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Volumn 27, Issue 5, 2004, Pages 361-367

Pharmacokinetics of orally administered pirfenidone in male and female beagles

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBROTIC AGENT; PIRFENIDONE;

EID: 8344247705     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2004.00612.x     Document Type: Article
Times cited : (22)

References (18)
  • 1
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    • (1984) Drug Metabolism Review , vol.15 , pp. 1071-1121
    • Boxenbaum, H.1
  • 2
    • 0033016370 scopus 로고    scopus 로고
    • Development of a general method of limited sampling for the determination of AUC for a drug that displays two-compartment pharmacokinetics
    • Duffull, S.B., Begg, E.J. & Deely, J.J. (1999) Development of a general method of limited sampling for the determination of AUC for a drug that displays two-compartment pharmacokinetics. European Journal of Clinical Pharmacology, 55, 213-219.
    • (1999) European Journal of Clinical Pharmacology , vol.55 , pp. 213-219
    • Duffull, S.B.1    Begg, E.J.2    Deely, J.J.3
  • 3
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    • 0031914475 scopus 로고    scopus 로고
    • Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin hamster model
    • Iyer, S.N., Margolin, S.B., Hyde, D.M. & Giri, S.N. (1998) Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin hamster model. Experimental Lung Research, 24, 119-132.
    • (1998) Experimental Lung Research , vol.24 , pp. 119-132
    • Iyer, S.N.1    Margolin, S.B.2    Hyde, D.M.3    Giri, S.N.4
  • 6
    • 0030246901 scopus 로고    scopus 로고
    • Prediction of furan pharmacokinetics from hepatocyte studies: Comparison of bioactivation and hepatic dosimetry in rats, mice, and humans
    • Kedderis, G. L. & Held, S. D. (1996) Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans. Toxicology and Applied Pharmacology, 140, 124-130.
    • (1996) Toxicology and Applied Pharmacology , vol.140 , pp. 124-130
    • Kedderis, G.L.1    Held, S.D.2
  • 7
    • 0031557123 scopus 로고    scopus 로고
    • Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice
    • Kehrer, J.P. & Margolin, S.B. (1997) Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice. Toxicology Letters, 90, 125-132.
    • (1997) Toxicology Letters , vol.90 , pp. 125-132
    • Kehrer, J.P.1    Margolin, S.B.2
  • 12
    • 0034946204 scopus 로고    scopus 로고
    • Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats
    • Miric, G., Dallemagne, C., Endre, Z., Margolin, S., Taylor, S.M. & Brown. L. (2001) Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats. British Journal of Pharmacology, 133, 687-694.
    • (2001) British Journal of Pharmacology , vol.133 , pp. 687-694
    • Miric, G.1    Dallemagne, C.2    Endre, Z.3    Margolin, S.4    Taylor, S.M.5    Brown, L.6
  • 13
    • 0032926937 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: Results of a prospective, open-label Phase II study
    • Raghu, G., Johnson, W.C., Lockhart, D. & Mageto, Y. (1999) Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label Phase II study. American Journal of Respiratory and Critical Care Medicine, 159, 1061-1069.
    • (1999) American Journal of Respiratory and Critical Care Medicine , vol.159 , pp. 1061-1069
    • Raghu, G.1    Johnson, W.C.2    Lockhart, D.3    Mageto, Y.4
  • 17
    • 0034747862 scopus 로고    scopus 로고
    • Pirfenidone for chronic progressive multiple sclerosis
    • Walker, J.E. and Margolin, S.B. (2001) Pirfenidone for chronic progressive multiple sclerosis. Multiple Sclerosis, 7, 305-312.
    • (2001) Multiple Sclerosis , vol.7 , pp. 305-312
    • Walker, J.E.1    Margolin, S.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.