALTH STATUS; HUMAN; LONG TERM CARE; MALE; MENTAL HEALTH; PRIMARY PREVENTION; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SHORT FORM 36; TREATMENT DURATION; VITAMIN SUPPLEMENTATION;

ADULT; AGE FACTORS; ANTIOXIDANTS; ASCORBIC ACID; BETA CAROTENE; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FRANCE; HEALTH BEHAVIOR; HUMANS; MALE; MENTAL HEALTH; MIDDLE AGED; MINERALS; PLACEBO EFFECT; PRIMARY PREVENTION; QUALITY OF LIFE; SELENIUM; SEX FACTORS; SOCIOECONOMIC FACTORS; VITAMIN E; ZINC;

EID: 83455162572     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyr161     Document Type: Article

References (44)

1. Blot WJ, Li JY, Taylor PR Et Al. Nutrition Intervention Trials In Linxian, China: Supplementation With Specific Vitamin/Mineral Combinations, Cancer Incidence, and Disease-Specific Mortality In The General Population. J Natl Cancer Inst 1993;85:1483-92.
2. The Alpha-Tocopherol Beta Carotene Cancer Prevention Study Group. The Effect Of Vitamin E and Beta Carotene On The Incidence Of Lung Cancer and Other Cancers In Male Smokers. N Engl J Med 1994;330:1029-35.
3. Omenn GS, Goodman GE, Thornquist MD Et Al. Effects Of A Combination Of Beta Carotene and Vitamin A On Lung Cancer and Cardiovascular Disease. N Engl J Med 1996;334: 1150-55.
4. Hennekens CH, Buring JE, Manson JE Et Al. Lack Of Effect Of Long-Term Supplementation With Beta Carotene On The Incidence Of Malignant Neoplasms and Cardiovascular Disease. N Engl J Med 1996;334:1145-49.
5. Lee IM, Cook NR, Manson JE, Buring JE, Hennekens CH. Beta-Carotene Supplementation and Incidence Of Cancer and Cardiovascular Disease: The Women's Health Study. J Natl Cancer Inst 1999;91:2102-26.
6. Miller ER III, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality. Ann Intern Med 2004;142:37-45.
7. Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality In Randomized Trials Of Antioxidant Supplements For Primary and Secondary Prevention: Systematic Review and Meta-Analysis. JAMA 2007;297: 842-57.
8. Franck E, Bendich A, Denniston M. Use Of Vitaminmineral Supplements By Female Physicians In The United States. Am J Clin Nutr 2000;72:969-75.
9. Balluz L, Kieszak S, Philen R, Mulinare J. Vitamin and Mineral Supplement Use In The United States (NHANES III). Arch Intern Med 2000;9:258-62.
10. Soni MG, Thurmond TS, Miller ER III, Spriggs T, Bendich A, Omaye ST. Safety Of Vitamins and Minerals: Controversies and Perspective. Toxicol Sci 2010;118: 348-55.
11. Archer SL, Stamler J, Moag-Stahlberg A Et Al. Association Of Dietary Supplement Use With Specific Micronutrient Intakes Among Middle-Aged American Men and Women: The INTERMAP Study. J Am Diet Assoc 2005; 105:1106-14.
12. Beitz R, Mensink GBM, Fischer B, Thamm M. Vitaminsdietary Intake and Intake From Dietary Supplements In Germany. Eur J Clin Nutr 2002;56:539-45.
13. Dorant E, Van Der Brandt PA, Hamstra AM Et Al. The Use Of Vitamins, Minerals and Other Dietary Supplements In The Netherlands. Int J Vit Nutr Res 1993;63: 4-10.
14. Mullie P, Clarys P, Hulens M, Vansant G. Socioeconomic, Health, and Dietary Determinants Of Multivitamin Supplements Use In Belgium. Int J Public Health 2011;56:289-94.
15. Li K, Kaaks R, Linseisen J, Rohrmann S. Consistency Of Vitamin and/Or Mineral Supplement Use and Demographic, Lifestyle and Health-Status Predictors: Findings From The European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg Cohort. Br J Nutr 2010;104: 1058-64.
16. Mchugh S, Moon H. Consumer Consumption Of Vitamin and Mineral Food Supplements. London: GFK NOP, 3-28-2008. Report Available at http://www.food.gov.uk (Http://Www.Food.Gov.Uk/Multimedia/Pdfs/Viminsupconsumer.Pdf) (May 2010, Date Last Accessed).
17. Costello RB, Coates P. In The Midst Of Confusion Lies Opportunity: Fostering Quality Science In Dietary Supplement Research. J Am Coll Nutr 2003;20:21-25.
18. Hercberg S, Galan P, Preziosi P Et Al. The SU.VI.MAX Study. A Randomized Placebo-Controlled Trial Of The Health Effects Of Antioxidant Vitamins and Minerals. Arch Intern Med 2004;164:2335-42.
19. Hercberg S, Preziosi P, Briancon S Et Al. A Primary Prevention Trial Using Nutritional Doses Of Antioxidant Vitamins and Minerals In Cardiovascular Diseases and Cancers In A General Population: The SU.VI.MAX Study-Design, Methods, and Participant Characteristics. Control Clin Trials 1998;19:336-51.
20. Hercberg S, Galan P, Preziosi P Et Al. Background and Rationale Behind The SU.VI.MAX Study, A Prevention Trial Using Nutritional Doses Of A Combination Of Antioxidant Vitamins and Minerals To Reduce Cardiovascular Diseases and Cancers. Int J Vit Nutr Res 1998;68: 3-20.
21. Ware JE, Gandek B. Overview Of The SF-36 Health Survey and The International Quality Of Life Assessment (IQOLA) Project. J Clin Epidemiol 1998;51:903-12.
22. Goldberg D, Williams P. A User's Guide To The General Health Questionnaire. Windsor: NFER-Nelson, 1988.
23. LeplèGe A, Ecosse E, Verdier A, Perneger TV. The French SF-36 Health Survey: Translation, Cultural Adaptation and Preliminary Psychometric Evaluation. J Clin Epidemiol 1998;51: 1013-23.
24. Pariente P, Guelfi JD. Inventaires D'auto-ÉValuation De La Psychopathologie Chez L'adulte. 1re Partie: Inventaires Multidirectionnels. Psychiatr Psychobiol 1990;5:49-63.
25. Paul-Dauphin A, Guillemin F, Virion JM, Briançon S. Bias and Precision In Visual Analogue Scales: A Randomised Controlled Trial. Am J Epidemiol 1999;150: 1117-27.
26. Boini S, Briancon S, Guillemin F, Galan P, Hercberg S. Impact Of Cancer Occurrence On Health-Related Quality Of Life: A Longitudinal Pre-Post Assessment. Health Qual Life Outcomes 2004;2:4.
27. Keith ME, Jeejeebhoy KN, Langer A Et Al. A Controlled Clinical Trial Of Vitamin E Supplementation In Patients With Congestive Heart Failure. Am J Clin Nutr 2001;73: 219-24.
28. Brown MA, Goldstein-Shirley J, Robinson J, Casey S. The Effects Of A Multi-Modal Intervention Trial Of Light, Exercise, and Vitamins On Women's Mood. Women Health 2001; 34:93-112.
29. Woo J, Ho SC, Mak YT, Law LK, Cheung A. Nutritional Status Of Elderly Patients During Recovery From Chest Infection and The Role Of Nutritional Supplementation Assessed By A Prospective Randomized Single-Blind Trial. Age Ageing 1994;23:40-48.
30. Krondl M, Coleman PH, Bradley CL, Lau D, Ryan N. Subjectively Healthy Elderly Consuming A Liquid Nutrition Supplement Maintained Body Mass Index and Improved Some Nutritional Parameters and Perceived Well-Being. J Am Diet Assoc 1999;99:1542-48.
31. Barr SI, MC Carron DA, Heany RP Et Al. Effects Of Increased Consumption Of Fluid Milk and Nutrient Intake, Body Weight and Cardiovascular Risk Factors In Healthy Older Adults. J Am Diet Assoc 2000;100: 810-17.
32. Barringer TA, Kirk JK, Santaniello AC, Foley KL, Michielutte R. Effect Of A Multivitamin and Mineral Supplement On Infection and Quality Of Life. A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Intern Med 2003;138:365-71.
33. Moinpour CM, Lovato LC, Thompson IM Jr Et Al. Profile Of Men Randomized To The Prostate Cancer Prevention Trial: Baseline Health-Related Quality Of Life, Urinary and Sexual Functioning, and Health Behaviors. J Clin Oncol 2000;18: 1942-53.
34. Thompson IM, Goodman PJ, Tangen CM Et Al. The Influence Of Finasteride On The Development Of Prostate Cancer. N Engl J Med 2003;349:215-24.
35. Moinpour CM, Darke AK, Donaldson GW Et Al. Longitudinal Analysis Of Sexual Function Reported By Men In The Prostate Cancer Prevention Trial. J Natl Cancer Inst 2007;99:1025-35.
36. Svatek RS, Lee JJ, Roehrborn CG, Lippman SM, Lotan Y. Cost-Effectiveness Of Prostate Cancer Chemoprevention: A Quality Of Life-Years Analysis. Cancer 2008;112: 1058-65.
37. Lippman SM, Goodman PJ, Klein EA Et Al. Designing The Selenium and Vitamin E Cancer Prevention Trial (SELECT). J Natl Cancer Inst 2005;97:94-102.
38. Lippman SM, Klein EA, Goodman PJ Et Al. Effect Of Selenium and Vitamin E On Risk Of Prostate Cancer and Other Cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009;301:39-51.
39. Tatsioni A, Bonitsis NG, Ioannidis JP. Persistence Of Contradicted Claims In The Literature. JAMA 2007;298: 2517-26.
40. Bouchet C, Guillemin F, Paul-Dauphin A, BriançOn S. Selection Of Quality Of Life Measures For A Prevention Trial: A Psychometric Analysis. Control Clin Trials 2000;21: 30-43.
41. Mccabe CJ, Thomas KJ, Brazier JE, Coleman P. Measuring The Mental Health Status Of A Population: A Comparison Of The GHQ-12 and The SF-36 (MHI-5). Br J Psychiatry 1996;169:517-21.
42. Wiklund I, DimenäS E, Wahl M. Factors Of Importance When Evaluating Quality Of Life In Clinical Trials. Control Clin Trials 1990;11:169-79.
43. Brooks MM, Jenkins LS, Schron EB Et Al. Quality Of Life At Baseline. Is Assessment After Randomization Valid? Med Care 1998;36:1515-19.
44. Sanders C, Egger M, Donovan J, Tallon D, Frankel S. Reporting On Quality Of Life In Randomised Controlled Trials: Bibliographic Study. BMJ 1998;317:1191-94.